Clinical trials: sponsored by Rush University Medical Center
Shoulder Pain
Patient Outcomes Collection: How Can we do Better?
Patient reported outcomes (PROs) are widely used by clinical providers as important tools to help inform their clinical and research practice, and to improve quality of care for patients.
- Trial name
- NCT03653455
- Testing
- Email reminders, Pre- and Post-operative discussion, Incentive
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
Neurologic Deficits
NeuroVision vs Standard Neuromonitoring
The purpose of this study is to perform a prospective, randomized, controlled clinical trial to assess the utility of IONM in patients undergoing primary, single or multilevel lateral spinal procedures.
- Trial name
- NCT04639297
- Testing
- NeuroVision® IONM, Hospital Based IONM
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Lewy Body Dementia, Parkinson Disease Dementia
PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia
Lewy Body Dementia (LBD) is the second most common form of degenerative dementia, affecting at least 2.4 million US adults, and the overwhelming majority of persons living with LBD (PLBD) are cared for by family caregivers.
- Conditions
- Lewy Body Dementia, Parkinson Disease Dementia, Dementia With Lewy Bodies, Lewy Body Disease
- Trial name
- NCT06389032
- Testing
- Peer Mentor Support and Caregiver Education, Caregiver Education
- Where
- United States
- Volunteers
- 622 people
- Sponsor
- Rush University Medical Center
Depression
Activity and Recreation in Communities for Health
This project tests whether a health outreach intervention that promotes engagement in rewarding, community-based recreational and social activities can produce greater improvements in depressive symptoms, adiposity, and physical…
- Trial name
- ARCH (NCT06093282)
- Testing
- ARCH, Traditional Health Outreach
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Rush University Medical Center
Low Back Pain
Erector Spinae Plane Block for Acute Back Pain in the Emergency Department
The goal of this clinical trial is to learn if an erector spinae plane block (ESPB; a type of nerve block) works to reduce pain in adults presenting to the emergency department with low back pain.
- Trial name
- NCT06745453
- Testing
- Erector Spinae Plane Block
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Rush University Medical Center
Obesity
Predictors of Behavioral Obesity Treatment Outcomes
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown.
- Trial name
- REBOOT (NCT05326477)
- Testing
- Behavioral weight loss treatment
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cardiac Arrest (CA)
PRECISION-CPR: PRecision-Controlled Ventilation in CPR
Cardiac arrest is a life-threatening emergency that requires immediate treatment with cardiopulmonary resuscitation (CPR). While chest compressions circulate blood, manual ventilation provides oxygen to the patient.
- Trial name
- NCT07088120
- Testing
- Precision-Controlled Ventilation with Real-Time Feedback, Standard Manual Ventilation During CPR
- Where
- 2 sites in United States, Mexico
- Volunteers
- 852 people
- Sponsor
- Rush University Medical Center
Pain
The Use of a Digital Application for Reporting Pain and Pain Management in Home Hospice
Poor adherence to pain management and high pain intensity associated with serious, advanced illness is a major public health concern.
- Trial name
- ePainSupport (NCT04869085)
- Testing
- e-PainSupport
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Breast Cancer, Breast Cancer Triple Negative
A Study to Evaluate the Intratumoral Influenza Vaccine Administration in Patients With Breast Cancer
This Phase 1 study will assess the safety and efficacy (usefulness) of administering 2 doses of seasonal flu vaccine directly into breast cancer tissue (primary tumor), and will study the tumor and whole body response to the…
- Trial name
- NCT06229392
- Testing
- Fluzone Quadrivalent
- Where
- United States
- Sponsor
- Rush University Medical Center
Prostate Cancer
MRI Guided SBRT for Localized Prostate Cancer
This study utilizes advanced imaging techniques (mpMRI prostate scan) to select and stratify patients for two different radiotherapy regimens based on the presence/absence of identifiable intraprostatic lesions.
- Trial name
- NCT03778112
- Testing
- SBRT to whole prostate, IMRT followed by mpMRI guided SBRT boost with SIB to intraprostatic lesions
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Rush University Medical Center
Adolescent Obesity, Diabetes Mellitus
Black Girls Move Physical Activity and Improving Dietary Intake Among Black Adolescent Daughters
Black Girls Move is a school-linked daughter/mother physical activity and dietary behavior program, with 9th and 10th grade students.
- Trial name
- NCT05433415
- Testing
- Black Girls Move
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Ovarian Cancer, Breast Cancer
A Study of Serum Folate Levels in Patients Treated With Olaparib
This is a study investigating folate deficiency (lack of folic acid in the blood) in patients who take the drug olaparib to treat their advanced ovarian or breast cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Folic Acid Deficiency
- Trial name
- NCT04024254
- Testing
- Folic Acid Tablet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rush University Medical Center
PTSD
Exploring Mechanisms of Massed Cognitive Processing Therapy
The overall goal of this randomized controlled trial with partial crossover is to compare the effectiveness of 1-week virtual massed Cognitive Processing Therapy (CPT) to 5-day virtual relaxation training (RT) with regard to…
- Trial name
- NCT05265039
- Testing
- Cognitive Processing Therapy, Relaxation Training
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
PTSD
TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD
The goal of this study is to determine whether complementing regular intensive PTSD treatment with intermittent theta burst stimulation (iTBS) applied to the right dorsolateral prefrontal cortex (DLPFC) can improve treatment…
- Trial name
- NCT06271733
- Testing
- TMS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Rush University Medical Center
Decision Making
Clinical Decision-Making During FEES: The Impact of Residue Amount and Location
In this study, the investigator aims to identify the threshold of food residue visualized in the throat during a FEES (fiberoptic endoscopic evaluation of swallowing) that speech-language pathologists allow before restricting a…
- Trial name
- IRAL (NCT07278076)
- Testing
- education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pumping, Breast, Milk, Human
Reducing Disparity in Receipt of Mother's Own Milk in Very Low Birth Weight Infants
In the US, the burden of very low birth weight (VLBW; <1500 g) birth is borne disproportionately by black (non-Hispanic black/African American) mothers who are 2.2-2.6 times more likely than nonblack mothers to deliver VLBW…
- Conditions
- Pumping, Breast, Milk, Human, Infant, Very Low Birth Weight, Preterm Birth
- Trial name
- ReDiMOM (NCT04540575)
- Testing
- NICU Acquires MOM, Mother Provides MOM
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- Rush University Medical Center
Airway Clearance Impairment
Outcome Comparisons of Vibratory Airway Clearance Devices
This pilot study aims to compare the ability of a higher oscillatory index device versus a lower oscillatory index device on airway secretion clearance and other clinically significant outcomes.
- Trial name
- NCT05873504
- Testing
- High Oscillatory Index Device, Low Oscillatory Index Device
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Rush University Medical Center
Choledocholithiasis, Pancreatic Duct Stone
Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones
The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. It will also learn about the safety of the low-wattage holmium laser.
- Trial name
- NCT07418112
- Testing
- Laser lithotripsy with low-wattage holmium laser, Electrohydraulic lithotripsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Arthritis Shoulder
Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)
The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis.
- Trial name
- GHOA (NCT04949087)
- Testing
- Glenohumeral Injection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Accuracy of Pulse Oximetry Across Skin Pigmentation Levels
The Impact of Skin Tone on Pulse Oximeter Accuracy
Pulse oximeters are widely used in hospitals to estimate blood oxygen levels using a sensor placed on the skin. Recent studies suggest that pulse oximeter readings may be less accurate in individuals with darker skin tones, which…
- Trial name
- NCT07415187
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- Rush University Medical Center