Clinical trials: sponsored by Seattle Children's Hospital
Chronic Pain, Abdominal Pain
Problem Solving Skills Training For Parent Caregivers of Youth With Chronic Pain
The purpose of this study is to evaluate the feasibility and efficacy of problem-solving skills training (PSST) to reduce distress and increase coping abilities among parents of youth with chronic pain.
- Conditions
- Chronic Pain, Abdominal Pain, Headache
- Trial name
- NCT01496378
- Testing
- Problem-Solving Skills Training
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Seattle Children's Hospital
Adolescent Behavior
I-ACT With Check Yourself
Adolescents have some of the highest rates of risk behaviors of all age groups and health behaviors developed in adolescence can persist into adulthood.
- Trial name
- NCT02764190
- Testing
- I-ACT with Check Yourself
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Malaria
Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria Vaccine
The purpose of this study is to assess safety and tolerability of escalating doses of a genetically attenuated parasite malaria vaccine (p52-/p36- GAP vaccine) in healthy malaria-naive adults.
- Trial name
- NCT01024686
- Testing
- p52-/p36- GAP Vaccine, p52-p36- GAP Vaccine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Preventive Health Services
Screening for Hesitancy to Optimize Talk
The overall goal of this project is to determine whether integrating a novel parent-report measure of vaccine hesitancy into pediatric primary care is effective in improving acceptance of childhood vaccines among vaccine-hesitant…
- Trial name
- SHOT (NCT02708745)
- Testing
- Intervention Survey
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Sexual Behavior, Conflict, Family
Heart to Heart: Testing a Sexual Health Training for Foster and Kinship Caregivers
Heart to Heart is a brief pregnancy prevention training program delivered to foster and kinship caregivers to prevent unintended pregnancy in foster youth.
- Conditions
- Sexual Behavior, Conflict, Family, Pregnancy Related, Sexually Transmitted Diseases
- Trial name
- NCT03331016
- Testing
- Heart to Heart Training
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Peripherally Inserted Central Catheters
Point of Care Ultrasound for PICC Line Monitoring Study
A prospective comparative study evaluating chest x-ray determination of PICC line tip location and POC ultrasound PICC line tip location.
- Trial name
- PUP (NCT03954977)
- Testing
- PICC line ultrasound
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Acute Respiratory Tract Infection
Reducing Antibiotic Prescribing in Family Practice
Antibiotic prescribing for childhood acute respiratory tract infections (ARTIs), including acute otitis media (AOM), pharyngitis, sinusitis, bronchitis, and upper respiratory infection (URI), is common in the United States (US).
- Trial name
- NCT03674775
- Testing
- DART QI Program Participation
- Volunteers
- 180 people
- Sponsor
- Seattle Children's Hospital
Respiratory Disease, Acute Respiratory Infection
Dialogue Around Respiratory Illness Treatment
Unwarranted use of antibiotics for pediatric acute respiratory tract infections (ARTIs) and use of second-line, broad spectrum antibiotics for bacterial ARTIs has contributed to the rapid development of resistance in many strains…
- Conditions
- Respiratory Disease, Acute Respiratory Infection, Respiratory Infection, Upper Respiratory Infection
- Trial name
- DART (NCT02943551)
- Testing
- Online Tutorial, Webinars, Booster Sessions
- Where
- 20 sites in United States
- Volunteers
- 2,728 people
- Sponsor
- Seattle Children's Hospital
Cerebral Palsy Spastic Diplegia
Cerebral Palsy: Short-burst Interval Training
This study examines the effect of short burst interval treadmill training in ambulatory children with cerebral palsy. Half the sample will receive 20 sessions of training over 4 weeks, while half will receive the training over 10…
- Trial name
- NCT03373890
- Testing
- Short Burst Interval Locomotor Treadmill Training (SBLTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Seattle Children's Hospital
Chronic Pain
WebMAP Mobile Self-management of Adolescent Chronic Pain
Approximately 5-8% of children report severe chronic pain and disability. Although evidence supports pain-self management as effective for reducing pain and disability, data show that most youth do not have access to this…
- Trial name
- NCT03332563
- Testing
- Cognitive-behavioral intervention for chronic pain
- Where
- 5 sites in United States
- Volunteers
- 143 people
- Sponsor
- Seattle Children's Hospital
Crohn's Disease
Nutritional Therapy Study in Pediatric Crohn's Disease
The investigators are doing this research study to answer questions about a nutritional therapy called the Specific Carbohydrate Diet (SCD) for children with active Crohn's Disease (CD).
- Trial name
- NCT02610101
- Testing
- Traditional SCD Diet, Modified SCD Diet, Whole foods diet
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Seattle Children's Hospital
Unspecified Childhood Solid Tumor, Protocol Specific
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003194
- Testing
- filgrastim, carboplatin, cyclophosphamide
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Acute Kidney Injury
AKI Management Using Electronic Alerts
Acute kidney injury (AKI) is a common clinical event with severe consequences. In the United States alone, greater than one million hospitalized patients per year are diagnosed with AKI.
- Trial name
- NCT03538769
- Testing
- electronic alert and clinical decision support system
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Seattle Children's Hospital
Physical Activity
Preschoolers Active at Child Care (PACT)
The aim of this study was to develop, test, and compare two approaches to increasing physical activity (PA) and decreasing sedentary time among young children at child care centers, one which focused on a teacher-led PA…
- Trial name
- PACT (NCT03752008)
- Testing
- Active Play (AP), Outdoor Play (OP)
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Anxiety
Improving Sedation of Children Undergoing Procedures in the Emergency Department
Lacerations (deep cuts) are a frequent cause of visits to emergency departments and laceration repair is one of the most common procedures performed in that setting.
- Trial name
- NCT00675909
- Testing
- Aerosolized Intranasal midazolam, Aerosolized Buccal Midazolam, Oral midazolam
- Volunteers
- 180 people
- Sponsor
- Seattle Children's Hospital
Persistent Concussion Symptoms
Study of an Exercise Program (STEP) for Youth With Concussion
To compare the efficacy of a sub-threshold aerobic exercise intervention provided with mobile health coaching (STEP-mhc) and a light stretching program (LS) to LS alone for 11-18 yo youth with persistent concussion symptoms.
- Trial name
- STEP (NCT02673112)
- Testing
- Subthreshold exercise (STEP) with mobile health coaching, Light stretching (LS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Seattle Children's Hospital
Attention Deficit Hyperactivity Disorder
Sequencing Treatments for Mothers With ADHD and Their At - Risk Children
We hypothesize that successfully treating maternal Attention Deficit Hyperactivity Disorder (ADHD) will have a beneficial effect that extends to the child.
- Trial name
- TMF (NCT01816074)
- Testing
- Vyvanse (lisdexamphetamine), Behavior Parent Training
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Seattle Children's Hospital
Hemangioma
Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH)
This is a prospective randomized, double-blind study to compare the clinical efficacy of infantile hemangioma treatment using propranolol with corticosteroids as compared to therapy with corticosteroids and placebo.
- Trial name
- NCT01074437
- Testing
- Prednisolone (Corticosteroid), Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Seattle Children's Hospital
Chronic Pain, Abdominal Pain
Internet Intervention for Adolescents With Chronic Pain
The purpose of this study is to evaluate the efficacy of a web-based (i.e., internet) behavioral program to reduce pain and improve functioning in children and adolescents with chronic pain.
- Conditions
- Chronic Pain, Abdominal Pain, Headache
- Trial name
- NCT01316471
- Testing
- Online Behavioral Intervention, Education: Online Patient Education
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Seattle Children's Hospital
Concussion
Care for Post-Concussive Symptoms
The proposed study is a pilot randomized trial of a stepped collaborative care intervention designed to decrease post-concussive symptoms and improve post-injury functioning among sports-injured youth aged 11-17.
- Trial name
- CARE4PCS (NCT02268240)
- Testing
- Stepped Care
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Seattle Children's Hospital