Clinical trials: sponsored by Samsung Medical Center
Early Mobility, Critically Ill
Early Mobilization in Ventilated SEpsis & Acute Respiratory Failure Study
Early mobilization in Ventilated sEpsis \& acute Respiratory failure Study: EVER Study
- Trial name
- EVER (NCT04582760)
- Testing
- early mobilization
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy with Concurrent Chemotherapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by concurrent chemotherapy with hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239613
- Testing
- POHIM-CCRT
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16 fractions, once a day) after…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239626
- Testing
- POHIM-RT
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Cancer Survivorship, Breast Cancer
Development and Validation of a Personalized Digital Healthcare Model for Managing Side Effects in Breast Cancer Survivors
The ultimate goal of this research and development is to develop personalized digital healthcare technologies and self-management strategies based on self-assessment results and evidence, for breast cancer survivors who require…
- Conditions
- Breast Cancer Survivorship, Breast Cancer, Digital Health
- Trial name
- NCT06729684
- Testing
- digital health (application and smartwatch)
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Samsung Medical Center
Haploidentical Hematopoietic Stem Cell Transplantation
Haploidentical Hematopoietic Stem Cell Transplantation With Early ATG and Low Dose Post-transplant Cyclophosphamide
Aim of this study is to investigate the effect of early administration of anti-thymocyte globulin and post-transplant low-dose cyclophosphamide in heploidentical hematopoietic stem cell transplantation.
- Trial name
- NCT06041893
- Testing
- ATG-LDPTCy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Metastatic Non-Small Cell Lung Carcinoma
Pembrolizumab for Metastatic NSCLC Patients Expressing PD-L1 Who Have Their Own PDX
This is a single center, open-label, single arm study in patients with metastatic non-small cell lung cancer (NSCLC) expressing PD-L1 after failure of platinum-based combination chemotherapy.
- Trial name
- NCT03134456
- Testing
- Pembrolizumab Injection
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Bladder Cancer
Hypofractionated IMRT With Concurrent Chemotherapy in Muscle-invasive Bladder Cancer (HIRACUM)
The purpose of this study is to investigate the side effects, quality of life, and treatment effects of concurrent chemo-hypofractionated intensity-modulated radiation therapy in bladder cancer.
- Trial name
- HIRACOM (NCT05453682)
- Testing
- hypo-IMRT
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Samsung Medical Center
Neoplasm
The Samsung Medical Center Comprehensive Cancer Center Registry from 2008 to 2023
This is a retrospective cohort study using the Samsung Medical Center Cancer Registry, including cancer patients between 2008 and 2022. To monitor trends in patient demographics, treatment patterns, and outcomes.
- Trial name
- SCCCR08-23 (NCT06703957)
- Where
- South Korea
- Volunteers
- 301,055 people
- Sponsor
- Samsung Medical Center
Cohort Studies, ICU Acquired Weakness (ICUAW)
Data Analysis and Physical Function Evaluation Index Development for Early Diagnosis and Monitoring of ICU-acquired Weakness
Data Analysis and Physical Function Evaluation Index Development for Early Diagnosis and Monitoring of ICU-acquired weakness
- Conditions
- Cohort Studies, ICU Acquired Weakness (ICUAW), Critical Illness
- Trial name
- Beyond ICU (NCT06669494)
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Type 1
Individualized Automatic Target Coaching Message for Glycemic Management and Depressive Symptom
This is a single-center, randomized, prospective, feasibility and acceptability trial in patients with type 1 diabetes. For six weeks, the intervention group will receive weekly personalized coaching messages for glycemic…
- Trial name
- NCT06525454
- Testing
- Personalized coaching messages for blood glucose and emotions
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Samsung Medical Center
Diabetes Mellitus, Type 1, Continuous Glucose Measurement
Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a single-center, randomized, prospective, confirmatory study of efficacy of individualized automatic coaching message for glycemic management and depressive symptom in patients with type 1 diabetes.
