Clinical trials: sponsored by Rennes University Hospital
Anesthesia, Opioid-Related Disorders
Postoperative and Opioid Free Anesthesia
Since the 1960's, intraoperative administration of opioids is considered a keystone of anesthesia as well as hypnotics and muscle relaxants. Synthetic opioids were introduced to achieve hemodynamic stability during anesthesia.
- Trial name
- POFA (NCT03316339)
- Testing
- Dexmedetomidine, Remifentanil
- Where
- 11 sites in France
- Volunteers
- 316 people
- Sponsor
- Rennes University Hospital
Pubic and Abdominal Pathology
Shortystrap Effectiveness in the Treatment of the Pathology Pubic and Abdominal Pathology in Athletes
The pubic and abdominal pathology is common among athletes. It leads to a shutdown of physical activity for several months, and requires rehabilitative care, or surgery for a permanent cure.
- Trial name
- Shortystrap (NCT02882399)
- Testing
- Shortystrap
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Rennes University Hospital
Unilateral Spastic Cerebral Palsy
"Be an Airplane Pilot": A Bimanual 3D Motion Analysis in Children With Unilateral Cerebral Palsy
Cerebral Palsy, in particular in its unilateral spastic form (uCP), is the main cause of motor disability in children, with a prevalence of 2/1000 births.
- Trial name
- BE-API (NCT03888443)
- Testing
- Bimanual 3D Motion Analysis " Be-API "
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Carotid Stenosis
Carotid Region Calcifications and Orthopantomogram
Observational study.
- Trial name
- ADCACO (NCT03936881)
- Where
- France
- Volunteers
- 401 people
- Sponsor
- Rennes University Hospital
Hemochromatoses, Genetic
Transferrin Saturation and Asthenia in Hemochromatosis
Observational study.
- Trial name
- HEMOSAT (NCT03356548)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Rennes University Hospital
French Vascular Physicians
Arterial Doppler Waveforms Analysis in PAD
The main objective is to evaluate the differences of terminology used when describing arterial doppler waveforms. To assess the impact of an educational process
- Trial name
- APP-Wave-PAD (NCT03827512)
- Testing
- Doppler arterial waveforms analysis
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
ARDS, Human
Study of the Effects of Bronchoalveolar Lavage Liquid in the ARDS on the Functioning of the Neutrophil Polynuclear System
Firstly, the study assesses the effect of bronchoalveolar lavage fluid (BAL) from patients in (acute respiratory distress syndrome (ARDS) on the life span of PNNs and on the phagocytosis of apoptotic cells by macrophages and…
- Trial name
- BALARDS (NCT04008225)
- Testing
- Bronchoalveolar lavage
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Rennes University Hospital
Fusion Imaging for EVAR
Fusion Imaging for EVAR With Mobile C-arm
Fusion imaging is a technique that facilitates endovascular navigation but is only available in hybrid rooms. The goal of this study is to evaluate the feasibility of fusion imaging with a mobile C-arm in a conventional operating…
- Trial name
- FUTUR (NCT04008212)
- Testing
- Fusion imaging
- Volunteers
- 59 people
- Sponsor
- Rennes University Hospital
Crohn Disease
Junior / Senior Concordance in Ultrasound Assessment of Crohn's Disease
Observational study
- Trial name
- ECHOCROHN (NCT03439826)
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Rennes University Hospital
Emergencies
Population Pharmacokinetics of Amoxicillin in Neonates
The objective of NEOPOPI is to conduct a population pharmacokinetic study of amoxicillin in neonates, in order to evaluate and optimize neonatal dose regimen.
- Trial name
- NEOPOPI (NCT03987100)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Rennes University Hospital
Surgical Procedure, Unspecified
Intraoperative Fluorescence of Ganglogliomas and Neuroepithelial Dysembryoplastic Tumors
One of the key issues of tumour brain surgeries is to clearly define the borders of the tumor. The investigators proposed to evaluate the feasibility of intraoperative fluorescein guidance.
- Trial name
- FLUOGOD (NCT03970785)
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Rennes University Hospital
Hepatocellular Carcinoma
Transarterial Chemoembolization Prior to Transplantation for Hepatocellular Carcinoma
The hope to treat more patients with hepatocellular carcinoma successfully is however tempered by the shortage of donors leading to an increasing waiting time for liver transplantation (LT).
- Trial name
- CATCH (NCT01676194)
- Testing
- Intra-arterial administration of DC BeadsR
- Where
- 7 sites in France
- Volunteers
- 7 people
- Sponsor
- Rennes University Hospital
Hemochromatosis, Type 4, Ferroportin Disease
Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.
The diagnosis of iron overload is a common problem. It is important to optimize the diagnosis to ensure support for patients and their relatives especially regarding genetic disease.
- Conditions
- Hemochromatosis, Type 4, Ferroportin Disease, Dysmetabolic Hepatosiderosis, Diagnosis
- Trial name
- NCT01949467
- Testing
- iron fumarate
- Where
- 4 sites in France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Acute Alcohol Intoxication
Evaluation of a Personalized Normative Feedback Repeatedly Delivered Via a Mobile Application After a Brief Therapeutic Intervention on Alcohol-related Risks:
BTI (Brief Therapeutic Intervention) motivates individuals admitted to ED (Emergency Department) for acute intoxication to take actions to prevent further alcohol-related issues.
- Trial name
- IFACAP (NCT03059628)
- Testing
- Personalized Normative Feedback, Brief Therapeutic Intervention, Evaluation questionnaire
- Where
- 5 sites in France
- Volunteers
- 222 people
- Sponsor
- Rennes University Hospital
Chronic Heart Failure
Effects of Amlodipine in the Management of Chronic Heart Failure
Patients with congestive heart failure are usually treated with a combination of an ACE inhibitor (or an AT1 blocking agent), a diuretic and a beta-blocker.
- Trial name
- NCT00151619
- Testing
- Amlodipine
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- Rennes University Hospital
Myocardial Function of the Stenosis Aortic Valve Before and Beyond Valve Replacement
Myocardial Function of the Setonis Aortic Valve Before and Beyond Valve Replacement
Study the consequences on heart muscle of the stenosis aortic valve before and after the replacement procedure, the repercussion on heart.
- Trial name
- AOMYOC (NCT03686527)
- Testing
- stenosis aortic valve
- Where
- France
- Volunteers
- 277 people
- Sponsor
- Rennes University Hospital
Venous Thrombosis or Pulmonary Embolism
What Treatment for Patients With Phlebitis or Pulmonary Embolism ?
The objective of the "anticoagchoice" study is to analyze the preferences of people suffering from phlebitis, in terms of anticoagulant, to improve adherence to these treatments, to adapt the medical prescriptions.
- Trial name
- AntiCoagChoice (NCT03889457)
- Testing
- anticoagulation choice
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Rennes University Hospital
Persons Requesting a Resource Allocation (APA), Beneficiairies Requesting a Resource Allocation (APA)
Identification of Difficulties During a First Request for a Personal Autonomy Allowance
The objective of this study is to identify the difficulties when first applying for a first Resource Allocation (Personal autonomy allowance - APA) by beneficiaries and their relatives through a qualitative study and secondarily…
- Trial name
- IDAPA (NCT03877380)
- Testing
- semi-structured interview
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Anal Fistula, Crohn Disease
Management of Anal Fistula of Crohn Disease
The management of anal fistula in Crohn Disease is complex. In aim to obtain the healing of the anal fistula, different approaches can be proposed but the best strategy is not yet determined.
- Trial name
- FISTUCROHN (NCT03878498)
- Testing
- therapeutic management
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Rennes University Hospital
Refractory Hemochromatosis Rheumatism
Treatment of Refractory Hemochromatosis Rheumatism by Anakinra: a Preliminary Phase II Study
Treatment of refractory hemochromatosis rheumatism by Anakinra. Prospective, multicenter, non-randomised, single-arm, open-label, phase II trial.
- Trial name
- THERA (NCT02263638)
- Testing
- Anakinra
- Where
- 3 sites in France
- Volunteers
- 17 people
- Sponsor
- Rennes University Hospital