Clinical trials: sponsored by Samsung Medical Center
Breast Cancer, Chronic Post-Procedural Pain
The Effects of Anesthetics on Persistent Pain Following Breast Cancer Surgery
Persistent postoperative pain occurs up to 25 to 60 % after mastectomy. This occurs at a higher frequency than the rate of invasive surgery.Therefore, many ways have been tried to study risk factors.
- Trial name
- NCT03782896
- Testing
- acute postoperative pain
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Cancer Anaemia
Intravenous Iron Injection in Cancer Patients With Anemia
Multifactorial pathogenesis is involved in anemia of cancer patients and defining the causes of anemia is not always simple. Currently, treatment options available for anemia in cancer patients include red blood cell (RBC)…
- Trial name
- NCT04187716
- Testing
- Ferinject
- Where
- South Korea
- Volunteers
- 341 people
- Sponsor
- Samsung Medical Center
Type 2 Diabetes
Digital Integrated Healthcare Platform in Patients With Type 2 Diabetes
In this three multicenter clinical trial, investigators will study the efficacy of digital integrated healthcare platform and CGMS (continuous glucose monitoring system) on diabetes management in patients with Type 2 diabetes.
- Trial name
- NCT04161170
- Testing
- Digital integrated healthcare platform
- Where
- South Korea
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Bronchopulmonary Dysplasia (BPD)
No Treatment Versus Oral Ibuprofen Treatment for Patent Ductus Arteriosus in Preterm Infants
The purpose of this study is to evaluate the efficacy and safety of no treatment compared with ibuprofen treatment for patent ductus arteriosus in preterm infants.
- Trial name
- NCT02128191
- Testing
- Oral ibuprofen, Normal saline
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Samsung Medical Center
Stomach Cancer
A Phase I Study of High Dose Simvastatin in Patients With Gastrointestinal Tract Cancer Who Failed to Standard Chemotherapy
Simvastatin 5-10mg/kg bid for 7 days and 14 days off treatment for 21 days Cohort 1: 7.5 mg/kg bid for 7 days 14 days off Cohort 2: 10 mg/kg bid for 7 days 14 days off Cohort 3: ( ) mg/kg bid for 7 days 14 days off (to be…
- Trial name
- NCT03086291
- Testing
- Simvastatin
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Advanced Gastric Cancer
Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy
This study is a single arm, single center phase II study of AZD5363 in combination with paclitaxel in patients with advanced gastric adenocarcinoma harboring PIK3CA mutation or amplification as a second line chemotherapy.
- Trial name
- NCT02451956
- Testing
- AZD5363, paclitaxel
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Colorectal Cancer
Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic.
The next generation of personalized medical treatment according to the type of personal genetic information are evolving rapidly. The genome analysis needs systematic infra and database based on personal genetic information.
- Trial name
- NCT02593591
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Advanced Gastric Adenocarcinoma
Study of AZD6094 (Volitinib) in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With MET Overexpression as a Second-line Treatment
Phase II, single-arm study of AZD6094 (Volitinib) in combination with docetaxel, in advanced gastric adenocarcinoma patients with MET overexpression as a second-line treatment.
- Trial name
- NCT02447380
- Testing
- AZD6094, Docetaxel
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Samsung Medical Center
Refractory Solid Tumors
Study to Evaluate the Safety and Efficacy of Sorafenib, in Subject With Refractory Solid Tumors
This study is a single arm, pilot study of Sorafenib in patient with BRAF mutation Refractory solid tumor and specific sensitivity to Sorafenib by Avatar scan that has progressed following standard therapy or that has not…
- Trial name
- NCT02691780
- Testing
- Sorafenib
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Gastric Cancer
Trial Comparing Capecitabine Plus Oxaliplatin (XELOX) and Capecitabine (X) as First-line Chemotherapy in Elderly Patients With Advanced Gastric Cancer
The objective of the trial is to compare Overall survival between capecitabine plus oxaliplatin (XELOX) and capecitabine (X) as first-line chemotherapy in elderly patients with advanced gastric cancer.
- Trial name
- NCT01470742
- Testing
- XELOX, XELODA
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Neuroendocrine Carcinoma, Grade 3
Phase II Study of Avelumab in Metastatic Gastronetro-pancreatic （GEP） Neuroendocrine Carcinoma （NEC, WHO Grade 3） as Second-line Treatment After Failing to Etoposide+Cisplatin: Integration of Genomic Analysis to Identify Predictive Molecular Subtypes
Phase II study of avelumab in metastatic gastronetro-pancreatic (GEP) neuroendocrine carcinoma (NEC, WHO grade 3) as second-line treatment after failing to etoposide+cisplatin: integration of genomic analysis to identify…
- Trial name
- MS100070-0177 (NCT03147404)
- Testing
- Avelumab
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Samsung Medical Center
Rupture of Anterior Cruciate Ligament
Comparison of Femoral Tunnel and Clinical Outcome Using Two Anterior Cruciate Ligament Reconstruction Techniques
1. Purpose :To compare of femoral tunnel placement, tunnel geometry and clinical outcome using two anterior cruciate ligament reconstruction techniques ; transportal technique with flexible reamer and single bundle outside in…
- Trial name
- NCT02754674
- Testing
- type of anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Samsung Medical Center
Breast Cancer
T-DM1 in HER2-positive Metastatic/Relapsed Breast Cancer
This is a retrospective, multicenter, non-interventional study for the evaluation of real-world efficacy and safety of T-DM1 in metastatic/relapsed HER2-positive breast cancer as part of the establishment of hospital medical…
- Trial name
- NCT04202328
- Where
- 60 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Focal Nodular Hyperplasia
Superb Microvascular Imaging in Focal Nodular Hyperplasia
Focal nodular hyperplasia (FNH) in liver is the second common benign hepatic tumor. It usually shows hypervascular mass on imaging studies and it is not easy to differentiate with other hypervascular malignant tumor.
- Trial name
- NCT02737865
- Testing
- Sonazoid, Superb-Microvascular imaging
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Samsung Medical Center
Hypopharyngeal Cancer
Neoadjuvant Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN)
The investigators will examine whether 2-cycles of DFP chemotherapy before definitive concurrent chemoradiation therapy (CCRT) can improve progression-free survival in locally advanced (Stage III \& IVM0) hypopharyngeal and base…
- Trial name
- NCT01312350
- Testing
- neoadjuvant docetaxel/cisplatin/fluorouracil, No treatment before definitive CCRT
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer Metastatic
Chemotherapy With Pembrolizumab Continuation After Progression to PD-1/L1 Inhibitors
After progression to previous PD-1/L1 inhibitors (pembrolizumab, nivolumab, or atezolizumab), physicians' choice chemotherapy plus pembolizumab (or placebo) will be administered (3 weeks per cycle) until disease progression or…
- Trial name
- NCT03656094
- Testing
- Pembrolizumab plus chemotherapy
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Samsung Medical Center
Esophageal Cancer
Adjuvant Durvalumab for Esophageal Cancer
Adjuvant Durvalumab vs Placebo for 1 year after complete resection of esophageal cancer following neoadjuvant CCRT.
- Trial name
- NCT02520453
- Testing
- Durvalumab
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
SCLC
Pazopanib Maintenance for SCLC
To evaluate the efficacy of pazopanib maintenance after 1st line CTx for SCLC.
- Trial name
- NCT01797874
- Testing
- Pazopanib
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Samsung Medical Center
Stroke, Gait, Hemiplegic
The Effect of a Ankle Assist Robot on Gait Function and Cardiopulmonary Metabolic Efficiency in Stroke Patients
The aim of this study was to identify the assistance effect of Ankle Assist Robot v1 developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd., Korea) by comparing 1.
- Trial name
- NCT03767205
- Testing
- Ankle Assist Robot
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Samsung Medical Center
Needle Stick Injuries
A Single-institutional Study to Assess the Time Efficiency and Working Satisfaction Using ANDY(Automatic Needle Destroyer)
Evaluate the efficiency of adopting the automated needle processing system by evaluating efficiency, usability and safety when using ANDY(Automatic Needle Destroyer).
- Trial name
- NCT04039906
- Testing
- Removal of needle with using ANDYs
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Samsung Medical Center