Clinical trials: sponsored by RenJi Hospital
ST-Segment Elevated Myocardial Infarction
Early rhBNP on Myocardial Work in Patients With STEMI
The study intends to evaluate the efficacy of early rhBNP on myocardial work in patients with anterior ST-segment elevation myocardial infarction after percutaneous coronary intervention
- Trial name
- NCT04157868
- Testing
- rhBNP, Control
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Early Gastric Cancer
Laparoscopy-assisted Pylorus-vagus Nerve Preserving Gastrectomy in the Treatment of Early Gastric Cancer
The safety and efficacy of Laparoscopy-assisted Pylorus-preserving Gastrectomy (LAPPG) for the treatment of early gastric cancer (EGC) remain controversial.
- Trial name
- LAPPG (NCT02936193)
- Testing
- Pylorus preservation, Distal gastrectomy
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Severe Obesity
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
This is a experimental study, which subjects are obese PCOS patients requiring LSG surgery. Aim to investigate the effects of LSG surgery in PCOS patients whether increases the live birth rate of the offspring.
- Conditions
- Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT04151459
- Testing
- Metformin
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
Lupus Nephritis
Metformin In Prevention of Lupus Nephritis
Lupus nephritis (LN) is a main manifestation of systemic lupus erythematosus (SLE), which will largely effect the prognosis of SLE patients.
- Trial name
- NCT04145687
- Testing
- Metformin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Biliary Tract Neoplasms
The Effect of Individualized Precision Therapy Programs in Patients With BTC
This is a prospective cohort study. Patients who meet the inclusion criteria will be enrolled in this study. The samples of biliary tract tumors will be collected.
- Trial name
- NCT02943031
- Testing
- Individualized Precision Therapy Programs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Biliary Tract Neoplasms
The Role of ctDNA and PBMC in Treatment of Biliary Tract Cancer
Our study aims to evaluate the role of ct-DNA and PBMC as biomarkers in the treatment of biliary tract cancer.
- Trial name
- NCT02809898
- Testing
- surgery or biopsy
- Where
- 4 sites in China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Intravesical Instillation
Single Versus Long-term Intravesical Instillation Chemotherapy for Recurrence After Nephroureterectomy for Upper Tract Urothelial Carcinoma
Up to 30-40% of the patients may develop bladder recurrance after radical nephroureterectomy for primary upper tract urothelial carcinoma.
- Trial name
- NCT03030157
- Testing
- pirarubicin(THP)
- Where
- China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Systemic Lupus Erythematosus
The Effect of Metformin on Reducing Lupus Flares
This is a multicenter, randomised, double-blind placebo controlled trial on the efficacy and safety of add-on metformin to conventional immunosuppressants in systemic lupus erythematosus (SLE).
- Trial name
- Met Lupus (NCT02741960)
- Testing
- metformin
- Where
- China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Overweight and Obesity
Research of Exenatide for Overweight/Obese PCOS Patients With IGR
Compare the therapeutic effects of exenatide, metformin and their combination for 3 months on reproductive and metabolic improvements of overweight/obese PCOS patients with impaired glucose regulation.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Disorder of Glucose Regulation
- Trial name
- NCT03352869
- Testing
- Exenatide, Metformin
- Where
- China
- Volunteers
- 183 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma
CAR-GPC3 T Cells in Patients With Refractory Hepatocellular Carcinoma
This study is designed to determine the safety and efficacy of CAR-GPC3 T cells in patients with relapsed or refractory hepatocellular carcinoma.
- Trial name
- NCT03146234
- Testing
- CAR-GPC3 T cells
- Where
- China
- Volunteers
- 7 people
- Sponsor
- RenJi Hospital
Hepatocellular Carcinoma
Anti-GPC3 CAR T for Treating Patients With Advanced HCC
The purpose of this study is to determine whether autologous T cells bearing chimeric antigen receptor that can specifically recognize glypican-3 (GPC3) is safe and effective for patients with relapsed or refractory…
- Trial name
- NCT02395250
- Testing
- anti-GPC3 CAR T
- Where
- China
- Volunteers
- 13 people
- Sponsor
- RenJi Hospital
Undifferentiated Connective Tissue Disease, Recurrent Pregnancy Loss
Immunosuppressant Regimens for Living Fetuses Study
Undifferentiated connective tissue diseases (UCTD) are known to increase the risk of pregnancy morbidities, including recurrent pregnancy loss.
- Trial name
- NCT03671174
- Testing
- Prednisone, Hydroxychloroquine, Aspirin
- Where
- China
- Volunteers
- 420 people
- Sponsor
- RenJi Hospital
Pulmonary Arterial Hypertension
Long-term Outcomes of Pregnant Women With PAH
The investigators intend to explore the characteristics and outcomes of pregnant women with PAH during different pregnancies and to provide applicable evidence for clinical practice.
- Trial name
- NCT04053296
- Testing
- Observational study
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Functional Gastrointestinal Disorders, Patient Compliance
SMS Reminders and Treatment Compliance and Efficacy in Patients With FGIDs
The effect of SMS follow-up on drug compliance and efficacy in patients with FGIDs has not been reported in the literature. We, therefore, conducted a prospective randomized controlled trial to investigate whether SMS follow-up…
- Trial name
- NCT04052750
- Testing
- SMS follow-up
- Where
- China
- Volunteers
- 176 people
- Sponsor
- RenJi Hospital
Hypoxia, Hypercapnia
Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange
For performing transnasal humidified rapid insufflation ventilatory exchange (THRIVE), jaw-thrust maneuver have to maintain to make sure the airway open and the CO2 clearance during apnoea.
- Trial name
- NCT03741998
- Testing
- Nasopharyngeal airway
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
EARLY-MYO-CMR-II Registry
The purpose of this registry is to depict the myocardial tissue characteristics in NSTEMI patients by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices.
- Trial name
- NCT03995433
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Infertility
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Ovulation Disorder
- Trial name
- NCT03989024
- Testing
- Gonadorelin, Clomiphene
- Where
- China
- Volunteers
- 78 people
- Sponsor
- RenJi Hospital
Cognitive Dysfunction
Transcutaneous Electrical Stimulation of the Vagus Nerve
This study evaluate the cognitive functions of patient after hip or kneel replacement.Half of the patient will receive transcutaneous vagus nerve electrical stimulation during the surgery while the other half will get placebo…
- Trial name
- TESVNR (NCT03989375)
- Testing
- transcutaneous vagus nerve electric stimulator
- Where
- China
- Volunteers
- 110 people
- Sponsor
- RenJi Hospital
Necrosis of Femoral Head, Knee Osteoarthritis
CSF Cholinergic Biomarkers and Postoperative Cognitive Change
Previous study demonstrated that the condition of central cholinergic nerve is important for the postoperative cognitive dysfunction.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Lower Limb
- Trial name
- NCT02063542
- Where
- China
- Volunteers
- 102 people
- Sponsor
- RenJi Hospital
Perioperative Antihypertensive
Antihypertensives in Non-cardiac Surgical Population
A cohort of hypertension patients undergoing elective non-cardiac surgery was constructed to investigate current status of antihypertensive drug treatment in non-cardiac surgical population.
- Trial name
- NCT03953872
- Where
- China
- Volunteers
- 351 people
- Sponsor
- RenJi Hospital