Clinical trials: sponsored by Samsung Medical Center
Chronic Kidney Disease, Proteinuria
The Change of Urinary Angiotensinogen Excretion After Valsartan Treatment in Patients With Persistent Proteinuria
This study is a multicenter, prospective, interventional study. It does not have a control group. All participants will receive 160 mg valsartan for 8 weeks.
- Trial name
- NCT00858299
- Testing
- valsartan
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Coronary Artery Disease
Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion?
We sought to evaluate the long-term safety and efficacy of drug-eluting stent in large vessels compared with bare metal stent.
- Trial name
- COPE (NCT00852215)
- Testing
- Taxus stent, Vision stent
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Clopidogrel Non-Responsiveness
The Comparison of Effects Between Increased Dose of Clopidogrel and Addition of Cilostazol
To compare the effect of increased dosing of clopidogrel and adding cilostazol to standard dose of clopidogrel after the insertion of drug-eluting stent in patients with clopidogrel resistance
- Trial name
- 4C-DES (NCT00620646)
- Testing
- aspirin, clopidogrel, aspirin, clopidogrel, cilostazol
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Gastric Cancer
A Phase I/II Trial of Docetaxel and Oxaliplatin in Patients With Advanced Gastric Cancer
Gastric cancer is the most common malignancy in Korea. The prognosis of unresectable gastric cancer has been improved by cytotoxic chemotherapy, but median survival rarely exceeds 1 year.
- Trial name
- DO for AGC (NCT00533533)
- Testing
- docetaxel, oxaliplatin
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Samsung Medical Center
Gastric Cancer Patients Treated by Subtotal Gastrectomy
Obestatin Change in Distal Gastrectomy
According to Seoul cancer registry data (2000), cancer became the leading cause of death in Korea, accounting for 23.9% of all deaths and gastric cancer is the most prevalent malignant neoplasm, comprising 20.8% of all cancers.
- Trial name
- NCT00822718
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
AML, MDS
Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine, Busulfan, and Total Body Irradiation (TBI)
The purpose of this study is to evaluate the OS, RFS, and TRM after HCT with low-dose total body irradiation, fludarabine, and busulfan conditioning.
- Conditions
- AML, MDS, ALL, CML
- Trial name
- NCT00815568
- Testing
- fludarabine phosphate, busulfan
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Samsung Medical Center
Obesity, Prader-Willi Syndrome
Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi Syndrome
The inflammatory process is involved in the pathogenesis of obesity. Prader-Willi syndrome (PWS) is a genetic model of syndromic obesity.
- Trial name
- NCT00800852
- Volunteers
- healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Neuroblastoma, Brain Tumor
Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation
The purpose of this study is to investigate whether the prophylactic use of itraconazole is a better option than empirical use of itraconazole in the management (prevention and treatment) of fungal infection associated with…
- Conditions
- Neuroblastoma, Brain Tumor, Retinoblastoma, Wilms Tumor
- Trial name
- NCT00336531
- Testing
- itraconazole
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Prostate Cancer
A Prospective Longitudinal Study of Health-Related Quality of Life in Men With Clinically Localized Prostate Cancer
to prospectively assess the health-related quality of life (HRQOL) changes during the first year after different treatment modalities for localized prostate cancer.
- Trial name
- NCT00777452
- Where
- South Korea
- Volunteers
- 93 people
- Sponsor
- Samsung Medical Center
Radical Perineal Prostatectomy
A Capsular Incision and Biochemical Recurrence After Radical Perineal Prostatectomy
To evaluate the impact of capsular incisions on biochemical recurrence (BCR) and the potential risk factors of capsular incisions.
- Trial name
- NCT00748514
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome
Effects of Intensive Lipid Lowering and Omega-3 Fatty Acid on Composition of Coronary Atherosclerotic Plaque
The purpose of this study is to determine whether intensive lipid lowering and Omega-3 fatty acid are effective in the treatment of coronary atherosclerotic plaque.
- Trial name
- NCT00760786
- Testing
- Intensive lipid lowering plus Omega3-fatty acid, Moderate lipid lowering plus Omega3-fatty acid
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Immunity
Prospective Comparison of Immunological Benefit of Laparoscopic Colectomy
This study aimed to clarify existence of immunological benefit of laparoscopic colon cancer surgery compared to open colon surgery.
- Trial name
- NCT00744159
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Samsung Medical Center
Myopia
The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test
The purpose of this study is to examine the effect of the myopic optical defocus on the Humphrey Matrix 30-2 test.
- Trial name
- NCT00638430
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Presbyopia, Cataract
The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
- Trial name
- NCT00624039
- Testing
- UBM with pilocarpine in presbyopia
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Samsung Medical Center
Acute Myocardial Infarction
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
The purpose of this study to investigate whether the administration of high-dose tirofiban before primary PCI could reduce myocardial infarct size, using analysis of contrast-enhanced magnetic resonance imaging.
- Trial name
- NCT00611169
- Testing
- tirofiban
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Coronary Artery Bypass
Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery
The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.
- Trial name
- NCT00611143
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Rectal Neoplasm, Surgical Stapler
Randomized Comparison of Curved Cutter Stapler and Linear Stapler
This study aims to compare the safty and technical accessibility of linear stapler and curved cutter stapler during mid to low rectal cancer surgery.
- Trial name
- NCT00549276
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Stroke
fMRI Study of Brain Neural Network and Plasticity After Stroke
The purposes of this study are to investigate the functional connectivity of motor network in patients of stroke and investigate the mechanism of brain plasticity for recovery after stroke.
- Trial name
- NCT00530647
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Stroke
Effect of Donepezil on the Reorganization of Cognitive Neural Network in Patients With Post-Stroke Cognitive Impairment
The purpose of this study is to demonstrate the efficacy and safety of donepezil on the recovery of cognitive function in patients with stroke and to delineate the neurophysiologic mechanisms of the therapeutic effect of…
- Trial name
- NCT00530478
- Testing
- Donepezil
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Capsule Endoscopy
Capsule Endoscopic Miss Rates Determined by Back-to-Back Capsule Endoscopy
The purpose of this study is to determine the missing rate of capsule endoscopy using back-to-back capsule endoscopy.
- Trial name
- NCT00530231
- Where
- South Korea
- Sponsor
- Samsung Medical Center