Clinical trials: sponsored by Sir Run Run Shaw Hospital
Mechanical Ventilation, Atelectasis
To Assess the Effectiveness of Three Distinct Mechanical Assisted Sputum Evacuation Apparatuses in the Treatment of Patients With Mechanical Ventilation-induced Atelectasis
Retention of airway secretions is a common clinical problem in patients with mechanical ventilation. Effective removal of airway secretions requires a balance between the production and removal of airway secretions through the…
- Trial name
- EOTEOMASE (NCT06631716)
- Testing
- CVT, HFCWO, MetaNeb
- Volunteers
- 84 people
- Sponsor
- Sir Run Run Shaw Hospital
Trauma Injury, Acute Coronary Syndrome
Smart Glasses in Emergency Medicine From the Hangzhou Asian Games
The findings of our study will reveal that using smart glasses in the emergency department(ED) could facilitate patient admission. AR Smart Glasses offer the potential to enhance the effectiveness and speed of treatment within ED.
- Conditions
- Trauma Injury, Acute Coronary Syndrome, Stroke, Acute, Septic Shock
- Trial name
- SGINHZAG (NCT06623825)
- Testing
- teleconsultation by Augmented Reality smart glasses, teleconsultation by two-way radio connection.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sir Run Run Shaw Hospital
Microsatellite Stable (MSS) Colon Cancer, Locally Advanced Colon Cancer
Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study
This study aims to evaluate the use of node-sparing short-course radiotherapy combined with chemotherapy and Sintilimab, or chemotherapy alone, as neoadjuvant therapy for MSS-type locally advanced colon cancer.
- Trial name
- mRCAT-C (NCT06594692)
- Testing
- Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab, CAPOX Chemotherapy
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Sir Run Run Shaw Hospital
Locally Advanced Colorectal Cancer, Postoperative Adjuvant Therapy
Evaluating the Benefits of Personalized Traditional Chinese Medicine in Postoperative Treatment for Locally Advanced Colorectal Cancer
This study aims to explore the role of Traditional Chinese Medicine (TCM) based on syndrome differentiation in reducing chemotherapy side effects, lowering the risk of metastasis and recurrence, and improving survival rates in…
- Trial name
- NCT06596343
- Testing
- Adjuvant Chemotherapy Combined with Traditional Chinese Medicine (TCM) Supportive Therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sir Run Run Shaw Hospital
Efficacy, Self, Safety Issues
First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer
This is a prospective, multi-center, randomized controlled clinical intervention study, aiming to explore the effectiveness and safety of mfolfox6 and hlx04 regimens combined with slulimumab as first-line treatment for MSS-type…
- Conditions
- Efficacy, Self, Safety Issues, Colo-rectal Cancer
- Trial name
- NCT06491355
- Testing
- mfolfox6 and hlx04 regimen and Serplulimab, mfolfox6 and hlx04 regimen
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Sir Run Run Shaw Hospital
Emergency Medicine, Telemedicine
Integration of the 5G-based Remote Healthcare System in Critical Care
The primary objective of this initial report is to address the following questions: Under what circumstances do clinical teams at satellite locations utilize the 5G RHS? Does the implementation of 5G RHS result in significant…
- Conditions
- Emergency Medicine, Telemedicine, Augmented Reality
- Trial name
- IT5GRHSCI (NCT06485518)
- Testing
- The 5G RHS group receiving audio-video conferencing and effective data management for decision-making via augmented reality platform RealHealthcare System.
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Sir Run Run Shaw Hospital
Schizophrenia
The Hi-tACS on Cognitive Function in Patients With Schizophrenia: a Pilot Study
This study is a double-blind, randomized, controlled intervention study aimed at exploring whether high-frequency transcranial alternating current stimulation (Hi-tACS) can improve cognitive impairment in patients with…
- Trial name
- NCT06231732
- Testing
- high-frequency transcranial alternating current stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Sir Run Run Shaw Hospital
Catheter Complications
A Study of Stimulant Medications Infusion Through Midline Catheters Based on Real-world Data
Based on the previous research, this study intends to explore the outcome of trans-MC infusion of stimulant drugs when the MC tip is located in the subclavian vein/chest wall segment axillary vein, especially to analyze the…
- Trial name
- NCT06454552
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Sir Run Run Shaw Hospital
Non-Small-Cell Lung Cancer
A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC
This study aims to evaluate the efficacy and safety of SBRT combined with Puterizumab immunotherapy for non-small cell lung cancer with pulmonary metastases, and to determine the correlation between MRD and treatment efficacy.
- Trial name
- NCT06434740
- Testing
- Stereotactic Body Radiation Therapy，SBRT, Puterizumab
- Volunteers
- 37 people
- Sponsor
- Sir Run Run Shaw Hospital
Thrombocytopenia, Radiotherapy Side Effect
Hetrombopag for the Thrombocytopenia Induced by Concurrent Chemoradiotherapy
Thrombocytopenia represents one of the main toxicities of concurrent chemoradiotherapy, which may necessitate chemotherapy dose reductions, dose delays, or discontinuation, and even compromise survival.
- Trial name
- NCT06433830
- Testing
- Hetrombopag Olamine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sir Run Run Shaw Hospital
Lung Function Decreased
Pulmonary Ventilation Heterogeneity Determined by EIT During PFT in Subjects With Normal One-second Rates
To evaluate the demographic characteristics of normal one-second rates population in patients with pulmonary function tests recommended by outpatient physicians.
- Trial name
- NCT06407986
- Testing
- pulmonary function test
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sir Run Run Shaw Hospital
Colon Cancer, Robotic Surgery
Effectiveness of Robotic Surgery for Right Colon Cancer
This study aims to explore through a multi-center, randomized controlled clinical study whether robot-assisted radical resection of right colon cancer is superior to laparoscopic surgery in terms of surgical quality and…
- Trial name
- NCT06421974
- Testing
- DaVinci si or xi system, laparoscopic radical resection
- Where
- China
- Volunteers
- 610 people
- Sponsor
- Sir Run Run Shaw Hospital
Colorectal Cancer
Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer
The goal of this randomized controlled trial is to investigate whether ctDNA methylation is a more precise indicator to guide postoperative adjuvant chemotherapy in stage Ill colorectal cancer.
- Trial name
- cmPAT (NCT06167967)
- Testing
- ctDNA methylation, standard treatment
- Where
- China
- Volunteers
- 990 people
- Sponsor
- Sir Run Run Shaw Hospital
COPD
Heterogeneity of Lung Ventilation Determined by EIT During PFT in Patients With PRISM
To evaluate the demographic characteristics of PRISm population in patients with pulmonary function tests recommended by outpatient physicians.
- Trial name
- NCT06199258
- Testing
- pulmonary function test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
Catheter Complications
Comparison of Clinical Outcomes of Mini Midline Catheters With Different Placement Sites: a Randomized Controlled Trial
Peripheral venous catheters are the most commonly used vascular access devices in healthcare today, including indwelling needles, mini-midline catheters, and medium-length venous catheters.
- Trial name
- NCT06106659
- Testing
- Mini Midline
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Colorectal Cancer
Early Detection and Risk Stratification of Colorectal Cancer Based on miRNA Platform
This is a prospective, observational cohort study to establish the minimal residual disease (MRD) model for predicting relapse risk and identifying disease recurrence in patients with colorectal adenocarcinoma based on the miRNA…
- Trial name
- NCT06351384
- Testing
- miRNA detection test
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Acute Pancreatitis
The Application of Thoracic Epidural Analgesia in Patients With Acute Pancreatitis
Acute pancreatitis (AP) is one of the most common diseases of the digestive system, with its incidence increasing year by year. 15%-25% of patients will develop severe acute pancreatitis (SAP), characterized by necrosis and…
- Trial name
- NCT06327230
- Testing
- Thoracic Epidural Analgesia
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sir Run Run Shaw Hospital
Colorectal Cancer
The Efficacy and Safety of Lcaritin Combined With Bevacizumab and FOLFIRI in Treatment of Liver Metastases From Colorectal Cancer
To evaluate the efficacy and safety of the combination regimen of Icaritin with bevacizumab + FOLFIRI in patients with liver metastases from advanced colorectal cancer.
- Trial name
- NCT06269445
- Testing
- Icaritin Combined With Bevacizumab and FOLFIRI
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sir Run Run Shaw Hospital
Mental Illness
Multimodal Psychotherapy Training for Chinese Medical Students
Providing evidence-based, well-designed psychotherapy teaching to train them to get a basic understanding of psychotherapy and to gain required skills for clinical practice would be fundamental to medical students, residency.
- Trial name
- NCT06258460
- Testing
- psychotherapy training program intervention, the wail-list control intervention
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Rectal Adenocarcinoma
The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma
To evaluate the efficacy, safety and organ retention rate of short-course radiation combined with Adebrelimab and CAPEOX neoadjuvant therapy in patients with MSS/pMMR ultra low rectal adenocarcinoma.
- Trial name
- NCT06266832
- Testing
- Adebrelimab, Oxaliplatin, Capecitabine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sir Run Run Shaw Hospital