Clinical trials: sponsored by Rush University Medical Center
Parkinson Disease
Kick Out Parkinson's Disease- Karate Intervention
The benefits of exercise for general health and wellbeing in older adults are well-established. Balance exercises such as tai chi and yoga, along with resistance training, can improve or maintain physical function in older adults…
- Trial name
- NCT03555695
- Testing
- Karate Classes, Pre-Intervention Focus Group, Post-Intervention Focus Group
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Rush University Medical Center
Chronic Low-back Pain, CRPS
Comparison of Continuous and Burst High Frequency Spinal Cord Stimulation Paradigms
Spinal cord stimulation (SCS) delivered at 10kHz frequency (HF10 Therapy) has demonstrated superiority to traditional SCS for leg and back pain.
- Conditions
- Chronic Low-back Pain, CRPS, Peripheral Neuropathy
- Trial name
- NCT04709757
- Testing
- Intermittent Dosing HF10 30/90, Intermittent Dosing HF10 30/360
- Sponsor
- Rush University Medical Center
After Visit Instructions, Patient Education
Impact of After Visit Instructions on Patient Comprehension
This prospective study aims to analyze the influence of standardized after visit instructions (AVI) and teach back (TB) method on patients' understanding of health information.
- Conditions
- After Visit Instructions, Patient Education, Teach-Back Communication, Patient Comprehension
- Trial name
- NCT06021730
- Testing
- Standardized After Visit Instructions Only, Standardized After Visit Instructions & Teach Back
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Patient Admission, Patient Discharge
Enhanced Discharge Planning Program -- Prospective
The Enhanced Discharge Planning Program (EDPP) is an intervention designed to help older adults safely transition to the community after discharge.
- Trial name
- EDPP (NCT01378234)
- Testing
- Enhanced Discharge Planning Program transitional care
- Where
- United States
- Volunteers
- 740 people
- Sponsor
- Rush University Medical Center
Communication, Satisfaction, Patient
Written Communication in the Intensive Care Unit
The goal of this study is to compare the experience of intensive care unit (ICU) families and care providers before and after the implementation of an approach whereby clinicians initiate written communication with families The…
- Conditions
- Communication, Satisfaction, Patient, Burnout
- Trial name
- WRITE (NCT05636371)
- Testing
- Written Communication
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Rush University Medical Center
Hypoxemic Respiratory Failure
Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia
In this study, patients who are ready for extubation and indicated for high-flow nasal cannula therapy after extubation will be enrolled, the investigators would measure the patient peak tidal inspiratory flow (PTIF) pre and post…
- Trial name
- NCT04971148
- Testing
- HFNC flow set at patient peak tidal inspiratory flow, HFNC flow set at 1.33 times of patient peak tidal inspiratory flow, HFNC flow set at 1.67 times of patient peak tidal inspiratory flow
- Where
- 2 sites in United States, Spain
- Volunteers
- 5 people
- Sponsor
- Rush University Medical Center
Anterior Cruciate Ligament Injuries, ACL
Blood Flow Restriction Following ACLR
The purpose of this study is to evaluate the the ability of BFR to reduce muscle loss and improve strength after ACL reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, ACL, Physical Therapy
- Trial name
- NCT04086030
- Testing
- Blood Flow Restriction Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Postoperative Urinary Retention, Total Hip Arthroplasty
RCT Foley Catheter Study for Elective TJA
Urinary retention is a known complication following surgical procedures, with a theoretical increased risk in patients receiving neuraxial anesthesia due to a decreased ability to sense bladder distension.
- Conditions
- Postoperative Urinary Retention, Total Hip Arthroplasty, Total Knee Arthroplasty
- Trial name
- NCT05428020
- Testing
- Indwelling foley catheter, No foley catheter
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Colorectal Cancer
Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep
This study will be comparing patient satisfaction, efficacy comparing miralax with gatorade versus Movi Prep for outpatient colonoscopy.
- Trial name
- NCT01695863
- Testing
- comparing 2 drugs on their effect on the bowel preparation for colonoscopy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Postoperative Pain
Comparing Opioid Prescription Patterns in Total Joint Arthroplasty Patients
The United States constitutes <5% of the world's population but over 80% of the opioid supply and 99% of the hydrocodone supply.
