Clinical trials: sponsored by RenJi Hospital
Patients With Uncertain Difficult Airway, Colon Cancer
Safety and Feasibility of Reversible Induction Strategy
This study would explore the safety and feasibility of a reversible induction strategy for uncertain difficult airway. This reversible induction strategy would include high flow nasal canular oxygenation support, short-term…
- Conditions
- Patients With Uncertain Difficult Airway, Colon Cancer, Gastric Cancer, Prostatic Cancer
- Trial name
- NCT04434963
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Acute-On-Chronic Liver Failure, Liver Cirrhosis
Transplantation for EASL-CLIF and APASL ACLF Patients: a Retrospective Cohort Study
The definition and diagnostic criteria of acute-on chronic liver failure (ACLF) differed evidently between the East and the West due to the difference in the underlying etiology.
- Conditions
- Acute-On-Chronic Liver Failure, Liver Cirrhosis, Liver Transplant; Complications
- Trial name
- TEA-ACLF (NCT05036031)
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Lung Cancer, Lung Adenocarcinoma
Identify Prognostic Biomarkers of Lung Cancer
Multi-omics and Clinical Data Analysis is potential to predict the prognosis of lung cancer patients.
- Conditions
- Lung Cancer, Lung Adenocarcinoma, Lung Squamous Cell Carcinoma, Non Small Cell Lung Cancer
- Trial name
- NCT05010330
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Diabetes Mellitus
Establishment and Preliminary Evaluation of Digital Three Level Linkage Whole Process Diabetes Management System
This study used Nan'an District of Chongqing, China as a pilot project to improve the comprehensive compliance rate of diabetic patients in China, and reduce the physical and economic harm caused by complications.
- Trial name
- NCT04999722
- Testing
- Traditional mode of management, Mobile APP management
- Volunteers
- 1,200 people
- Sponsor
- Chongqing Renji Hospital, University of Chinese Academy of Sciences
Bladder Cancer
Influence of Opioids on Circulating Tumor Cells in Radical Cystectomy
Multiple lines of evidence have shown that perioperative opioids requirement was associated with poor outcomes in cancer patients, including increased cancer progression and metastases and reduced survival in patients with lung…
- Trial name
- NCT04358718
- Testing
- general anesthesia, general anesthesia combined with epidural analgesia
- Where
- China
- Volunteers
- 44 people
- Sponsor
- RenJi Hospital
Lupus Nephritis
Urine Exosomes to Identify Biomarkers for LN
Urine exosomes will be extracted from patients with lupus nephritis, healthy controls, and patients with systemic lupus erythematosus without lupus nephritis.
- Trial name
- NCT04894695
- Testing
- biomarkers detection in different groups
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Hepatic Artery Thrombosis, Liver Transplant; Complications
Ticagrelor in Post-transplant Patients With Pediatric Hepatic Artery Thrombosis (HAT)
Hepatic artery thrombosis (HAT) represents a major cause of graft loss and mortality after Pediatric liver transplantation. Ticagrelor (a new reversible inhibitor of P2Y12 receptor with faster onset of action and greater platelet…
- Conditions
- Hepatic Artery Thrombosis, Liver Transplant; Complications, Pediatric Disease
- Trial name
- Tip-HAT (NCT04946929)
- Testing
- Ticagrelor Oral Tablet [Brilinta], Low molecular weight heparin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma Recurrent, Liver Transplant; Complications
Heterogeneity and Evolution of hepatoceLlular Carcinoma in Post-transplant HCC Recurrence
Objective of Study: This study will evaluate the heterogeneity and evolution pathway between primary HCC and tumor relapse after liver transplant.
- Trial name
- HELP-2020 (NCT04506398)
- Testing
- liver transplant, ctDNA, whole exome sequencing
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Urinary Bladder Neoplasms, Urologic Neoplasms
Safety and Efficacy Study of Tislelizumab in Combination With BCG in HR-NMIBC Patients (TACBIN-01)
This study is a single-arm, open-label, single-center study to assess the safety of tislelizumab with BCG, and to obtain the preliminary efficacy results in subjects who have been diagnosed with high-risk NMIBC without prior BCG…
- Conditions
- Urinary Bladder Neoplasms, Urologic Neoplasms, Urogenital Neoplasms, Antineoplastic Agents
- Trial name
- TACBIN-01 (NCT04922047)
- Testing
- tislelizumab and BCG
- Where
- China
- Volunteers
- 6 people
- Sponsor
- RenJi Hospital
Cardiology
Comprehensive CT-guided vs Echo-fluoroscopy-guided Strategy in the Left Atrial Appendage Occlusion
Percutaneous left atrial appendage occlusion (LAAO) is an increasingly used alternative to oral anticoagulation in patients with nonvalvular atrial fibrillation (AF).
