Clinical trials: sponsored by Research Inc
Leadership in Early Care and Education Centers
Early Care and Education Leadership Study: Descriptive Study
Mathematica and the Institute for Early Education Leadership and Innovation at the University of Massachusetts Boston, conducted a descriptive study within the Early Care and Education Leadership Study (ExCELS).
- Trial name
- ExCELS (NCT05258994)
- Where
- United States
- Volunteers
- 1,164 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Hypoxemia
Accuracy of Pulse Oximeters With Profound Hypoxia
The goal of this clinical trial is the acquisition of photoplethysmography signals during periods of profound hypoxia. The study is designed in accordance with ISO 80601- 2-61,2ed:2017-12 \& 2018-02.
- Trial name
- NCT06022523
- Testing
- Data acquisition using DT-400 pulse oximetry system
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Consolidated Research, Inc.
Squamous Cell Cancer, Squamous Cell Carcinoma
Topical Ascorbic Acid for Treatment of Squamous Cell Skin Cancer
Randomized comparative trial of a 30% solution of ascorbic acid in 95% dimethylsulfoxide applied topically twice a day for 8 weeks vs 5% imiquimod cream in the treatment of biopsy proven squamous cell carcinomas of the skin in…
- Conditions
- Squamous Cell Cancer, Squamous Cell Carcinoma, Skin Cancer, Non-melanoma Skin Cancer
- Trial name
- NCT05932511
- Testing
- 30% ascorbic acid in DMSO
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Center for Biomedical Research, Inc.
Opioid-use Disorder, Amphetamine Use Disorders
Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder
Chronic drug addiction is not only associated with increased mental health symptoms, such as anxiety and depression, but also with brain (neural and cognitive) deficits.
- Trial name
- NEAT (NCT03922646)
- Testing
- Neurocognitive Empowerment for Addiction Treatment (NEAT), Active Control
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Stress, Psychological
TU Tough: Mental Toughness Training for College Success
The aims of this study are to (1) assess the extent of psychological distress for incoming first-year students at the University of Tulsa (Part 1), (2) assess the impact of "mental toughness" training on the trajectory of…
- Trial name
- TUtough (NCT02982070)
- Testing
- Mental Toughness Training
- Where
- 2 sites in United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression, Anxiety
Latent Structure of Multi-level Assessments and Predictors of Outcomes for Women in Recovery
In this study the investigators will seek to improve their understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of trauma, mood, substance use, and eating…
- Conditions
- Depression, Anxiety, Eating Disorders, Drug Use Disorders
- Trial name
- NCT02601495
- Testing
- Women in a court diversion program
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Rheumatoid Arthritis
Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis
The primary objective of this study is to assess if there is a significant difference in the mean disease activity score in individuals with RA participating in a dietary intervention compared to those in the control group…
- Trial name
- RA-Diet (NCT05291299)
- Testing
- Anti-inflammatory diet, Control/Standard of Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Attune Health Research, Inc.
Opioid-use Disorder
Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder
Opioid use disorder (OUD) is among the costliest and deadliest substance use disorders (SUDs) in the US and world-wide. Opioids were involved in 42,249 deaths in the US in 2016, which were more than deaths due to road accidents…
- Trial name
- FPS_Opioid (NCT03907644)
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Plantar Fasciitis
Topical Phytoterpenes for Plantar Fasciitis
Randomized controlled trial of mixture of essential oils containing tea tree oil, rosemary, clove, pepper, in a formulation with skin permeation enhancers including limonene for the treatment of plantar fasciitis in adult men and…
- Trial name
- NCT05467631
- Testing
- Topical oil application
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Center for Biomedical Research, Inc.
Infectious Diseases, Bacterial Infections
A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple intravenous doses of BWC0977 when administered to healthy adult volunteers.
- Trial name
- NCT05088421
- Testing
- BWC0977
- Where
- Australia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bugworks Research Inc.