- Trial name
- NCT03236155
- Testing
- opioid pain pills
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Parkinson Disease
A Prospective Longitudinal Assessment of PD Functional Impairment and Disability Via Mobile Health Technology
The purpose of this study is to compare data from a battery of novel mobile health technologies to standard-of-care validated patient questionnaires and clinician rating scales in Parkinson's disease patients.
- Trial name
- NCT05153356
- Testing
- Personal Kinetigraph, Kinesia 360
- Sponsor
- Rush University Medical Center
Low Back Pain
Workplace Based Rehabilitation for Low Back Disorders
The purpose of this study is to examine the effect of back supports plus education upon recovery from a work-related low back disorder.
- Trial name
- NCT00316342
- Testing
- Back supports
- Volunteers
- 433 people
- Sponsor
- Rush University Medical Center
CO2 Clearance, Mask Comfort
Noninvasive Ventilation Masks Carbon Dioxide Clearance in Normal Volunteers
This study will be a randomized crossover trial that will be conducted at Rush University. The study will be conducted with 20 healthy volunteers who will be placed on ICU ventilator operating in the NIPPV mode.
- Conditions
- CO2 Clearance, Mask Comfort, Rebreathing Exhaled Gas
- Trial name
- NCT03882723
- Testing
- Evaluated 4 masks used for NIV with mechanical ventilators
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Inflammatory Bowel Diseases
Chronotherapy in Inflammatory Bowel Disease
This study aims to determine if there is any difference in the efficacy of Inflammatory Bowel Disease (IBD) medication and disease outcomes when taken in the morning or in the evening.
- Trial name
- NCT04304950
- Testing
- Evening Group, Morning Group
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Rush University Medical Center
Posttraumatic Stress Disorder, Depression
Examining Changes in Microbiota Over the Course of PTSD Treatment
The overall goals of this project are to evaluate the use of 5-day intensively-delivered Cognitive Processing Therapy to treat PTSD and to determine the associations between the microbiome, salivary cytokines, and the presence of…
- Trial name
- NCT04109196
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rush University Medical Center
Critical Illness, Circadian Dysregulation
Effect of Sleep on the Recovery of Patients Admitted to the ICU
The investigators plan to create several sleep/circadian rhythm friendly rooms within the medical intensive care unit to determine if decreasing sleep fragmentation effects recovery in patients hospitalized in the ICU.
- Conditions
- Critical Illness, Circadian Dysregulation, Delirium
- Trial name
- NCT04111900
- Testing
- Sleep/Circadian Friendly
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Rush University Medical Center
Cardiovascular Diseases, Menopause
Longitudinal Study of the Menopause and Fat Patterning
To study the natural history of the accumulation of intra-abdominal fat as women progress through the menopause.
- Conditions
- Cardiovascular Diseases, Menopause, Heart Diseases
- Trial name
- NCT00035659
- Volunteers
- 868 people
- Sponsor
- Rush University Medical Center
Major Depressive Disorder
Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy
In this Phase 4 trial we will study the safety, tolerability and efficacy of mixed salts amphetamine (MSA), trade name Adderall, augmentation of antidepressant therapy for Major Depressive Disorder (MDD) in depressed outpatient…
- Trial name
- NCT02058693
- Testing
- mixed salts amphetamine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Rush University Medical Center
Parkinson Disease
Targeting Diet-Microbiome Interactions in the Pathogenesis of Parkinson's Disease
The purpose of this study is to evaluate the microbiome of medicated and non-medicated subjects diagnosed with Parkinson's disease. Where available, in comparison to the microbiome of a healthy spouse or 1st degree relative.
- Trial name
- NCT03705520
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Rush University Medical Center
Constipation
Starch-entrapped Microspheres [Nutrabiotix Fiber] for Gut Health
The investigators hypothesize that daily oral intake of starch-entrapped alginate microspheres (called Nutrabiotix fiber) is well tolerated, exhibits no or minimal "typical" side effects of fiber (e.g.
- Trial name
- NTX (NCT01210625)
- Testing
- Nutrabiotix, Psyllium
- Where
- United States
- Sponsor
- Rush University Medical Center