Clinical trials: sponsored by Shengjing Hospital
White Matter Injury
Brain White Matter Injury in Late Preterm Infants
At 34 weeks, the brain weight of preterm infants is only 65% that of term infants, and the cortex volume is 53% that of term infants.
- Trial name
- NCT04508517
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Shengjing Hospital
Postoperative Delirium, General Anesthesia
The Disorder of Circadian Clock Gene and Early Cognitive Dysfunction After General Anesthesia
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in patients aged 65 and over, which refers to cognitive function changes such as memory decline and attention deficit after anesthesia and surgery.
- Conditions
- Postoperative Delirium, General Anesthesia, Exosomes, Clock Gene
- Trial name
- NCT04421872
- Testing
- receiving general anesthesia
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Carotid Artery Diseases, Healthy Volunteers
Multicenter Normal Reference Study of Carotid Artery Ultrafast Pulse Wave Velocity (UFPWV)
To establish the range of BS and ES (m/s) of normal carotid artery by using ultrafast pulse wave velocity (UFPWV), and to explore the influencing factors.
- Trial name
- NCT03351127
- Testing
- Carotid ultrasound examination
- Where
- 44 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Infectious Diseases in Pneumonia,Nephropyelitis,Angiocholitis or Others, Positive Bacterial Cultures Results of the Medical Records
Bacterial and Antimicrobial Susceptibility Profile and the Prevalence of Different Sites of Infection(BASPP)
Positive results of bacterial culture are analyzed comprehensively in Shengjing Hospital of China Medical University in recent 3 years（between 2015- 2017）
- Trial name
- NCT03333863
- Testing
- descriptive study which reviewed the data of patients hospitalized with positive bacterial cultures
- Where
- China
- Volunteers
- 1,889 people
- Sponsor
- Shengjing Hospital
Morning Operation, Evening Operation
Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
General anesthesia is a medically induced state of low reactivity consciousness involving amnesia, immobility, unconsciousness, and analgesia, which is similar to natural sleep.
- Conditions
- Morning Operation, Evening Operation, Sleep Quality, General Anesthesia
- Trial name
- NCT04094376
- Testing
- receiving operation during the day or at night
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Gastroesophageal Reflux, Bronchopulmonary Dysplasia
GER Poses a Potential Risk for Late Complications of BPD
Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the…
- Trial name
- NCT03014453
- Where
- China
- Volunteers
- 187 people
- Sponsor
- Shengjing Hospital
Low Back Pain
Transpubic Symphysis Reset for Treatment of Low Back Pain
To verify the efficacy of transpubic symphysis reset therapy for low back pain, and provide support for the clinical application of this treatment.
- Trial name
- NCT02906540
- Testing
- Transpubic symphysis reset therapy group, Physiotherapy group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Breast Cancer
Positive Node Traced Before Neoadjuvant Chemotherapy (NAC)
To investigate this regression model by injecting and tracing carbon nanoparticles (CNs) into the fusion node prior to NAC in patients with breast cancer.
- Trial name
- NCT03355261
- Testing
- complete remission (CR) group, partial remission (PR) group, stable disease (SD) group
- Where
- 3 sites in China
- Volunteers
- 110 people
- Sponsor
- Shengjing Hospital
Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy
Birth Cohort Study of China Medical University
The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology.
- Conditions
- Twin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity
- Trial name
- NCT03561766
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Circadian Clock, Postoperative Cognitive Function
The Effect of Circadian Clock System on Perioperative Cognitive Function of Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in patients aged 65 and above. It refers to the cognitive function changes such as memory decline and attention loss after anesthesia and surgery.
- Conditions
- Circadian Clock, Postoperative Cognitive Function, General Anesthesia, Elderly Patients
- Trial name
- NCT04194866
- Testing
- receiving operation during the day or at night
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Cardiovascular
Comparison of Effects of Oxycodone and Sufentanil on Cardiovascular Stress Induced by Tracheal Intubation in the Patients With Coronary Heart Disease Undergoing Major Noncardiac Surgery
To evaluate the effect of oxycodone and sufentanil in preventing cardiovascular responses to tracheal intubation in the patients with coronary heart disease (CHD).