Aging, Covid19
What Works to Get the Elderly Vaccinated Against COVID-19? Experimental Evidence From India
COVID-19 poses a substantial risk to elderly populations; understanding how to get elders vaccinated against the virus is therefore a policy priority.
- Trial name
- NCT04870593
- Testing
- Information, Buddy, Gossip intervention
- Where
- India
- Volunteers
- 3,006 people
- Sponsor
- National Bureau of Economic Research, Inc.
Psoriasis Vulgaris, Active Psoriatic Arthritis
Effect of Bimekizumab in Patients With Psoriasis Vulgaris and Active Psoriatic Arthritis
This is an open-label study to evaluate the effects of bimekizumab in patients with psoriasis vulgaris and who also have active psoriatic arthritis (PsA).
- Trial name
- NCT05499416
- Testing
- Bimekizumab
- Sponsor
- Innovaderm Research Inc.
Pregnancy Prevention
A Study to Evaluate the Effect of a Contraceptive Vaginal Ring LSP- 5415 on Ovarian Function in Healthy Adult Females
The primary objective of this study is to evaluate the inhibition of ovulation in Cohort #1 (Body Mass Index of ≥ 18 kg/m2 to ≤ 30 kg/m2) after contraceptive vaginal ring LSP-5415 application for 3 treatment cycles.
- Trial name
- NCT05360550
- Testing
- LSP-5415
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lupin Research Inc
Depression, Anxiety
Cognitive Process-based Real-time fMRI Neurofeedback in MDD and Rumination
The purpose of this study is to assess the feasibility and efficacy of real-time fMRI neurofeedback for rumination.
- Trial name
- CNF-rumination (NCT04941066)
- Testing
- Active neurofeedback
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
PTSD, Cognitive Function
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Deficits in emotional cognitive control are present in a number of clinical psychiatric populations including depression, anxiety, and PTSD.
- Trial name
- SPrC-PTSD (NCT04543513)
- Testing
- Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
- Where
- United States
- Sponsor
- Laureate Institute for Brain Research, Inc.
Healthy Volunteers, Cognitive Function
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control
Deficits in emotional cognitive control are present in a number of clinical psychiatric populations including depression, anxiety, and PTSD.
- Trial name
- SPrC (NCT04543500)
- Testing
- Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Diabetes Mellitus, Type 2
Canagliflozin-Mealtime Insulin Rescue
24-week, randomized, double blind, placebo-controlled trial to evaluate safety and efficacy of canagliflozin as compared with placebo in reducing the need for mealtime insulin in subjects with type 2 diabetes currently using a…
- Trial name
- NCT02624908
- Testing
- canagliflozin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Foundation for Atlanta Veterans Education and Research, Inc.
PTSD, Anxiety
Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
The primary objective of this study is to collect insights from first responders and military personnel on their need for, use of, and interest in physical and/or mental health medical marijuana or psychedelic-assisted therapy…
- Conditions
- PTSD, Anxiety, Anxiety Disorders, Depression
- Trial name
- EMPOWER (NCT04965740)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Empower Research Inc
Pregnancy Prevention
An Open-label, Randomized, 2-Period, Crossover, Pharmacokinetics Study
An Open-label, Randomized, 2-Period, Crossover Study to Assess the Comparative Pharmacokinetics of LSP-5415 and NuvaRing® in Healthy Adult Females
- Trial name
- NCT05360576
- Testing
- LSP-5415 (etonogestrel/ethinyl estradiol vaginal ring), NuvaRing Vaginal Ring
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lupin Research Inc
Parenting, Family Relations
Impact Evaluation of MotherWise Program
Mathematica was awarded a contract by ACF to conduct the evaluation of selected grantees offering Healthy Marriage and Relationship Education Programs.This particular evaluation will focus on the University of Denver's MotherWise…
- Conditions
- Parenting, Family Relations, Marriage, Mother-Child Relations
- Trial name
- NCT02792309
- Testing
- MotherWise Program
- Where
- United States
- Volunteers
- 953 people
- Sponsor
- Mathematica Policy Research, Inc.