Clinical trials: sponsored by Sheba Medical Center
Focused Stress
Identification and Comprehension of Focused Stress in a Sentence Among Adults Who Suffered Traumatic Brain Injury
Researches that focus on the perception of prosodic elements among adult who suffered traumatic brain injury (TBI), focus on their ability to decipher intonation in order to understand an additional meaning of a sentence.
- Trial name
- NCT02499133
- Testing
- language and cognitive tests
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obesity, Diabetes
The Long Term Effect of Adjustable Spaatz 3 Intragastric Balloon on Weight Loss
This is an open-label trial investigating the effect of Spatz 3 intragastric balloon on weight loss on obesity and associated co- morbidities.
- Conditions
- Obesity, Diabetes, Hypertension
- Trial name
- NCT02003872
- Testing
- Spatz 3 intragastric balloon
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Sheba Medical Center
Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma
Mozobil for Autologous Stem Cell Mobilization
The aim of this study is to evaluate Plerixafor (MOZOBIL) plus recombinant human G-CSF (G-CSF) efficiency in mobilizing sufficient number of stem cells from Lymphoma (NHL and HL) patients for autologous transplantation.
- Conditions
- Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Stem Cell Mobilization, Autologous Stem Cell Transplantation
- Trial name
- NCT01164345
- Testing
- Plerixafor
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Graft-versus-host Disease
Carfilzomib for the Prevention of Graft Versus Host Disease
The aim of this study is to evaluate the safety and efficacy of Carfilzumib, which is a novel biological agent used in the treatment of multiple myeloma in preventing graft-versus-host disease, after stem cells transplantation…
- Trial name
- NCT01991301
- Testing
- carfilzumib
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Oligozoospermia, Azoospermia
The Effect of Low Electrical Current on Testicular Spermatocyte Count
Oligozoospermia, refers to a low concentration of sperm. A low sperm count or poor sperm quality is the cause of infertility in about 20% of couples with fertility problems, and a contributory factor in a further 25% of couples.
- Trial name
- NCT02617173
- Testing
- Micro 400 Matrix Therapy Products
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Pain
Open Prospective Study for Determination of Predictive Measures for Pain During Colonoscopy
The aim of the study is to determine what precolonoscopic measures can be correlated to pain during colonoscopy
- Trial name
- NCT01496560
- Where
- Israel
- Sponsor
- Sheba Medical Center
Pain
Pretreatment With Electroacupuncture to Reduce Discomfort
The main hypothesis is that performance of electroacupuncture before colonoscopy reduces pain during the exam.
- Trial name
- NCT02077270
- Testing
- electroacupuncture
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Anorexia Nervosa, Bulimia Nervosa
Common Decision Making Deficits in Suicidal Behaviors and Eating Disorders
The role of impulsivity and its contribution to suicidal behavior seems intuitively clear. Empirical results have proved the existence of a relationship between the two yet many questions are left unanswered, especially what…
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Suicide, Parasuicide
- Trial name
- NCT02595164
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Multiple Sclerosis
Deciphering the Role of the Gut Microbiota in Multiple Sclerosis
Multiple sclerosis (MS) is an inflammatory disease that affects the nervous system and results in a wide range of signs and symptoms including physical and cognitive problems.
- Trial name
- NCT02580435
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pregnancies of Unknown Location (PUL)
A Prospective Study of Misoprostol Administration in Asymptomatic Patients With Pregnancies of Unknown Location
A randomized prospective double blind study of misoprostol administration in asymptomatic patients with pregnancies of unknown location.
- Trial name
- amalis (NCT02581761)
- Testing
- CYTOTEC
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Rectal Neoplasms
Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer
Locally advanced rectal cancer (T3, T4 or lymph node positive tumors) are conventionally treated with 5FU / capecitabine based chemoradiation prior to surgical resection.
- Trial name
- NCT02137356
- Testing
- standard dose pelvic radiation therapy, standard dose capecitabine, dose-escalated selinexor treatment
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Sheba Medical Center
Congestive Heart Failure
Non-Invasive Cardiac Output Measurement for CRT Optimization
This proposal aims to evaluate the added clinical and echocardiographic benefit of using the non-invasive impedance-based cardiac output measurement system (NICaS) for optimizing atrio-ventricular and inter-ventricular delays in…
- Trial name
- NICaS-CRT (NCT02126241)
- Testing
- NICaS guided CRT optimization
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Sheba Medical Center
Functional Neural Connectivity
Functional Neural Connectivity at Rest as a Diagnostic Tool for Intolerance to Heat
Functional neural connectivity at rest of 3 groups (heat tolerant, heat intolerant and healthy subjects) will be assessed using the anatomical and functional MRI scans and compared.
- Trial name
- fMRI (NCT02498158)
- Testing
- MRI scans
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Work Load
Adjusting the Load Carried by the Soldier According to Body Composition Measurements and Aerobic Capacity
In order to reduce the physiological and biomechanical loads that the soldiers are exposed to, the investigators want to examine new approaches for distributing the carried loads according to measurements that are specific for…
- Trial name
- LCI (NCT02498223)
- Testing
- experiment protocol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Rhabdomyolysis
Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty
In order to determine norm values for skeleton muscle disassembly due to physical exertion in healthy and trained population, and developing a prediction test for approval for rhabdomyolysis injuries to return to duty, 50 healthy…
- Trial name
- NCT02498366
- Testing
- physical tests
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Motor Activity
Classification and Characterization of Physical Strains During Sorting Series: Physiological Aspects
2 young candidates have tragically died during army pre-recruitment sorting series in 2006. As part of the classification and characterization of the physical aspects of the training, this experiment was requested.
- Trial name
- NCT02476344
- Testing
- experiment protocol
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Creutzfeldt-Jakob Syndrome
The Role of the Coagulation Pathway at the Synapse in Prion Diseases
The study hypothesis is that that the deleterious effect of prions on the brain may be mediated (at least partially) by activation of serine proteases involved in the coagulation system.
- Trial name
- NCT02480725
- Testing
- collect CSF (Cerebrospinal fluid) sample
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Obesity
CNS Modification of Food Craving by Neurofeedback
The investigators plan to evaluate H.E.G. (Hematoencephalography) modality in brain modulation of appetite and food craving in a randomized controlled study. The H.E.G.
- Trial name
- NCT02480179
- Testing
- H.E.G. (hematoencephalography) based neurofeedback
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Panic Disorder, Proprioceptive Disorders
The Assessment and Treatment of Balance Impairment Using Virtual Reality (VR) in Panic Disorder Patients
Hypotheses The investigators hypothesize that among individuals who suffer from panic disorder there is higher incidence of co-morbid balance impairment than in the healthy population.
- Trial name
- NCT01677429
- Testing
- VR movie + balance challenge, still pictures from VR, Cognitive Behavioral Therapy
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke
Virtual Reality Intervention for Stroke Rehabilitation
In Israel approximately 16,000 people have a stroke each year. Most of these people suffer from weakness or paralysis of half of their body which leads to difficulties performing basic activities of daily life (BADL) such as…
- Trial name
- NCT01304017
- Testing
- Virtual Reality, Traditional Therapy
- Volunteers
- 47 people
- Sponsor
- Sheba Medical Center