Clinical trials: sponsored by Rush University Medical Center
HIV-1 Infections
Trial of TDF/FTC + Raltegravir Versus TDF/FTC + Efavirenz in HIV-1-Infected Women
Raltegravir not only has a unique mechanism of action, but may also have other unique effects on suppression of viral replication, viral reservoir, and immune reconstitution in blood and other important compartments.
- Trial name
- ICE-002 (NCT00984152)
- Testing
- TDF/FTC Once-Daily + Raltegravir 400 mg Orally Twice-Daily, TDF/FTC + Efavirenz (Atripla) Once-Daily
- Where
- 5 sites in United States
- Sponsor
- Rush University Medical Center
Alzheimer's Disease
Telephone Resources and Assistance for Caregivers (TRAC)
The purpose of this randomized clinical trial is to test a 12-month multi-component health promotion intervention with home-based family caregivers of persons with Alzheimer's Disease and other related dementias.
- Trial name
- TRAC (NCT00721383)
- Testing
- Enhancing Physical Activity Intervention, CSBI
- Where
- 2 sites in United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson's Disease
Evaluation of a Biomarker Related to the GI Tract for the Diagnosis of Parkinson's Disease
The cause of Parkinson's disease (PD) is currently unknown. Both environmental and genetic factors have been found to contribute to PD pathogenesis.
- Trial name
- NCT01904240
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Myelodysplastic Syndrome
Phase 2, Open-Label, Multi-Dose Study of Panhematin in Patients With MDS
This is a Phase II, open-label clinical trial examining the role of Panhematin® in patients with MDS. The objective of this study is to evaluate the safety and efficacy of Panhematin® (hematin for injection) in the treatment of…
- Trial name
- NCT00467610
- Testing
- Panhematin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis, Hip Osteoarthritis
Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties
Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time.
- Trial name
- NCT00834483
- Testing
- Knotless suture for wound closure, Layered traditional wound closure (monocryl)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Atherosclerosis, Cardiovascular Diseases
Prevalence & Progression of Subclinical Atherosclerosis
To evaluate subclinical atherosclerotic disease in menopausal women.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Carotid Artery Diseases
- Trial name
- NCT00006503
- Sponsor
- Rush University Medical Center
Asthma
Using Mobile Phones to Improve Adherence to Inhaled Steroids
This study has two main goals. The first goal is to test whether a mobile phone intervention can increase adherence to daily inhaled steroid medications in African American adolescents prescribed this type of medication by…
- Trial name
- ADEPT4 (NCT01710059)
- Testing
- Asthma Supervision, Mobile Phone, Inhaled Corticosteroid Mobile Phone Application
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases
Women's Walking Program
African American (AA) women have the lowest physical activity (PA) levels, which contributes to substantial disparities in cardiovascular health and depressive symptoms.
- Trial name
- WWP3 (NCT01700894)
- Testing
- Walking Program + Motivational Interviewing Calls, Walking Program + Automated Calls, Walking Program
- Where
- 7 sites in United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Dyslipidemia, HIV Infections
Preliminary Study of Safety and Efficacy of Policosanol
Lay Language Summary: High cholesterol levels are common in persons with HIV infection. However, conventional cholesterol-lowering medications may have harmful side effects when given to HIV-infected persons.
- Trial name
- NCT00312923
- Testing
- Policosanol
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Rush University Medical Center
Patient Admission, Patient Discharge
Combined Social Worker and Pharmacist Transitional Care Program
In an effort to improve care coordination and reduce hospital readmissions, Rush University Medical Center developed the Combined Social Worker and Pharmacist Program, which targets both the psychosocial and clinical risk factors…
- Trial name
- NCT01503554
- Testing
- Combined Social Worker and Pharmacist Program, No Intervention: Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson's Disease, Multiple System Atrophy
Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease
The gut may be a portal of entry for agents that cause or contribute to the causes of Parkinson's disease (PD). The investigators are studying changes in the normal population of gut flora and in intestinal permeability and their…
- Trial name
- NCT01155492
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Insomnia
Mindfulness-Based Approaches to Insomnia
The overall goal of this project is to evaluate the evidence for the efficacy of two mindfulness-based interventions, mindfulness-based therapy for insomnia (MBT-I) and mindfulness-based stress reduction (MBSR), for reducing…
- Trial name
- NCT00768781
- Testing
- Mindfulness-Based Stress Reduction, Mindfulness-Based Therapy for Insomnia, Wait-List + Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Rush University Medical Center
Subjective Memory Loss in Older Persons
Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints
The purpose of this six-month research study is to determine if Cerefolin NAC reduces levels of substances in the blood that may be associated with thinking ability and the health of brain cells in subjects with memory concerns…
- Trial name
- NCT00597376
- Testing
- Cerefolin NAC (a medical food)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Rush University Medical Center
Parenting
Engaging Low-Income Families in Prevention Programs
The purposes of this study are to (1) study the cost-effectiveness of childcare discounts on increasing parent participation rates in a preventive parent training program called the Chicago Parent Program and (2) evaluate the…
- Trial name
- NCT01405404
- Testing
- Parent Training and childcare discount, Parent Training
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson's Disease, Dysarthria
Improve Speech Using an In-the-ear Device in Parkinson's Disease
This project will systematically examine the therapeutic effect of altered auditory feedback provided by the in-the-ear device on the speech impairments in patients with Parkinson's disease.
- Trial name
- MJFFSpeech (NCT00488657)
- Testing
- SpeechEasy Model ITC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
HIV Infection, Hepatitis C Infection
Study on Immunopathogenesis in HIV and Hepatitis C Coinfection
Liver-related death is the leading cause of mortality in HIV-infected individuals with CD4+ cell counts over 200, and hepatitis C virus (HCV) infection is the greatest risk for liver-related mortality in HIV-positive patients.
- Conditions
- HIV Infection, Hepatitis C Infection, Fibrosis, Inflammation
- Trial name
- NCT01296529
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Rush University Medical Center
Parkinson's Disease
Use of Zolpidem in Parkinson's Disease
Levodopa treatment is associated with long-term complications. Dopamine deficiency is associated with abnormal activity in certain parts of the brain.
- Trial name
- NCT01351168
- Testing
- Levodopa, Zolpidem first dose, Zolpidem second dose
- Where
- United States
- Sponsor
- Rush University Medical Center
Allergic Conjunctivitis to Tree Pollen or Grass Pollen
Study of the Effect of Fluticasone Furoate Nasal Spray on Spring Allergy Eye Symptoms
Rationale and objectives: Fluticasone furoate nasal spray (Veramyst) has been shown to improve ocular symptoms when used for the treatment of seasonal allergic rhinitis during the ragweed pollen season.
- Trial name
- NCT00891436
- Testing
- Fluticasone furoate nasal spray
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Asthma
Coping Peer Intervention for Adherence
Inner-city African American and Hispanic adolescents suffer from disproportionately high rates of emergency room visits and hospitalizations for acute exacerbations of asthma.
- Trial name
- NCT01169883
- Testing
- Coping Peer Support, Doctor Asthma Messages, Coping Peer Asthma Messages
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Rush University Medical Center
Infection, Arthroplasty
Effect of Prophylactic Antibiotics on Intra-Operative Culture Results
Subjects will be consented and then determined randomly whether they will receive antibiotics prior to their surgery or during their surgery.
- Trial name
- NCT01174212
- Testing
- Prophylactic Antibiotics, Control Antibiotics
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Rush University Medical Center