Clinical trials: sponsored by Region Skane
Self-Injurious Behavior, Suicidal Ideation
Brief Admission Skane: Replacing General Admission for Individuals With Self-harm and Acute Risk of Suicide
The purpose of the study is to test a standardized version of brief admission (BA) through randomized controlled trial (RCT). The main objective is to evaluate if BA can serve as a crisis management model for individuals with…
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide, Attempted, Borderline Personality Disorder
- Trial name
- BAS (NCT02985047)
- Testing
- Brief Admission
- Where
- Sweden
- Volunteers
- 125 people
- Sponsor
- Region Skane
Septic Shock
Survey of Non-resuscitation Fluids in Septic Shock
The objective of this study is to survey the type and the amount of non-resuscitation fluids that patients with septic shock receives during their first 5 days of ICU admission.
- Trial name
- SURF (NCT03438097)
- Where
- 9 sites in Canada, Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Motivation for Physical Activity
A Multi-professional Team Intervention on Physical Activity Referrals in Primary Care Patients With Cardiovascular Risk Factors-the Dalby Lifestyle Intervention Cohort (DALICO) Study
Background The present study protocol describes the trial design of a primary care intervention cohort study, which examines whether an extended, multi-professional physical activity referral (PAR) intervention is more effective…
- Trial name
- DALICO (NCT01187576)
- Testing
- Multi-professional team intervention with PAR, lifestyle brochure, Ordinary recommendations on health behaviours, lifestyle brochure
- Where
- Sweden
- Sponsor
- Region Skane
Low Water Intake, High Vasopressin
The Hydration to Optimize Metabolism (H2O Metabolism) Pilot Study
This study evaluates increased hydration (1.5 L of water daily during 6 weeks) on top of habitual water intake in the lowering of the vasopressin marker copeptin and in the lowering of plasma glucose concentration in adults with…
- Trial name
- H2OMetaboPilot (NCT03574688)
- Testing
- Water
- Where
- Sweden
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Region Skane
Scars
The Effect of Hysterotomy Technique on the Rate of Large Defects in the Hysterotomy Scar
The Effect of Cesarean Operative Technique on the Occurrence of Large Hysterotomy Scar Defects.
- Trial name
- NCT01091181
- Testing
- hysterotomy at cesarean
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Region Skane
Pathogenic Bacteria in the Oropharynx, Ventilator-associated Pneumonia
Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients
Critically ill patients often need ventilatory support through a plastic tube connected to a ventilator. Those patients have a altered microbiological flora in the mouth, oropharynx as well as throughout the intestine.
- Trial name
- NCT01105819
- Testing
- Lactobacillus plantarum 299 for oral care, Chlorhexidine for standard oral care
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane
Male Infertility
Impact of Antioxidant Treatment on DNA Fragmentation Index
Increased sperm DNA Fragmentation Index implies decreased male fertility in vivo and in vitro. There is need for developing new strategies for improvement of male fertility.
- Trial name
- Androferti (NCT03466229)
- Testing
- Androferti
- Volunteers
- 79 people
- Sponsor
- Region Skane
Stress, Anxiety
Yoga and Psychological and Physiological Health
This study aims to evaluate the benefits of yoga as a 'mind-body' practice, by measuring it's effects on health-related psychological and physiological variables.
- Conditions
- Stress, Anxiety, Depression, Sleep
- Trial name
- NCT03428542
- Testing
- Yin yoga, YOMI
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Region Skane
Rectal Cancer
Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer Treatment
The aim of this study is to investigate how bacteria and fibre interact with the epithelial cells of the gastrointestinal mucosa to reduce inflammation and to diminish tissue damage caused by radiation therapy to patients…
- Trial name
- FIPIREX (NCT03420443)
- Testing
- Oat bran, Oat bran and blueberry husks, No oral supplementation
- Volunteers
- 30 people
- Sponsor
- Region Skane
Obesity, Diet Modification
Clinical Effects of Nutrition on Metabolic Risk Factors and Mechanisms
The overall aim for this study is to evaluate the clinical effects of a modified diet on metabolic risk factors such as diabetes mellitus and obesity, and the mechanisms this nutrition composition exerts on gastrointestinal…
- Trial name
- NCT02405806
- Testing
- low carbohydrate food, standard food
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Region Skane
Urinary Catheters, Retention, Urinary
Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Catheters
A randomized, open label, controlled, parallel group study to investigate difference between regional standard procedure and a novel modified procedure (using an additional novel device to facilitate gel installation) for…
- Conditions
- Urinary Catheters, Retention, Urinary, Incontinence, Urinary, Anesthesia, Local
- Trial name
- NCT03289117
- Testing
- Novel gel installation device procedure, Standard procedure
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Clostridium Difficile Colonisation, Impact of Enteral Probiotics on Certain Lab Parameters
Probiotics for Reduction of Infections With Clostridium Difficile in Critically Ill Patients
Symptoms of Clostridium difficile infection is almost always induced as a complication to the use of antibiotics. Most ICU patients are given antibiotics.
- Trial name
- ProbiEnt (NCT01687543)
- Testing
- L. plantarum 299 and L. plantarum 299v (+maltodextrin), Maltodextrin
- Where
- 4 sites in Sweden
- Volunteers
- 25 people
- Sponsor
- Region Skane
Osteoarthritis
Importance of Restoring Biomechanical Correct Hip Anatomy During Total Hip Arthroplasty
The purpose of this prospective, randomized study is to evaluate the importance of restoring the exact individual hip biomechanics during total hip arthroplasty.
- Trial name
- NCT01512550
- Testing
- GF hip guide, Stryker Navigation System, ABG II modular femoral component
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Skane
Throatcarriers of MRSA
MESS-study MRSA Eradication Study Skåne
The purpose of this study is to determine whether systemic antibiotic treatment with rifampicin and clindamycine or trimethoprim-sulfa in addition to topical treatment with mupirocin is more effective than only topical treatment…
- Trial name
- MESS (NCT01269541)
- Testing
- Mupirocin, Rifampin+Clindamycine or Trimehoprimsulfa
- Where
- 6 sites in Sweden
- Volunteers
- 69 people
- Sponsor
- Region Skane
Aseptic Loosening of the Hip Prosthesis
Bisphosphonates and Impaction Grafting in Hip Revision
The primary focus of this study is to investigate whether increased bone density of the graft in revision arthroplasty of the hip can cause a decreased micromotion of the implant relative to the femur.
- Trial name
- NCT00658268
- Testing
- Clodronate
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Glucose Intolerance
Effects of Two Doses of Thylakoids on OGTT
This cross-over intervention study aims to investigate the effect of two doses of thylakoids to an oral glucose tolerance test (OGTT) on glucose and insulin homeostasis as well as appetite regulating hormones in healthy…
- Trial name
- NCT02702245
- Testing
- Experimental: Thylakoids 5 g, Experimental: Thylakoids 10 g
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Region Skane
Rectal Cancer
MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients
To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.
- Trial name
- MMP-7 (NCT03151759)
- Testing
- Neoadjuvant radiotherapy
- Volunteers
- 77 people
- Sponsor
- Region Skane
Platelet Aggregation, Spontaneous, Atherosclerosis
Effects of Fish Oil on Platelet Function and Coagulation
Many patients undergoing surgery use naturopathic drugs, including fish oil. Fish oil has been reported to increase bleeding in patients through inhibiting platelet aggregation and prolonging of clot formation time.
- Conditions
- Platelet Aggregation, Spontaneous, Atherosclerosis, Surgery
- Trial name
- FOILP (NCT03048981)
- Testing
- Fish oil
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Region Skane
Pancreatic Neoplasms, Urogenital Neoplasm
The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgery
To study if plasma volume expansion is influenced by the rate at which a colloidal solution is administered in patients with a systemic inflammatory response induced by major abdominal surgery.
- Conditions
- Pancreatic Neoplasms, Urogenital Neoplasm, Systemic Inflammatory Response Syndrome, Hypovolemia
- Trial name
- AIR (NCT02728921)
- Testing
- 5% Albumin infusion 30 min, 5% Albumin infusion 3 hours
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Region Skane
Quality of Life, Oesophageal Cancer
Quality of Life After Oesophageal or Gastric Cancer Surgery
This study aim to assess quality of life of patients 0-5 years after oesophageal or gastric cancer surgery and to develop and test an information and support program aiming to enhance the patients quality of life (QOL) after…
- Conditions
- Quality of Life, Oesophageal Cancer, Gastric Cancer
- Trial name
- NCT01657175
- Testing
- Supportive care
- Where
- Sweden
- Volunteers
- 82 people
- Sponsor
- Region Skane