Clinical trials: sponsored by Samsung Medical Center
Stroke
Factors Related to Functional Recovery Using Brain Imaging of Stroke Patients
In this study, brain imaging predictive factors related to motor recovery will be investigated. Lastly, the prediction model will be established.
- Trial name
- NCT03632070
- Testing
- Data acquisition of functional abilities
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Samsung Medical Center
Blastic Plasmacytoid Dendritic Cell Neoplasm
Blastic Plasmacytoid Dendritic Cell Neoplasm in Korean Population.
Retrospective study , To analyze the clinical features and treatment outcomes in Korean blastic plasmacytoid dendritic cell neoplasm.
- Trial name
- KBPDCN (NCT03974971)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Myelodysplastic Syndrome
Clinical Relevance of DNMT and HDAC Gene SNP on the Response to Decitabine Therapy for Myelodysplastic Syndrome
Recent investigations have demonstrated that DNMT gene polymorphisms can contribute to the inter-individual variants in DNMT expression.
- Trial name
- NCT04515914
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Samsung Medical Center
Infection
Effectiveness of Vancomycin Loading Therapy
The goal of tish clinical research study is to identify that loading of vancomycin can facilitate rapid attainment of target trough serum vancomycin concentration.
- Trial name
- NCT01623817
- Testing
- Vancomycin HCL
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation, Persistent, Cardiac Rehabilitation
Exercise-based Cardiac Rehabilitation After Thoracoscopic Ablation in Patients With Persisent Atrial Fibrillation
Thoracoscopic ablation is a promising treatment of persistent atrial fibrillation. However, the postoperative rehabilitation is very important to prevent early recurrence of atrial arrhythmia.
- Conditions
- Atrial Fibrillation, Persistent, Cardiac Rehabilitation, Cardiopulmonary Fitness
- Trial name
- NCT04500184
- Testing
- cardiac rehabilitation
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy, Physical Activity
Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy
This research analyzes whether hippotherapy improves the physical activity, cardiopulmonary fitness, and attention in children with cerebral palsy and whether this enhances their general health and quality of life.
- Conditions
- Cerebral Palsy, Physical Activity, Attention Disorder
- Trial name
- NCT03870893
- Testing
- hippotherapy
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation, Anticoagulants and Bleeding Disorders
Safety and Efficacy of Edoxaban in Thoracoscopic Ablation
The aim of this study is to compare the safety and efficacy of edoxaban and warfarin for prevention of stroke during a 6-month follow up after total thoracoscopic ablation.
- Trial name
- NCT04121767
- Testing
- Edoxaban, Warfarin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy Spastic Hemiplegic
Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
This study evaluates the therapeutic effects of constraint-induced movement therapy on infants and children with hemiplegic cerebral palsy.
- Trial name
- NCT03858335
- Testing
- Constraint-induced movement therapy
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Thymic Epithelial Tumors
A Study of Pembrolizumab for Patients With Thymic Epithelial Tumor
This is a Phase II single center, open-label, single arm study in patients with advanced thymic epithelial tumors after failure of cisplatin-based combination chemotherapy.
- Trial name
- NCT02607631
- Testing
- Pembrolizumab
- Volunteers
- 33 people
- Sponsor
- Samsung Medical Center
Metastatic Breast Cancer
A Phase II, Single-Arm Trial of Poziotinib as Salvage Treatment in Patients With Metastatic Breast Cancer Who Has HER2 or EGFR Mutation or Activated AR or EGFR Pathway
Metastatic breast cancer (MBC) is an incurable disease and is needed to improve effective therapeutic strategies including targeted agents.
- Trial name
- NCT02544997
- Testing
- Poziotinib
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Samsung Medical Center
Dry Eye
Clinical Outcome of Lipiflow Treatment Prior to Cataract Surgery in Dry Eye Patients
To investigate the clinical outcome of Lipiflow treatment prior to cataract surgery in patients with meibomian gland dysfunction and dry eye disease
- Trial name
- NCT04457999
- Testing
- Lipiflow Thermal pulsation
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cardiotoxicity, Breast Cancer
Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer
Comparing preventive effect of myocardial global longitudinal strain-based cardioprotective stragety (angiotensin receptor blocker prophylaxis) with left ventricular ejection fraction-based strategy in breast cancer patients…
- Conditions
- Cardiotoxicity, Breast Cancer, Prevention, Adjuvant
- Trial name
- NCT04429633
- Testing
- Candesartan
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Samsung Medical Center
Dry Eye
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery
To evaluate the clinical outcomes of the systemic re-esterified triglyceride (rTG) form of omega-3 fatty acids in patients with dry eye symptoms after cataract surgery
- Trial name
- NCT04411615
- Testing
- Omega 3
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke
Dual Site-dual Channel Non-invasive Brain Stimulation for Motor Function in Stroke Patients
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in post stroke patients.
- Trial name
- NCT03486769
- Testing
- M1 stimulation, PMC stimulation, aIPS stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Stroke
Effect of Robot Gait Training With Brain Stimulation on Gait Function in Stroke Patients
The purpose of this study was to investigate the effects of robot gait training with the noninvasive brain stimulation in stroke patients.
- Trial name
- NCT03708016
- Testing
- Robot gait training, Brain stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Stroke, Aphasia
Dual Site-dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Stroke Patients
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in post stroke patients.
- Conditions
- Stroke, Aphasia, Cognitive Impairment
- Trial name
- NCT03486782
- Testing
- IFG stimulation, DLPFC stimulation, aphasia therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Presbyopia
Clinical Outcome of Extended-depth-of-focus Intraocualr Lens (SAV) Implantation
Clinical outcome of extended-depth-of-focus intraocular lens (SAV) implantation
- Trial name
- NCT04391972
- Testing
- SAV
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Cancer Metastatic
Cohort Study of Patients With HER2-negative MBC and BRCA 1/2 Pathogenic Mutation
The purpose of this study is to investigate the prevalence germline pathogenic BRCA1/2 mutation in a large group of potential candidate of PARP inhibitors, among the unselected patients with HER2-negative unresectable locally…
- Trial name
- BRCAm (NCT04368442)
- Where
- South Korea
- Volunteers
- 583 people
- Sponsor
- Samsung Medical Center
Breast Cancer
High Risk ER+HER2- T1-2N0-1 Early Breast Cancer With Palbociclib Plus Endocrine Therapy(HIPEx)
This is a phase II, multi-center, single-arm, open-label trial to evaluate efficacy of palbociclib with endocrine therapy as adjuvant treatment in women with C-high/G-high risk ER-positive/HER2-negative T1-2N0-1 EBC(Early Breast…
- Trial name
- NCT04247633
- Testing
- Palbociclib
- Where
- South Korea
- Volunteers
- 578 people
- Sponsor
- Samsung Medical Center
Adenocarcinoma of Rectum
Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients
Statins are widely used as lipid-lowering agents to lower cardiovascular risk with a favorable safety profile. In our recent in vitro study, the addition of simvastatin to chemoradiotherapy with 5-FU showed synergistic anticancer…
- Trial name
- NCT02161822
- Testing
- simvastatin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center