- Trial name
- NCT04913207
- Testing
- method of device size selection
- Where
- China
- Volunteers
- 310 people
- Sponsor
- RenJi Hospital
Immune System and Related Disorders
COVID-2019 Vaccine Immune Response Base on Single Cell Multi-Omics
In recent years, single-cell high-throughput sequencing technology has developed rapidly and is widely used in research related to the immune system, breaking traditional cognition and gaining a new understanding of immune cell…
- Trial name
- NCT04871932
- Testing
- Recently Vaccination
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Peritoneal Dialysis
Understand the Association Between Peritoneal Dialysis Status and Gene Polymorphisms of VEGF and KDR
Peritoneal dialysis (PD) is an effective and successful way of renal replacement therapy. The initial transport status is related to distribution of blood vessels and micro inflammation state in peritoneum before PD.
- Trial name
- NCT04888065
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Acute Coronary Syndrome
Serum Soluble ST2 and Plaque Vulnerability in Patients With Acute Coronary Syndrome
This study aimed to assess the association between serum sST2 level and plaque vulnerability in ACS patients. It is hypothesized that serum sST2 level may be related to plaque components and closely associated with plaque…
- Trial name
- NCT04797819
- Testing
- Coronary plaque components
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Adverse Maternal and Neonatal Outcomes
Risk Factors for Pregnancy-induced Hypertension in Pregnant Patients Undergoing Cesarean Section
After Institutional Review Board approval, we performed a retrospective cohort study among all women presenting for pregnancy-induced hypertension under Cesarean section in Renji Hospital Affiliated to Shanghai Jiaotong…
- Trial name
- NCT04808375
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- RenJi Hospital
Liver Cirrhosis
Clinical Study of Hepatocyte Transplantation for Liver Cirrhosis
The Primary Objective: To observe and determine the safety and tolerance of allogeneic hepatocyte transplantation in patients with liver cirrhosis and to establish the maximum-tolerated dose (MTD) and evaluate the dose-limiting…
- Trial name
- NCT04806581
- Testing
- Allogeneic Hepatocyte
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Type2 Diabetes, Polycystic Ovary Syndrome
Myocardial Pathological Changes in Patients of Type 2 Diabetes With or Without PCOS Using Cardiac Magnetic Resonance
The study is prepared to use CMR technology for early screening of myocardial lesions in 561 age-matched women with type 2 diabetes without PCOS, with PCOS without type 2 diabetes and with type 2 diabetes combined with PCOS…
- Trial name
- NCT04805853
- Where
- China
- Volunteers
- 561 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Peritoneal Dialysis
Understand the Difference Between Clinical Measured UF and Real UF.
The importance of ultrafiltration (UF) and fluid status in peritoneal dialysis has been increasingly aware of over the last two decades.
- Trial name
- NCT03864120
- Where
- China
- Volunteers
- 261 people
- Sponsor
- RenJi Hospital
Functional Gastrointestinal Disorders, Adherence, Patient
Impact of Stigma on Compliance to Medication in Functional Dyspepsia
To date, no study exists that evaluates whether functional dyspepsia patients experience stigma and how stigma may influence adherence.
- Trial name
- NCT03625674
- Testing
- explanation when prescribing psychoactive medicine
- Where
- China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Acute Coronary Syndrome
Pericoronary Fat Attenuation Index and High-risk Plaque in Patients With Acute Coronary Syndrome
This study aimed to investigate the relationship between CCTA-based pericoronary inflammation and plaque features as well as local immune-inflammatory biomarkers in ACS patients.
- Trial name
- NCT04792047
- Testing
- HRP frequency, plaque compostion and local immune-inflammatory activation
- Where
- China
- Volunteers
- 130 people
- Sponsor
- RenJi Hospital
Rheumatic Diseases
The Effect of OPCSP on Adherence and Clinical Outcomes Among Patients With Rheumatic Diseases
This is a randomised trial on the efficacy of an Outpatient Pharmacy Clinical Services Program (OPCSP) on adherence and clinical outcomes among patients with rheumatic diseases.The purpose of this study is to evaluate: 1.
- Trial name
- NCT03024307
- Testing
- pharmacists involved OPCSP
- Where
- China
- Volunteers
- 242 people
- Sponsor
- RenJi Hospital