- Trial name
- NCT04121416
- Testing
- Oxycodone 10mg, Sufentanil
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Postoperative Pain, Postoperative Sleep Quality
The Effect of Intraoperative Use of Dexmedetomidine During the Daytime Operation vs the Nighttime Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
General anesthesia is a medically induced state of low reactivity consciousness which is similar to natural sleep. Some studies found that general anesthesia as an independent risk factor could result in a desynchronization of…
- Conditions
- Postoperative Pain, Postoperative Sleep Quality, Intraoperative Dexmedetomidine, General Anesthesia
- Trial name
- NCT03990987
- Testing
- time of receiving operation
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Shengjing Hospital
Preoperative Anxiety, Precise Dose of Butorphanol
Using Preoperative Anxiety Score to Determine the Precise Dose of Butorphanol for Sedation
Pre-operative anxiety usually lead to increased anesthetics during the surgery. The precise sedative requirement which can keep adequate sedative state and avoid adverse effects caused by excessive drugs still needs further…
- Trial name
- NCT03429179
- Testing
- Butorphanol, Physiological saline
- Where
- China
- Volunteers
- 155 people
- Sponsor
- Shengjing Hospital
Arrhythmia
Efficacy and Safety of Sotalol in Children With Arrhythmia
This study aims to investigate the efficacy and safety of oral sotalol alone or combination with other anti-arrhythmic medicines in the treatment of arrhythmias in children.
- Trial name
- NCT03895411
- Testing
- sotalol, Propafenone, betaloc
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shengjing Hospital
Children AKI Patients
The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury
Acute kidney injury (AKI) is a pervasive clinical event in children.It has been independently associated with prolonged hospital stays, risk of in-hospital death and future progression to chronic kidney disease.
- Trial name
- NCT03892447
- Testing
- Alprostadil, Sodium Ferulate, Dopamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shengjing Hospital
0.5-14 Year Old Children With Nephroblastoma
Combination Therapy of Anthracyclines for Children With Nephroblastoma
This study aims to estimate the efficacy and side effects of study drugs in children with nephroblastoma who are treated with combination therapy.
- Trial name
- NCT03892330
- Testing
- Vincristine, Oxytetracycline/ Cyclophosphamide, Liposomal doxorubicin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shengjing Hospital
Preoperative Anxiety Score, Total Dose of Butorphanol
Using Preoperative Anxiety Score to Determine the Total Dose of Butorphanol for Sedation
Orthopedic surgeries are considered to be discomfortable and the sense of fear and anxiety of patients who already have preoperative anxiety may be aggravated by intraoperative stimulation, which may contribute to postoperative…
- Trial name
- NCT03810391
- Testing
- Butorphanol, physiological saline
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Shengjing Hospital
Twin Diseases
Diagnosis and Intervention of Complicated Twin Diseases
Fetal medicine in China is still a new, young discipline, and the development is very rapid. After nearly 10 years of development, the clinical diagnosis and treatment guidelines of some complicated twin diseases has been…
- Trial name
- NCT03650985
- Testing
- Fetoscope technique
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Coronary Heart Disease
Prospective Evaluation of Prognosis of Pci Patients Using Network Data in SHengjing Hospital
Coronary heart disease (CHD) has a serious health threaten to population. PCI is a well-proved measure in CHD management. However, the knowledge about the real-life PCI use and how evidence-based therapies in routine clinical…
- Trial name
- P-PUSH (NCT02667548)
- Testing
- PCI
- Volunteers
- 7,000 people
- Sponsor
- Shengjing Hospital
Stress
Effects of TEAS on Stress Response During Extubation of General Anesthesia in Elderly Patients
Elderly patients have an increased risk of stress responses during extubation after general anaesthesia for an elective supratentorial craniotomy.
- Trial name
- NCT02533388
- Testing
- Hwato Electronic Acupuncture Treatment Instrument
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital