Clinical trials: sponsored by RenJi Hospital
Gastrointestinal Stromal Tumor
Serum Dickkopf-4 as a Biomarker for the Diagnosis and Treatment of Gastrointestinal Stromal Tumor
Our study aims to evaluate the role of Dickkopf-4 as biomarkers in the treatment of gastrointestinal stromal tumor.
- Trial name
- NCT02931981
- Testing
- surgery or biopsy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- RenJi Hospital
Renal Cell Carcinoma
Robot-Assisted Laparoscopic Radio Frequency Ablation Assisted Enucleation of Renal Cell Carcinoma With T1a Stage
To evaluate the feasibility and efficiency of zero ischemia robot-assisted laparoscopic radio frequency ablation assisted enucleation of T1a renal cell carcinoma in comparison with robot-assisted laparoscopic partial nephrectomy…
- Trial name
- NCT02924597
- Testing
- zero ischemia robot-assisted laparoscopic RFA assisted TE, zero ischemia robot-assisted laparoscopic partial nephrectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Dermatopolymyositis, Interstitial Lung Disease
Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis
Interstitial lung disease (ILD) is a common complication of dermatomyositis (DM) with prevalence up to 65%, and is considered to be one of the determining factors of prognosis.
- Trial name
- NCT02821689
- Testing
- Pirfenidone
- Where
- China
- Volunteers
- 57 people
- Sponsor
- RenJi Hospital
Anesthesia, Incarcerated Inguinal Hernia
Safety and Efficacy of Local Anesthesia in Emergency Inguinal Hernia Surgery
This prospective randomized is designed to evaluate the safety and efficacy of hernia repairs using local anesthesia compared with those using general anesthesia for patients with incarcerated hernia.
- Trial name
- NCT02599623
- Testing
- Local Anesthesia, General Anesthesia
- Where
- China
- Volunteers
- 80 people
- Sponsor
- RenJi Hospital
Kidney Neoplasms
Zero Ischemia Laparoscopic Radio Frequency/Microwave Ablation Assisted Enucleation of Renal Cell Carcinoma With T1 Stage
Zero ischemia laparoscopic radio frequency ablation assisted tumor enucleation has been proved to enable tumor excision with relatively better renal function preservation comparing with conventional laparoscopic partial…
- Trial name
- NCT02734329
- Testing
- conventional laparoscopic partial nephrectomy, zero ischemia laparoscopic RFA/MVA assisted tumor enucleation (TE)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Cardiac Output,Low, Hemodynamic Instability
Cardiac Output Changes in Cesarean Section
Since 2011, phenylephrine was recommended as the preferred drug to maintain blood pressure in obstetric anesthesia.Phenylephrine, an α adrenoceptor agonist, can induce peripheral vasoconstriction to maintain blood pressure, while…
- Conditions
- Cardiac Output,Low, Hemodynamic Instability, Obstetrical Complication of Anesthesia
- Trial name
- NCT02759510
- Testing
- Norepinephrine, Phenylephrine
- Volunteers
- 106 people
- Sponsor
- RenJi Hospital
Brain Injuries, Traumatic
Pre-hospital Administration of Tranexamic Acid for Moderate and Severe Traumatic Brain Injury
This study is a prospective single-centre randomized trial to compare the effect of tranexamic acid versus placebo in the pre-hospital management of patients with moderate and severe traumatic brain injury.
- Trial name
- NCT02645552
- Testing
- Tranexamic Acid, Sodium chloride
- Where
- China
- Volunteers
- 400 people
- Sponsor
- RenJi Hospital
TBI (Traumatic Brain Injury)
Asia Coma Electrical Stimulation (the ACES Trial)
This study is a prospective multicenter randomized controlled trial from Asian countries to compare the effect and safety of right median nerve stimulation versus traditional treatment for comatose patients at the early stage…
- Trial name
- ACES (NCT02645578)
- Testing
- Right median nerve stimulation
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Ischemic
Exploratory Study on the Effects of Early Rosuvastatin Treatment in Patients With Acute Ischemic Stroke
This is an exploratory, randomized, open-label, 2-arm, parallel-group study exploring the efficacy of rosuvastatin (20mg/day) in patients with acute ischemic stroke.
- Trial name
- AIS (NCT02643784)
- Testing
- Rosuvastatin, Control
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Evidence of Liver Transplantation
Clinical Trial of Hydrogen-Rich Celsior Solution Applied in Aging DBD Liver/Kidney Transplantation
The purpose of this study is to investigate whether hydrogen-rich Celsior solution improve the quality of aging grafts in liver/kidney transplantation.
- Trial name
- HRCSDBD (NCT02613195)
- Testing
- Hydrogen-Rich Celsior Solution
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Platelet Count/Spleen Diameter Ratio, Child-Pugh Classification
Platelet Count（PC）/Spleen Diameter(SD) Ratio to Predict the Variceal Haemorrhage in HBV Cirrhotic Patients in China
To validate the PC/SD ratio to be used to predict the variceal haemorrhage in Chinese patients with hepatitis B virus (HBV)-associated hepatic cirrhosis.
- Trial name
- NCT02546414
- Testing
- Platelet count/spleen diameter ratio
- Where
- China
- Volunteers
- 150 people
- Sponsor
- RenJi Hospital
Biliary Atresia, Metabolic Disorders
Clinical and Basic Study for Pediatric Liver Transplantation
Background: In mainland China, the development of pediatric liver transplantation (LT) has lagged behind that of adult LT during the past two decades, but it has been progressing immensely in recent years.
- Conditions
- Biliary Atresia, Metabolic Disorders, Fulminant Liver Failure, Hepatic Tumors
- Trial name
- CBSPLT (NCT02503384)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Atrial Fibrillation
a Novel Individualized Substrate Modification Approach for the Treatment of Long-standing Persistent Atrial Fibrillation
The purpose of this study is to compare effectiveness of two substrate modification approaches in long-standing persistent atrial fibrillation patients, and hypothesized that a substrate-based, individualized substrate…
- Trial name
- NCT02477592
- Testing
- individualized substrate modification, stepwise ablation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Tumor Recurrence and Metastasis
the Influence of General Anesthesia on Tumor Metastasis and Recurrence
The purpose of this study was to investigate whether general anesthesia will affect the postoperative recurrence and metastasis of malignant tumor.
- Trial name
- NCT02474511
- Testing
- general anesthesia and local anesthesia
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Hypertension, Hemodynamic Instability
Perioperative Baroreflex Sensitivity
Impaired baroreflex sensitivity (BRS) is a marker of autonomous dysfunction, which may play an important role in the long-term development of hypertension.
- Conditions
- Hypertension, Hemodynamic Instability, Surgery
- Trial name
- NCT02435875
- Testing
- no intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Peptic Ulcer, Gastric Cancer
WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy
Low pulse oximetry is the most common adverse events during sedation for upper gastrointestinal endoscopy. The main reason is the glossoptosis after sedation.
- Conditions
- Peptic Ulcer, Gastric Cancer, Esophagus Cancer, Oesophagitis
- Trial name
- NCT02436018
- Testing
- WEI NASAL JET, Nasopharyngeal airway without jet ventilator
- Where
- 3 sites in China
- Volunteers
- 1,800 people
- Sponsor
- RenJi Hospital
Dyspepsia, Compliance
Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
The study hypothesis is appropriate clinician-patient communication that provides explanations of the reasons for psychoactive drug prescriptions based on the generation of FD symptoms and the drugs' effects might improve…
- Conditions
- Dyspepsia, Compliance, Depression
- Trial name
- NCT01851863
- Testing
- Omeprazole, Flupentixol-Melitracen(psychological and GI) + Omeprazole, Flupentixol-Melitracen(psychological) + Omeprazole
- Where
- China
- Volunteers
- 262 people
- Sponsor
- RenJi Hospital
Advanced Glioma
CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR
The purpose of this study is to determine whether autologous T cells bearing chimeric antigen receptor that can specifically recognize EGFR overexpressed in tumor cells is safe and effective for patients with EGFR-overexpressing…
- Trial name
- NCT02331693
- Testing
- anti-EGFR CAR T
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
We Focus on the Pain of Venipuncture and Intravenous Cannulation
Lidocaine Patches for Attenuating the Pain of Venipuncture Intravenous Cannulation
Venipuncture and intravenous cannulation are the most common painful procedures, especially for the penitents who must receive large diameter venous catheter before surgery.
- Trial name
- NCT02061475
- Testing
- Lidocaine Patches
- Where
- 8 sites in China
- Volunteers
- 240 people
- Sponsor
- RenJi Hospital
Necrosis of Femoral Head, Knee Osteoarthritis
Ketamine Prevent POCD
Previous study demonstrated that neuroinflammation induced by surgery is the main cause of the postoperative cognitive dysfunction. As an agonist of NMDA receptor, ketamine is proved to be an anti-inflammation agent.
- Trial name
- KPPOCD (NCT02220400)
- Testing
- Ketamine
- Where
- 3 sites in China
- Volunteers
- 484 people
- Sponsor
- RenJi Hospital