Clinical trials: sponsored by St. Olavs Hospital
Abdominal Aneurysm, Thrombus
Vector Velocity Imaging in AAA Patients
The goal of this observational study is to perform an in vivo feasibility study using real time (3D) ultrasound based vector flow imaging in 10 AAA patients (5 with intraluminal thrombus and 5 without intraluminal thrombus).
- Trial name
- AAA-VFI (NCT05841524)
- Testing
- Vector flow imaging measurement
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- St. Olavs Hospital
Post-Concussion Syndrome, Post-Traumatic Headache
Acceptance and Commitment Therapy-based Rehabilitation of Post-concussion Symptoms
The investigators aim to evaluate effects of an outpatient rehabilitation program based on Acceptance and Commitment Therapy compared to usual care on function in patients with post-concussion syndrome (PCS) and post-traumatic…
- Trial name
- NCT04614922
- Testing
- Acceptance and Commitment Therapy
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- St. Olavs Hospital
Suicide Prevention, Suicide Threat
Psychoeducational Course for Suicide Prevention
The plan is to include patients with a history of increased risk of suicide. In the aftermath of an episode of imminent suicide risk, patients will receive a psychoeducational course that entails information on different aspects…
- Conditions
- Suicide Prevention, Suicide Threat, Self Efficacy, Stress, Psychological
- Trial name
- NCT06466356
- Testing
- Psychoeducational Course for Suicide Prevention, Individual therapy session, Treatment as usual
- Where
- 2 sites in Norway
- Volunteers
- 80 people
- Sponsor
- St. Olavs Hospital
Child Development, Gastrocnemius Equinus
Gastrocnemius Tightness and Foot Pain in Children
Foot and leg pain among otherwise healthy children is a common reason for referral to our pediatric orthopaedics outpatient clinic.
- Trial name
- NCT05862246
- Testing
- Clinical examination
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Meningioma
Embolization for Meningioma
The natural course for meningioma suggests that a majority will grow over time. Treatment is usually indicated in growing or symptomatic meningiomas.
- Trial name
- e-men (NCT05416567)
- Testing
- Endovascular embolization
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Mental Health Issue, Mental Disorder
Evaluation of a Digital Pre-therapy Patient Education Program (StartHjelp) in Outpatient Mental Health Care
Community mental health centers (CMHCs) face significant challenges in meeting the needs of individuals with mental health issues. For example, due to high demand, there are long waiting lists and low engagement rates.
- Conditions
- Mental Health Issue, Mental Disorder, Patient Education
- Trial name
- StartHjelp (NCT06212687)
- Testing
- Digital pre-therapy patient education program (StartHjelp), Comparator intervention
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- St. Olavs Hospital
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest
Double Sequential External Defibrillation (DSED) represents an alternative treatment of refractory ventricular fibrillation (rVF) in out-of-hospital cardiac arrest (OHCA).
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
- Trial name
- DUALDEFIB (NCT06672159)
- Testing
- Two defibrillators, One defibrillator
- Where
- Norway
- Volunteers
- 356 people
- Sponsor
- St. Olavs Hospital
Substance-Related Disorders, Drug Abuse
Structured Physical Exercise in Short-term Inpatient Treatment of Substance Use Disorder
In 2017, structured physical exercise with high intensity was implemented as a part of the treatment program at St. Olav Hospital Clinic of Substance Use and Addiction Medicine.
- Conditions
- Substance-Related Disorders, Drug Abuse, Drug Dependence
- Trial name
- NCT04141202
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Cerebral Palsy
Early Remote At-risk Diagnosis for Cerebral Palsy in Follow-up Clinics for High-risk Infants
Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age.
- Trial name
- In-Motion (NCT04287166)
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- St. Olavs Hospital
Pelvic Pain, Endometriosis
Pelvic Pain Electro-Acupuncture
The aim of the study is to investigate if a series of up to 9 treatment sessions of electroacupuncture can be used to alleviate pain in women with suspected endometriosis, scheduled for diagnostic laparoscopy
- Trial name
- PEARL (NCT07305025)
- Testing
- Electro acupuncture
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- St. Olavs Hospital
Pituitary Neoplasms, Adenoma
Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas
Due to lack of hormone overproduction in non-functioning pituitary adenomas (NFPAs), only the symptomatic adenomas or large adenomas with proven growth and risk for symptoms in near future will undergo pituitary surgery.
- Trial name
- NCT02288962
- Testing
- cabergoline
- Where
- 3 sites in Norway, Sweden
- Volunteers
- 60 people
- Sponsor
- St. Olavs Hospital
Knee Injuries
Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
In this randomized controlled trial the investigators will compare the results after primary anterior cruciate ligament (ACL) reconstruction using two different methods for femoral fixation of a bone-patellar tendon-bone (BPTB)…
- Trial name
- NCT02918734
- Testing
- Endobutton CL BTB, Metal interference screw
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Chronic Migraine
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- NCT06485336
- Testing
- Atorvastatin 40mg
- Where
- 6 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Obesity, Bariatric Surgery Candidate
Effect of Patient Education on Drinking Behaviour and Oral Hygiene in Patients Undergoing Bariatric Surgery
The background for the study is that many bariatric surgery patients struggle with their oral health after bariatric surgery. This is probably related to both physiological changes and changes in eating and drinking patterns.
- Trial name
- BAR-VANNTANN (NCT06617689)
- Testing
- Various levels of patient education
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- St. Olavs Hospital
Asthma, Inflammation
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing
The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus…
- Trial name
- INSTAR (NCT03889743)
- Testing
- Dexamethasone treatment during 3 days
- Where
- 8 sites in Finland, Norway and 1 more
- Volunteers
- 280 people
- Sponsor
- St. Olavs Hospital
Myeloma Multiple, Plasma Cell Leukemia
The Norwegian Immunotherapy in Multiple Myeloma Study
The goal of this observational study is to study the effectiveness and complications of novel immunotherapies used in the treatment of multiple myeloma in routine care in Norway.
- Conditions
- Myeloma Multiple, Plasma Cell Leukemia, AL Amyloidosis
- Trial name
- NIMMS (NCT06855121)
- Testing
- Teclistamab, Elranatamab, Ciltacabtagene Autoleucel
- Where
- 23 sites in Norway
- Volunteers
- 400 people
- Sponsor
- St. Olavs Hospital
Tumor, Colorectal, Organoids
Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1)
COSENSE-1 is an unblinded, phase II, single-armed, single center feasibility study for using a functional precision medicine platform to select oxaliplatin-based versus irinotecan-based chemotherapy regimens, for male and female…
- Conditions
- Tumor, Colorectal, Organoids, Tumoroid, Metastatic Colorectal Cancer
- Trial name
- COSENSE-1 (NCT06907342)
- Testing
- FOLFOX or FOLFIRI
- Where
- Norway
- Volunteers
- 148 people
- Sponsor
- St. Olavs Hospital
ADHD
The Effect of a Brief Educational Intervention for Adults With ADHD
This RCT-study proposes the evaluation of an intensive educational intervention tailored for adults with Attention Deficit Hyperactivity Disorder (ADHD) in community mental health centers (CMHCs).
- Trial name
- NCT06284655
- Testing
- group-based combined with innovative technology education, Standard treatment
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- St. Olavs Hospital
Neoplasms, Colorectal
Physically Active During Cancer Treatment (FAKT)
This randomized controlled trial aims to investigate whether an individually tailored exercise program and nutritional guide can affect the development of self-reported peripheral sensory neuropathy and fatigue in patients with…
- Trial name
- FAKT (NCT03885817)
- Testing
- Exercise training and nutritional guide, Standard follow-up care
- Where
- 5 sites in Norway
- Volunteers
- 66 people
- Sponsor
- St. Olavs Hospital
Insomnia Disorder, Circadian Rhythm Sleep Disorder
The Sleep Clinic Outcome and Practice Study
The goal of this clinical trial is to explore the outcome and practice treatment for sleep-wake disturbances in a Sleep Clinic. The main questions it aims to answer are: What is the practice (timing and duration of treatment…
- Trial name
- SUP (NCT06669507)
- Testing
- Chronotherapy, Cognitive Behavioral Therapy for Insomnia
- Where
- Norway
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital