Clinical trials: sponsored by Samsung Medical Center
Prostatic Cancer
Autologous Dendritic Cell Therapy for Hormone-Refractory Metastatic Prostate Cancer
This is an open label, Phase I/IIa trial of immunotherapy with CreaVax-PC as treatment in men with hormone-Refractory Metastatic Prostate Cancer.
- Trial name
- NCT01171729
- Testing
- Autologous dendritic cell
- Where
- 2 sites in South Korea
- Volunteers
- 12 people
- Sponsor
- Samsung Medical Center
Bone Tumors
Navigation Surgery for Bone and Soft Tissue Tumor
Bone tumor near the articular cartilage is hard to remove sufficiently without damaging adjacent joint. The purpose of this study was to evaluate the feasibility of navigation-assisted surgery for saving joint in bone tumor…
- Trial name
- NCT01179698
- Testing
- Navigation surgery, Navigation system
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Accommodative Esotropia
Under-correction in Refractive Accommodative Esotropia
In most clinics, physicians reduce diopter of hyperopic glasses in older patients with accommodative esotropia. However, there are risks of decompensation in that practice.
- Trial name
- NCT01179711
- Testing
- Glasses prescription
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Delayed Bleeding
Comparison of Proton Pump Inhibitor and H2 Receptor Blocker on Prevention of Bleeding From Iatrogenic Ulcer After Endoscopic Submucosal Dissection for Gastric Neoplasms: A Prospective Randomized Controlled Trial
after endoscopic submucosal dissection(ESD) of early gastric cancer, conventional proton pump(PPI) inhibitors and H2 receptor antagonists have a controversial effect on preventing bleeding from artificial ulcers.
- Trial name
- NCT01179724
- Testing
- high dose proton pump inhibitor, H2RB
- Where
- South Korea
- Volunteers
- 206 people
- Sponsor
- Samsung Medical Center
Amblyopia
Thickness of Retinal Layers in Amblyopia
The purpose of this study is to examine retinal layer thickness in amblyopia.
- Trial name
- NCT01179763
- Testing
- Optical coherence tomography
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Samsung Medical Center
Prostatic Neoplasms, Quality of Life
Quality of Life in Men Undergoing Robotic Assisted Laparoscopic Radical Prostatectomy Versus Radical Retropubic Prostatectomy
This study is prospective evaluation of quality of life in men undergoing robotic assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy.
- Trial name
- NCT01173952
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Globus Pharyngeus
Prevalence of Salivary Hypofunction in Patients With Globus Pharyngeus
It is well known that 'globus sensation in throat' is caused by the chronic irritation and inflammation of oral, pharyngeal, or laryngeal mucosa, such as laryngopharyngeal reflux and chronic postnasal drip.
- Trial name
- NCT00381771
- Testing
- Conservative management for xerostomia
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Samsung Medical Center
Non-Hodgkin Lymphoma of Intestine
Multicenter Cross Sectional Study of Primary Intestine Lymphoma
The purpose of this study is to determine whether whether surgical resection followed by chemotherapy is superior to systemic chemotherapy alone in terms of treatment outcome and quality of life (QOL) in patients with primary…
- Trial name
- NCT01043302
- Where
- South Korea
- Volunteers
- 545 people
- Sponsor
- Samsung Medical Center
Nasophayngeal Carcinoma Between Stage II and IVb
A Randomized Phase II Study of Concurrent Chemoradiation With Every 3 Week of Cisplatin vs With Weekly Cisplatin in Locally Advanced Nasopharyngeal Carcinoma
The study try to show the weekly cisplatin based CCRT is not inferior to 3-weekly cisplabe based CCRT in terms of 3-yr progression free survival rate in advanced nasopharyngeal carcinoma
- Trial name
- NCT01171781
- Testing
- cisplatin (3 weekly), cisplatin (weekly)
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center
End Stage Liver Disease, Living Donor
Effect of Intermittent Hepatic Inflow Occlusion During Donor Hepatectomy In Living Donor Liver Transplantation
Intermittent hepatic inflow occlusion (IHIO), also called Pringle maneuver, is a safe and effective procedure for major hepatectomy in patients with liver disease.
- Trial name
- NCT01171742
- Testing
- Intermittent hepatic inflow occlusion (IHIO)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Gastric Adenoma, Gastric Cancer
Efficacy of Bispectral Index Monitoring for Midazolam and Meperidine Induced Sedation During Endoscopic Submucosal Dissection
Background: Endoscopic submucosal dissection (ESD) usually requires adequate level of sedation due to lengthy and uncomfortable procedure.
- Trial name
- NCT01157598
- Testing
- bispectral index monitoring
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Stomach Neoplasms
Phase I Study of Interperitoneal Chenotherapy in Patients With Gastric Adenocarainoma With Peritoneal Seeding
Stomach cancer is the most common cancer, and is still leading cause of death in Korea. Peritoneal seeding is the most common metastases of gastric cancer, and is the most frequent cause of death from this disease.
- Trial name
- NCT00539877
- Testing
- irinotecan
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
Asymptomatic Brain Metastasis in Non-small Cell Lung Cancer (NSCLC)
The prognosis of NSCLC patients with asymptomatic brain metastasis, who are not treated with SRS or WBRT has not been fully investigated yet.
- Trial name
- NCT01130766
- Testing
- stereotactic radiosurgery (SRS)
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Samsung Medical Center
Glaucoma
The Effect of Bevacizumab on the Trabeculectomy
The investigators plan to evaluate the additive effect of intracameral and subconjunctival injections of bevacizumab in trabeculectomies with other antimetabolites.
- Trial name
- bevazicumab (NCT01122966)
- Testing
- intraocular injections of bevacizumab
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer
The Continuation of Erlotinib
Newly developed or progressive brain metastasis during erlotinib treatment is considered progressive disease requiring change of treatment regimens despite no progression in extracranial lesions.
- Trial name
- NCT01130779
- Testing
- Erlotinib (TARCEVA®)
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Samsung Medical Center
Curatively Resected Stage III Colon Cancer
Pharmacogenomic Study to Predict Neurotoxicity of Oxaliplatin
In order to explore genetic factors that may determine the neurotoxicity of oxaliplatin-based chemotherapy, germinal gene polymorphisms will be analyzed.
- Trial name
- NCT00977717
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Endometriosis
Postoperative Cyclic Oral Contraceptive Use for the Prevention of Endometrioma Recurrence
Ovarian endometriotic cyst (endometrioma) is one of the most common endometriotic lesions, and conservative laparoscopic surgery is the treatment of choice. However, the recurrence after surgery is common.
- Trial name
- NCT01092494
- Where
- South Korea
- Volunteers
- 232 people
- Sponsor
- Samsung Medical Center
Acute Lymphoblastic Leukemia
Genome-wide Single Nucleotide Polymorphism (SNP) Array-based Approach to Predict Chemoresponse and Survival in Patients With Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is not a single disease, but a composite of heterogeneous subgroup. Accordingly, more sophisticated classification in ALL is essential to achieve further improvement of treatment outcomes.
- Trial name
- NCT01079507
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Myeloid Leukemia
Genome-wide Pharmacogenetic Candidate Gene Single Nucleotide Polymorphism (SNP) Array-based Approach to Predict Chemoresponse and Survival in Patients With Acute Myeloid Leukemia With Normal Karyotype
The most reliable prognostic marker of acute myeloid leukemia(AML) is cytogenetics by karyotyping. According to cytogenetic results, the patients with AML are classified as better, intermediate and poor prognosis groups.
- Trial name
- NCT01066338
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Myeloid Leukemia
Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid Leukemia
Core binding factor (CBF) positive acute myeloid leukemia (AML) consist of 15% of patients in overall AML, expected to harbor a favorable prognosis. However, around a half of cases relapses.
- Trial name
- NCT01066286
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center