Clinical trials: sponsored by Rush University Medical Center
Obesity
PRImary Care Strategies for Weight Management (PRISM) Study
The goal of this clinical trial pilot is to determine the feasibility of an intervention to enhance weight management in patients who have stopped taking anti-obesity/weight management medications in primary care.
- Trial name
- PRISM (NCT07288294)
- Testing
- PRISM Program
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Rush University Medical Center
Total Knee Arthroplasty
Medrol Dosepak for Outpatient Total Knee Arthroplasty
The purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA).
- Trial name
- NCT05097976
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Autism Spectrum Disorder
Improving the Part C Early Intervention Service Delivery System for Children With ASD
Despite strong consensus that early, specialized intervention for children with autism spectrum disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05114538
- Testing
- Reciprocal Imitation Training
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Rush University Medical Center
Pain Management, Abortion
Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure.
- Conditions
- Pain Management, Abortion, Second Trimester Abortion, Dilation and Evacuation
- Trial name
- PCB-KinD (NCT07487246)
- Testing
- Ketorolac, oral ibuprofen, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush University Medical Center
Chronic Pain, Neck Pain
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Chronic musculoskeletal pain (CP) is a major public health concern. Psychosocial treatments have been shown to be efficacious when compared to largely inert control conditions, but they are characterized by modest effects on…
- Conditions
- Chronic Pain, Neck Pain, Back Pain
- Trial name
- NCT06044649
- Testing
- Cognitive Behavioral Therapy, Acceptance and Commitment Therapy, Emotional Awareness and Expression Therapy
- Where
- 2 sites in United States
- Volunteers
- 408 people
- Sponsor
- Rush University Medical Center
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA)
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI).
- Conditions
- Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
- Trial name
- iBrainTechRCT (NCT07020312)
- Testing
- Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (ACL) rupture of the knee.
- Trial name
- NCT07142369
- Testing
- Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Rush University Medical Center
Cardiometabolic Health Indicators
Behavioral Economic Attributes of Recreation
Risk for developing and dying from heart disease, type 2 diabetes, stroke, and other cardiometabolic conditions is strongly influenced by behavioral risk factors, including poor diet, physical inactivity, and tobacco and alcohol…
- Trial name
- BEAR (NCT07282418)
- Testing
- Recreation Enhancement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Biologic Augmentation With Mesenchymal Stem Cells in Patients Undergoing Anterior Cruciate Ligament Reconstruction
This study will evaluate the efficacy of biologic augmentation of ACL reconstruction with bone marrow derived mesenchymal stem cells as measured by magnetic resonance imaging to detect graft healing and integration.
- Trial name
- BMAC (NCT04650568)
- Testing
- Autologous Bone Marrow Derived Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Hypertension
Church-based Intervention to Improve Blood Pressure in African Americans
This is a 12-month behavioral cluster-randomized trial testing a church-based intervention to reduce blood pressure in African Americans with uncontrolled blood pressure.
- Trial name
- NCT05220332
- Testing
- Heart to Heart, Money Smart
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Rush University Medical Center
Food Insecurity, Diabetes in Adults
RUSH Food is Medicine Veggie Rx - GusNIP Produce Prescription
The goal of this clinical trial is to assess nutrition incentives and produce vouchers to measure the impacts of food insecurity-related chronic health conditions in adults with hypertension and/or diabetes.
- Conditions
- Food Insecurity, Diabetes in Adults, Hypertension (HTN)
- Trial name
- NCT07376044
- Testing
- Food is Medicine
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
Alcohol Use Disorder, Human Immunodeficiency Virus
Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection
Alcohol use disorder (AUD) has been associated with high prevalence of inflammation-associated co-morbidities in people living with HIV even those receiving effective antiretroviral therapy (ART).
- Trial name
- NCT06139224
- Testing
- 4 week prebiotic consumption
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
PTSD
Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD
The purpose of this study is to understand if we can improve the treatment for posttraumatic stress disorder (PTSD). We are looking into whether the combination of Stellate Ganglion Block (SGB) treatment and Cognitive Processing…
- Trial name
- NCT06570213
- Testing
- Cognitive Processing Therapy, Stellate Ganglion Block
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis
ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
The aim of this study is to conduct a comparative evaluation of the ROAM OA Single Upright Brace and the Ossur Unloader One Knee Brace in subjects with medial compartment osteoarthritis.
- Trial name
- NCT07224958
- Testing
- ROAM OA Single Upright Knee Brace, Ossur Unloader One Knee Brace or Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
Dislocation, Hip
Dual Mobility Acetabular Cups in Revision TJA
The aim of this study is to the compare clinical outcomes of patients undergoing a revision total hip arthroplasty (THA) with the use of a dual mobility bearing versus a single bearing design with the use of a large femoral head…
- Trial name
- NCT04090359
- Testing
- Dual Mobility Implant, Conventional, single-bearing implant
- Where
- 2 sites in United States
- Volunteers
- 322 people
- Sponsor
- Rush University Medical Center
Knee Arthropathy, Allergic Reaction
Nickel Sensitivity
The purpose of this study is to compare clinical outcomes of patients with self reported nickel sensitivity undergoing primary total knee arthroplasty (TKA) with conventional, standard-of-care vs nickel-free implants.
- Trial name
- NCT04058743
- Testing
- TKA with nickel free components, TKA with standard cobalt chromium components
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rush University Medical Center
Violence in Adolescence, Substance Use
BrotherlyACT: A Tech-Enhanced Violence and Substance Use Intervention for Black Boys and Young Men
This study will adapt and test a culturally tailored, multi-component, and trauma-focused digital intervention to reduce the risk and effects of youth violence and substance use and bridge service access gaps for young Black…
- Conditions
- Violence in Adolescence, Substance Use, Avoidance of Healthcare
- Trial name
- BrotherlyACT (NCT06359990)
- Testing
- BrotherlyACT, BrotherlyACT Waitlist Control Group (WCG)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Post Traumatic Stress Disorder PTSD
Nurse-Led PTSD Treatment in Primary Care
Purpose of the Study Post-traumatic stress disorder (PTSD) is a common and serious condition, but many people cannot get the help they need because there are not enough mental health specialists (like psychologists or…
- Trial name
- NCT07430657
- Testing
- NurseNET, Referral to PTSD Treatment
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Hypertension
Mobilizing Community Hypertension Access Pilot
The Live Healthy Chicago (LHC) Community Pilot is a prospective, community-based study evaluating the feasibility, effectiveness, and economic impact of a pharmacist-led hypertension management program delivered in trusted…
- Trial name
- NCT07547345
- Testing
- Community-Based Multidisciplinary Hypertension Management Program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Osteoarthritis Post-meniscectomy
Autologous Bone Marrow Aspirate Concentrate in Patients Undergoing Meniscectomy
The proposed research study aims to evaluate the effects of autologous bone marrow aspirate concentrate (BMAC) on the development and progression of osteoarthritis (OA) in patients undergoing meniscectomy.
- Trial name
- NCT02582489
- Testing
- Bone Marrow Aspirate Concentrate, Standard Meniscectomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center