Clinical trials: sponsored by Samsung Medical Center
Acute ST-segment Elevation Myocardial Infarction
Prognostic Implication of Angiography-Derived IMR in STEMI Patients
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of STEMI patients. Previous study presented that index of microcirculatory resistance (IMR) in culprit vessel of STEMI…
- Trial name
- NCT04628377
- Testing
- Angiography-drived Index of Microcirculatory Resistance
- Volunteers
- 333 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Long-term Outcomes and Prognostic Factors in Patient Undergoing CABG or PCI
1. To evaluate the long-term clinical outcomes and prognostic factors in patients with coronary artery disease undergoing coronary artery bypass graft surgery. 2.
- Trial name
- NCT03870815
- Testing
- CABG, PCI
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC
This randomized, Phase III, multicenter, open-label study designed to evaluate the efficacy of Atezolizumab in combination with carboplatin, paclitaxel, bevacizumab compared with treatment with pemetrexed, cisplatin in…
- Trial name
- NCT03991403
- Testing
- Atezolizumab(Tecentriq), Pemetrexed, Bevacizumab
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- Samsung Medical Center
Chronic Stroke
Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients
In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.
- Trial name
- NCT03392519
- Testing
- Chronic stroke
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Stroke
Recovery Prediction of Motor Function Using Neuroimaging Techniques in Subacute Stroke Patients
Prediction of recovery from stroke can assist in the planning of impairment-focused rehabilitation. To achieve better prediction for clinical purposes, this study investigated a new prediction model with low inter-individual…
- Trial name
- NCT03365596
- Testing
- Conventional therapy
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke
Effect of Intensive Cognitive Rehabilitation on Cognitive, Motor, and Language Functional Networks in Subacute Stroke Patient
Altered brain networks, including cognitive, motor, and language networks, are investigated by intensive cognitive rehabilitation in subacute stroke patients.
- Trial name
- NCT05254964
- Testing
- Cognitive rehabilitation
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Insulin Resistance
The Effect of Mobile Health-based Exercise on Hepatocellular Carcinoma Patients With Insulin Resistance
Exercise is predicted to have positive effect among patients with hepatocellular carcinoma (HCC). However, little attention has been paid to the role of physical activity with wearable device in the management of HCC patients in…
- Trial name
- NCT04649671
- Testing
- Mobile health
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gait
Development of Fall Prediction Model for Older Adults Based on Multi-faceted Data
This study aimed to develop a fall prediction model for older adults by measuring the multi-faceted biosignal data to classify the walking patterns and by identifying causal relationships with the variables that affect the fall.
- Trial name
- NCT04723927
- Testing
- Older adults
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Aerobic Exercises, Anaerobic Exercises
The Effect of EX1 Training in Normal Adults
In this study, when performing aerobic and anaerobic exercise with EX1 applied to normal adults between the ages of 19 and 65. The purpose of this study was to determine the effect on the muscle activity of the trunk and lower…
- Trial name
- NCT05266170
- Testing
- aerobic and anaerobic exercises
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gait Disorders in Old Age
Usability and Satisfaction Test to the Wearable Walking-assist Robot (GEMS-H) in the Community-dwelling Healthy Adults
The purpose of this study is to investigate the userbility and satisfaction of one-off functional gait training with the Gait Enhancing and Motivating System-Hip type (GEMS-H) on locomotor function in normal adults including the…
- Trial name
- NCT05106881
- Testing
- Training with Gait Enhancing and Motivating System (GEMS-H) Robot
- Where
- South Korea
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Chronic Stroke
Data Collection for Motor Function and Gait Pattern Analysis of Patients With Chronic Stroke
In chronic stroke patients, the data for motor function and gait pattern analysis was obtained.
- Trial name
- NCT03468166
- Testing
- Chronic stroke
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Stroke
The Effect of tDCS Based on Functional Brain Imaging for Subacute Stroke Patients
The purpose of this study is to investigate whether brain imaging-based hand function area tDCS stimulation is more effective than conventional stimulation or sham stimulation for improving hand motor function.
- Trial name
- NCT05142917
- Testing
- Transcranial Direct Current Stimulation, Hand motor task
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Samsung Medical Center
Aging
The Effect of Exercise With Wearable Walking Assist Robot in Various Environments
This single-blinded, randomized, controlled trial includes 60 healthy adults. The participants were randomized to four different groups.
- Trial name
- NCT04920201
- Testing
- Over-ground walking without GEMS-H, Over-ground walking with GEMS-H with resist mode, Stair ascent with GEMS-H with assist mode
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Sub-acute Stroke
Functional Recovery Changes in Subacute Stroke Patients
In subacute stroke patients, dynamic time series data of brain imaging and motor function measurement were obtained from 7 days to 6 months (total 9 times) after stroke onset
- Trial name
- NCT03428659
- Testing
- Data acquisition of functional abilities in sub-acute stroke
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Samsung Medical Center
Stroke
Differences in Brain Activity in the Application of Upper Limb Exercise Tasks Through Virtual Reality
This study aims to find out the difference in brain activity when performing upper limb exercise tasks through virtual reality-based MOTOCOG equipment for chronic stroke patients.
- Trial name
- NCT05743296
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Samsung Medical Center
Stroke
The Effect of tDCS on Motor Learning and Neural Network in Stroke Patients
This study is to investigate the effect of transcranial direct current stimulation (tDCS) simulation on motor learning to stroke patients compared to sham stimulation
- Trial name
- NCT04903457
- Testing
- Transcranial Direct Current Stimulation, Motor learning
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Application of Transcranial Direct Current Stimulation (tDCS) for Gait Function Improvement of Parkinson's Disease Patient
The purpose of this study was to investigate the effect of simultaneous application of transcranial direct current stimulation (tDCS) and treadmill gait training for gait function recovery in Parkinson's disease patients with…
- Trial name
- NCT04591236
- Testing
- Brain stimulation, Treadmill gait training
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Pancreatic Ductal Adenocarcinoma
Nab-pacliatxel Plus Gemcitabine in Korean Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Nab-paclitaxel (interchangeable with ABRAXANE and ABI-007) is a unique protein formulation of a noncrystalline, amorphous form of paclitaxel in an insoluble particle state.
- Trial name
- NCT02426281
- Testing
- nab-paclitaxel, gemcitabine
- Where
- 8 sites in South Korea
- Volunteers
- 111 people
- Sponsor
- Samsung Medical Center
Stroke
Individualized Brain Stimulation Using Transcranial Direct Current Stimulation Simulation in Stroke Patients
This study is to investigate the effect of transcranial direct current stimulation (tDCS) simulation-based individualized stimulation compared to conventional stimulation and sham stimulation.
- Trial name
- NCT04699331
- Testing
- Transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Lung Cancer Stage IV, EGFR T790M
Lazertinib 160mg in EGFR T790M NSCLC
The lazertinib is currently approved as 2nd line T790M mutation-positive NSCLC that failed from either 1st or 2nd generation EGFR TKI. The current recommended dosage is 240mg.
- Trial name
- NCT05701384
- Testing
- Lazertinib
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Samsung Medical Center