Clinical trials: sponsored by Samsung Medical Center
Tricuspid Regurgitation
SGLT2 Inhibitor for Severe Tricuspid Regurgitation
The purpose of this study to identify the efficacy of sodium glucose cotransporter 2 inhibitors add-on treatment on right ventricular remodeling and the amount of severe tricuspid regurgitation (TR) in patients with isolated…
- Trial name
- Reduction-TR (NCT05686616)
- Testing
- Dapagliflozin Propanediol Hydrate 12.3 mg
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Samsung Medical Center
Rocuronium, Body Composition
Relationship Between Effect Duration of Rocuronium and Body Composition Analysis Data.
The induction dose of rocuronium is typically decided based on the patient's body weight, but the effect duration of rocuronium is variable.
- Trial name
- NCT05515835
- Testing
- body composition analysis
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Samsung Medical Center
Remimazolam, Body Composition
Body Composition Analysis and Time to Emergence From Remimazolam
Remimazolam is a novel general anesthetic drug. The time to emergence from remimazolam-based general anesthesia is variable among patients, but little is known about the risk factors for delayed emergence.
- Trial name
- NCT05512559
- Testing
- body composition analysis
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Occupational Exposure, Occupational Problems
Relationship Between Health Risk and Occupational Exposure of ED
This study established a sub-cohort of emergency medical workers, for the development of health care and disease prevention solution, by identifying epidemiological characteristics and factors related to occupational exposure.
- Conditions
- Occupational Exposure, Occupational Problems, Occupational Burnout, Medical Emergencies
- Trial name
- NCT05651477
- Testing
- Wearable Device (Smart Watch), Edge-Box
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Lung Cancer, Lung Neoplasm
Comprehensive Care Program for Their Return to Normal Life Among Lung Cancer Survivors
The purpose of this study is to develop a comprehensive care program for their return to normal life and community among lung cancer survivors and evaluate the effectiveness of the program.
- Trial name
- NCT05078918
- Testing
- Comprehensive care program, Usual care
- Where
- South Korea
- Volunteers
- 800 people
- Sponsor
- Samsung Medical Center
Telerehabilitation, Geriatrics
The Exploratory Study of AR-based Home Rehabilitation Exercise Combined With Wearable Sensor (IMU) in the Elderly
According to the results of a systematic literature review and meta-analysis based on recent studies on exercise interventions for the elderly based on augmented reality, virtual reality, and functional games, these…
- Conditions
- Telerehabilitation, Geriatrics, Exercise
- Trial name
- NCT05598463
- Testing
- OASIS Pro
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Samsung Medical Center
Occupational Diseases, Emergency Departments
Establishing a Cohort for Occupational Disease of Emergency Medical Workers
This study aims to understand the epidemiological characteristics, related factors , and current status of occupational diseases and damage that occur in emergency medical workers (doctors and nurses).
- Trial name
- NCT05357365
- Testing
- questionnaire survey
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Samsung Medical Center
Gastric Cancer
Pilot Study of Antiviral Treatment in Combination With Low-dose Gemcitabine in EBV-associated Gastric Cancer (EBVaGC)
Epstein-Barr virus (EBV) is a double-stranded DNA human gamma herpes virus that establishes a persistent infection in over 90% of individuals.
- Trial name
- NCT05431244
- Testing
- Antiviral treatment in combination with low-dose gemcitabine
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Heart Failure With Preserved Ejection Fraction, Left Ventricular Diastolic Dysfunction
Invasive Left Heart Catheterization Registry
Retrospectively enrolled suspicious of heart failure with preserved ejection fraction (HFpEF) patients who underwent left heart catheterization with the measurement of left ventricular end-diastolic pressure.
- Trial name
- NCT04505449
- Testing
- Left heart catheterization
- Where
- South Korea
- Volunteers
- 404 people
- Sponsor
- Samsung Medical Center
Interstitial Cystitis
The Efficacy and Safety of Intravesical Hyaluronic Acid and Chondroitin Sulfate After Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients
The efficacy and safety of intravesical hyaluronic acid and chondroitin sulfate after transurethral resection of Hunner lesion in interstitial cystitis/bladder pain syndrome patients.
- Trial name
- NCT03463499
- Testing
- Hyaluronic Acid and Chondroitin Sulfate
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Automated Algorithm Detecting Physiologic Major Stenosis and Its Relationship With Post-PCI Clinical Outcomes
The presence of myocardial ischemia is the most important prognostic indicator in patients with coronary artery disease. Therefore, the purpose of percutaneous coronary intervention (PCI) is to relieve myocardial ischemia caused…
- Trial name
- Algorithm-PCI (NCT04304677)
- Testing
- Percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 486 people
- Sponsor
- Samsung Medical Center
Gastric Cancer
Postoperative Prognosis Management Service Based mHealth for Gastric Cancer Patients
Recently, the use of mobile health is increasing for the purpose of managing prognosis such as recurrence, survival and quality of life by using a wearable smart band together with a smartphone application.
- Trial name
- NCT04907591
- Testing
- mHealth App and wearable device
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Samsung Medical Center
Ischemic Heart Disease
Prognostic Perspective of Invasive Hyperemic and Non-Hyperemic Physiologic Indices Measured After Percutaneous Coronary Intervention
Coronary physiologic assessments by the pressure-derived fractional flow reserve (FFR) have become standard methods for identifying hemodynamic deprivation in coronary arterial stenosis for evidence-based percutaneous coronary…
- Trial name
- PERSPECTIVEPCI (NCT04265443)
- Testing
- Percutaneous coronary intervention
- Where
- 5 sites in South Korea
- Volunteers
- 588 people
- Sponsor
- Samsung Medical Center
Breast Cancer Lymphedema
Effect of Prophylactic Medical Compression Therapy on the Reduction of Breast Cancer-related Lymphedema in Patients With Adjuvant Docetaxel Chemotherapy: a Randomized Controlled Study
In this study, the purpose of this study is to investigate whether prophylactic medical compression therapy in breast cancer patients receiving docetaxel adjuvant chemotherapy could reduce the incidence and severity of lymphedema…
- Trial name
- NCT04787029
- Testing
- Medical compression stocking (medical device name: mediven Harmony 734 (compression class1 AG armsleeve or with wide(735))
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Cancer
Feasibility of a Modular mHealth for Tailored Rehabilitation of Breast Cancer
This study investigated the feasibility of the novel modular mobile health (mHealth) for personalized rehabilitation and explored the participants' satisfaction and app data during treatment of breast cancer.
- Trial name
- MMHTR (NCT04781712)
- Testing
- Modular mHealth for Tailored Rehabilitation
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Rectal Cancer, Rectosigmoid Cancer
A Study to Validate the Safety and Feasibility of ArtiSential in Colorectal Cancer Surgery Using Prospectively Constructed Multi-center Registry
This study is to validate the safety and feasibility of ArtiSential (Articulating laparoscopic instrument) colorectal surgery and compare it with robotic surgery for patients with rectal cancer and rectosigmoid junction cancer.
- Conditions
- Rectal Cancer, Rectosigmoid Cancer, Rectosigmoid Junction Cancer
- Trial name
- NCT05566249
- Testing
- ArtiSential
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Aging
The Impact of Multi-Touch Functional Digital Game on Intelligence and Vitality for the Community-dwelling Elderly
This single-blinded, randomized, controlled trial includes 32 elderly. The participants were randomized to intervention(Happy Table) and control(cognitive stimulation activity) groups. Each group is divided in 16 participants.
- Trial name
- NCT04873843
- Testing
- Functional digital game training group, Individual cognitive training
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Multiple Myeloma
Randomized Phase II Study in Elderly Patients With Newly Diagnosed Multiple Myeloma
To compare the efficacy and safety of bortezomib, lenalidomide and dexamethasone in elderly frail patients with newly diagnosed multiple myeloma.
- Trial name
- KMM1910 (NCT04277845)
- Testing
- Bortezomib, Lenalidomide, Dexamethasone
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Samsung Medical Center
Hypotension, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Use of Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia: A Prospective Observational Study
This observational study is to evaluate Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia.
- Trial name
- NCT03556969
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Samsung Medical Center
Multiple Myeloma
Phase II Study of Carfilzomib, Pomalidomide, and Dexamethasone for Myeloma Patients Who Had Relapsed or Progressed After Carfilzomib, Lenalidomide, and Dexamethasone
The purpose of this study is to evaluate the evaluate the efficacy and safety of administering a combination of carfilzomib, pomalidomide, and dexamethasone in patients with relapsed or advanced multiple myeloma after…
- Trial name
- KMM2002 (NCT05509374)
- Testing
- Carfilzomib 56 MG [Kyprolis], Pomalidomide, Dexamethasone
- Where
- South Korea
- Volunteers
- 33 people
- Sponsor
- Samsung Medical Center