- Trial name
- NCT06684678
- Testing
- individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Samsung Medical Center
Cardiogenic Shock, Acute Myocardial Infarction
Revascularization Strategy of Multivessel Disease for Patients with Acute Myocardial Infarction Complicated by Cardiogenic Shock Undergoing Veno-arterial Extracorporeal Membrane Oxygenator
This study is a prospective, open-label, two-arm, randomized multicenter trial to identify whether immediate multi-vessel PCI would be better in clinical outcomes compared with culprit lesion-only PCI for AMI and multi-vessel…
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, Multi Vessel Coronary Artery Disease, Extracorporeal Membrane Oxygenation
- Trial name
- RESCUE-SHOCK (NCT05527717)
- Testing
- Culprit lesion only PCI, Immediate multi-vessel PCI
- Where
- South Korea
- Volunteers
- 560 people
- Sponsor
- Samsung Medical Center
Neoplasm, Breast
Cooling Cap Trial to Prevent Permanent Chemotherapy-induced Alopecia in Breast Cancer Patients
This study aims to examine whether the PSCS2 is effective in reducing chemotherapy-induced alopecia in women with breast cancer undergoing neoadjuvant or adjuvant chemotherapy.
- Trial name
- NCT04678544
- Testing
- Scalp cooling system 2
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
Genetic and Histopathologic Characteristics of Interstitial Cystitis
- Trial name
- NCT03523559
- Testing
- bladder tissue of Interstitial Cystitis and normal bladder tissue
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
ST Elevation Myocardial Infarction, Non-ST Elevation Myocardial Infarction
IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MI
The aim of the study is to compare clinical outcomes between intravascular ultrasound (IVUS)-guided treatment decision versus fractional flow reserve (FFR)-guided treatment decision for non-infarct related artery stenosis in…
- Trial name
- FRAME-AMI2 (NCT05812963)
- Testing
- IVUS-guided PCI group, FFR-guided PCI group
- Where
- 2 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Stroke, Repetitive Transcranial Magnetic Stimulation
Effect of Cerebral and Cerebellar rTMS in Stroke Patient
This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients.
- Conditions
- Stroke, Repetitive Transcranial Magnetic Stimulation, rTMS, Motor Recovery
- Trial name
- NCT04570774
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Epilepsy
A Study on Telemedicine Applied to Actual Outpatient Clinic for Epilepsy
This is an observational study to confirm the non-inferior effectiveness on health outcomes of tele-counseling or tele-prescription, which was the first outpatient system applied to the actual medical sites in Korea during the…
- Trial name
- NCT05418257
- Testing
- (exposure) telemedicine
- Where
- South Korea
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Coronary Artery Disease, Percutaneous Coronary Intervention
Prospective Pecutaneous Coronary Intervention Registry
Coronary artery disease is the most important cause of death worldwide. Treatment option for coronary artery disease is medical treatment, percutaneous coronary intervention, or coronary artery bypass surgery.
- Trial name
- SMC-PCI (NCT05624905)
- Testing
- Percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 15,000 people
- Sponsor
- Samsung Medical Center
Pain, Chronic
Usability Evaluation of a Mindfulness-based Serious Game
The purpose of this study is to evaluate the usability of a mindfulness-based serious game developed for pediatric and adolescent patients who require pain management during their disease treatment.
- Trial name
- NCT06522425
- Testing
- mindfulness-based serious games
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Uterine Cervical Neoplasms
Comparison of Conventional and Hypofractionated IMRT in High-Risk Cervical Cancer Post-Radical Hysterectomy
Radical hysterectomy and radiation therapy are standard treatments for cervical cancer. However, there are no reported studies on the frequency of side effects and treatment outcomes when hypofractionated radiation therapy and…
- Trial name
- POHIM-P3 (NCT06509724)
- Testing
- Conventional Fractionated IMRT, Hypofractionated IMRT
- Where
- South Korea
- Volunteers
- 248 people
- Sponsor
- Samsung Medical Center