Clinical trials: sponsored by Sheba Medical Center
Surgical Site Infections
Antibiotic Prophylaxis in Prosthetic Breast Reconstructions
The added benefit of prolonged antibiotic prophylactic treatment in patients undergoing breast reconstruction who have drains placed for several days after surgery is controversial.
- Trial name
- NCT02012517
- Testing
- Prolonged antibiotic treatment, Short antibiotic course (standard of care)
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Sheba Medical Center
Oxytocin + Non Specific Counselling, Oxytocin + Social Skills Training
Administrating Oxytocin to Treat Treatment Schizophrenia and Schizo-affective Patients
The objectives of the study are: 1. To evaluate the effect of OT compared to placebo, as add-on to anti-psychotics, on social functioning in schizophrenia. 2.
- Conditions
- Oxytocin + Non Specific Counselling, Oxytocin + Social Skills Training, Placebo + Non Specific Counselling, Placebo + Social Skills Training
- Trial name
- OXY-S-01 (NCT01598623)
- Testing
- Oxytocin, Social Skills Training
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Sheba Medical Center
Hereditary Breast and Ovarian Cancer Syndrome
Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers
Breast cancer (BC) is a major health problem and the most prevalent cancer among women.In a substantial proportion of familial cases, germ-line mutations in either BRCA1/2 can be detected.
- Trial name
- NCT01367639
- Testing
- Inquiry Based Stress Reduction (IBSR) program
- Where
- Israel
- Volunteers
- 67 people
- Sponsor
- Sheba Medical Center
Body Weight Changes, Feeding and Eating Disorders of Childhood
Adjusted Individual Oral Feeding for Improving Short and Long Term Outcomes of Preterm Infants
The authors hypothesize that adjusted individual feeding (AIF) for preterm infant starting from transition to oral feeding (33 weeks corrected age) will result in less episodes of apnea/bradycardia, early achievement of full oral…
- Conditions
- Body Weight Changes, Feeding and Eating Disorders of Childhood, Breast Feeding, Evoked Response Audiometry
- Trial name
- NCT01989871
- Testing
- Adjusted individual feeding
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Ventricular Tachyarrhythmia
Change in Heart Rate Variability Prior to Tachyarrhythmia in ICD Implanted Patients
To investigate changes in HRV during the time before a spontaneous episode of ventricular tachyarrhythmia.
- Trial name
- HRV (NCT00701467)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Cystic Fibrosis
Improving Adherence and Clinical Outcome in Cystic Fibrosis (CF) Patients
The purpose of this study is to assess the impact of a collaborative active intervention program of a multi-disciplinary team on improving adherence to chronic medications and improve clinical outcomes in CF patients.
- Trial name
- NCT01025258
- Testing
- Frequent Scheduled CF clinic visits, frequent telephone calls to patients pre and post visits to the clinic
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Sheba Medical Center
Heart Failure
Outcome and Safety of Intermittent Dobutamine Infusion at a Day-Care Center in Advanced Heart Failure Patients
Heart failure (HF) is a prevalent disease reaching 1-2% of adult population in developed countries, and 10% in patients over 70 years.
- Trial name
- DoBHF (NCT01930734)
- Testing
- Dobutamine, Normal Saline
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
NSCLC
An Open Label Study of BIBW 2992/Afatinib in Advanced Non-Small Cell Lung Cancer Patients Pre-treated With Erlotinib or Gefitinib
Advanced lung cancer (non-small cell lung cancer) with a mutation in the EGFR (epidermal growth factor receptor) gene, which have disease progression after treatment with an EGFR inhibitor (erlotinib or gefitinib), and have…
- Trial name
- NCT01932229
- Testing
- Afatinib treatment
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Posttraumatic Stress Disorders, Cortisol Diurnal Variation
Cortisol Diurnal Variation and the Risk for Developing Post Traumatic Stress Disorder
The purpose of this study is to examine a possible link between the time of day of exposure to a traumatic event and the risk of developing post-traumatic stress disorder.
- Trial name
- NCT01914861
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Lung Neoplasms
Identifying Unique Scent Signature of Lung Cancer Through Body Odor
The purpose of this study is to show that dogs are able to detect cancer in sweat samples. This potentially would be the base for developing a new efficient, non invasive and inexpensive diagnosis tool of lung cancer.
- Trial name
- NCT01527461
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Intra Cerebral Hemorrhage
Feasibility Study of New MRI Protocol in Assessing Early Blood Brain Barrier Disruption (BBBD)in Related to Delay Brain Edema
MRI research Group in the Advanced Technology Center of the Sheba Medical Center has developed an innovative methodology based on leakage (extravasation) contrast agent that allows to map the entire brain with high resolution and…
- Trial name
- BBBD (NCT01830894)
- Testing
- MRI
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Conservatively Treated CHI Patients
Long Term Glucose Metabolism in Conservatively Treated Patients With Congenital Hyperinsulinism
The purpose of this study is to continue follow up of conservatively treated CHI patients and to focus on their metabolic outcome, including frequency of hypoglycemia after discontinuing treatment and incidence of diabetes…
- Trial name
- NCT01819584
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Evaluation of the Efficacy of Hippotherapy for Children With Developmental Disorders
Hippotherapy is every program of horseback riding meant to treat people with physiological, mental, social, cognitive or behavioral problems.
- Trial name
- NCT00717392
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Chorioamnionitis, Cerebral Palsy
Early Identification of Brain Insult in Chorioamnionitis
Premature breaking of the amniotic fluids during pregnancy caries high risk for infection of the amniotic fluid. One of the results of chorioamnionitis is brain injury of the fetus.
- Trial name
- NCT01778725
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
PTSD
Prolonged Exposure (PE) Treatment for Post Traumatic Stress Disorder (PTSD) 20 Minutes Versus 40 Minutes
Comparing the efficacy of 40 minutes PE treatment to 20 minutes of the same treatment
- Trial name
- NCT00229307
- Testing
- Prolonged Exposure (PE) therapy
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- Sheba Medical Center
Parents Approval to Research
Mothers' Approach to Clinical Research Amongst Their Preterm or Healthy Newborns
Parental approval to enroll their sick children in clinical research was studied. However, the motivation of parents to enroll healthy children and/or babies was not yet studied.
- Trial name
- NCT00332150
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Psoriasis
The Effect of Algae Dunaliella Bardawil on Psoriasis (2)
This is a Randomized, Double-Blind, , Placebo Controlled, 18 Week Study To Evaluate the Efficacy of adjuvant 9-cis-β-Carotene Rich powder of the Alga Dunaliella bardawil in Subjects With Plaque type Psoriasis treated by Narrow…
- Trial name
- NCT01121081
- Testing
- Alga Dunaliella Bardawil
- Where
- Israel
- Sponsor
- Sheba Medical Center
Detection of the Correct Position of Intravenous Line
Intravenous Bicarbonate To Verify The Correct Position of IV Catheters in Oncological Patients Oncological Patients Receiving Chemotherapy
The investigators use bicarbonate injected to an intravenous line and the changes in the exhaled end-tidal carbon dioxide to verify whether the IV line is in the vein or surrounding tissue
- Trial name
- IVBICONCOL (NCT01748097)
- Testing
- sodium bicarbonate 4.2%
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Trigeminal Neuralgia, Tic Douloureux
Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain
The "Suicide Disease", Trigeminal Neuralgia (TN) is arguably caused by one of the most discrete and eloquently reversible central nervous system lesions known to the field of neurology. Recently Dr Adahan H. and Dr Binshtok A.
- Trial name
- NCT01447108
- Testing
- Low Intensity Low Frequency Surface Acoustic Wave Ultrasound (PainShield™)
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Sheba Medical Center