Clinical trials: sponsored by St. Olavs Hospital
COVID-19, Pneumonia, Viral
Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection
In light of the ongoing COVID-19 epidemic in Norway, it is paramount to develop and utilize clinical tools for assessing and risk stratifying patients with suspected coronary infection in the emergency departments.
- Conditions
- COVID-19, Pneumonia, Viral, Pulmonary Infection
- Trial name
- COVIDUS-NOR (NCT04422691)
- Testing
- Lung ultrasound
- Where
- 9 sites in Norway
- Volunteers
- 5 people
- Sponsor
- St. Olavs Hospital
Breast Neoplasm
Adjuvant Endocrine Therapy in Early Stage Breast Cancer: Adherence and Clinical Outcome
Breast cancer is the most common cancer among women in Norway. In 2016, 3402 new cases were diagnosed (3371 in women). Breast cancer is still the second most common cause of death from cancer among women with 585 breast cancer…
- Trial name
- NCT03761420
- Where
- Norway
- Volunteers
- 1,411 people
- Sponsor
- St. Olavs Hospital
Coronary Disease
Diagnostic Accuracy of CT-FFR Compared to Invasive Coronar Angiography With Fractional Flow Reserve
Invasive coronary angiography is currently considered gold standard in the assessment of coronary artery disease although the method has limitations.
- Trial name
- NCT03045601
- Testing
- CT-FFR, Stress echocardiography
- Where
- Norway
- Volunteers
- 182 people
- Sponsor
- St. Olavs Hospital
Sarcoidosis, Cardiomyopathies
Diagnostic Potential of PET/MRI in Cardiac Sarcoidosis
The aim of the study is to find better and more specific non-invasive methods to diagnose and stage cardiac sarcoidosis with the use of advanced imaging modalities, simultaneous 3T MRI and PET.
- Trial name
- NCT03561025
- Testing
- 18F-FDG-PET/MRI, 18F-GE180-PET/MRI
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- St. Olavs Hospital
Pain, Postoperative, Postoperative Nausea and Vomiting
Efficacy Safety Score in Postoperative Management
The primary aim of this project is to determine whether postoperative patients may benefit from the Efficacy Safety Score (ESS) as a tool for postoperative clinical decision support, with a special focus on the first 24 hours…
- Trial name
- NCT03438578
- Testing
- Efficacy Safety Score monitoring
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Obesity
Feasibility Pilot for the ReBOO-trial
This is a pilot testing the feasibility of the 'REpurposing BOtulinum Toxin in Treatment of Obesity in Adolescents' trial (ReBOO-trial).
- Trial name
- ReBOO (NCT03079557)
- Testing
- Intragastric botulinum toxin type A
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- St. Olavs Hospital
Critical Illness, Septic Shock
Microcirculatory Alterations in Critical Disease: New Ultrasound Technology
Aim of this study is (1) to test and further develop a new non-invasive ultrasound method, and (2) to gain new insight into microcirculatory alterations during critical disease, particularly in critical septic shock patients.
- Trial name
- SepCease (NCT03311568)
- Testing
- ultrasound for microcirculatory assessment
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Femoral Neck Fractures
Effect of Local Infiltration Anesthesia With Ropivacaine on Postoperative Pain After Hip Hemiarthroplasty
At St.Olavs Hospital each year about 400 patients are treated for femoral neck fractures, 250 of them receiving hemiarthroplasty.
- Trial name
- NCT02585011
- Testing
- Ropivacaine, Epinephrine, Saline
- Where
- Norway
- Volunteers
- 123 people
- Sponsor
- St. Olavs Hospital
Insomnia
Cognitive Behavior Therapy for Insomnia Delivered by a Therapist or on the Internet
Background: Insomnia is a highly prevalent and disabling disorder where Cognitive Behavior Therapy for Insomnia (CBT-I) is established as the best available treatment.
- Trial name
- NCT02044263
- Testing
- Internet CBT-i SHUTi, face-to-face CBT-i
- Where
- Norway
- Volunteers
- 101 people
- Sponsor
- St. Olavs Hospital
Fatigue Syndrome, Chronic
Rehabilitation of Adolescents Living With Chronic Fatigue
Previous studies have shown that health-related quality of life (HRQoL) in adolescents living with chronic fatigue syndrome (CFS/ME) is low if compared with healthy adolescents and adolescents living with other chronic diseases.
- Trial name
- NCT04177459
- Testing
- Health promoting dialogue, standard treatment / treatment as usual
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- St. Olavs Hospital
Prostatic Hyperplasia, Hypertension
Does Benign Prostatic Obstruction Cause Hypertension?
The known correlation between benign prostatic hypertrophy (BPH) and hypertension could be explained by 3 theoretical pathway models.
- Trial name
- NCT02347436
- Testing
- 24-hr ambulatory blood pressure measurement
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Brain Injuries, Olfaction Disorders
Olfaction Disorders in Patients Included in The Trauma Brain Injury (TBI) Database at Trondheim University Hospital
The aim of the study is to see whether patients with chronic smell impairment after brain injury benefit from a treatment that consists of corticosteroids, and then olfactory training in 3 months.
- Trial name
- NCT02565121
- Testing
- corticosteroids, olfactory stimulation
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Postoperative Hemorrhage, Breast Neoplasms
The Effect of Topical Tranexamic Acid on Bleeding and Seroma Formation in After Undergoing Mastectomy
After surgical procedures, interventions to reduce postoperative bleeding are of great importance. In this study, the effect will be investigated of smearing tranexamic acid, which is designed for injection, directly onto the raw…
- Conditions
- Postoperative Hemorrhage, Breast Neoplasms, Seroma
- Trial name
- NCT02627560
- Testing
- Tranexamic Acid, saline
- Where
- 2 sites in Norway
- Volunteers
- 202 people
- Sponsor
- St. Olavs Hospital
People With Normal Sense of Smell
Does Olfactory Training Improve Olfaction in a Population With Normal Sense of Smell?
Awareness of the sense of smell in the western population has been low. Most people do not think about the consequences of absence of smell (anosmia). Reduction in sense of smell (hyposmia) can influence everyday life.
- Trial name
- NCT02980718
- Testing
- intensive olfactory training, ordinary olfactory training
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Evaluation of a Smartphone Based Optical Diagnostic Tool for Neonatal Jaundice
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT03007563
- Testing
- bilirubin concentration estimation from smartphone pictures, bilirubin concentration measured in standard blood samples, bilirubin concentration measured by transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 342 people
- Sponsor
- St. Olavs Hospital
Cluster Headache, Chronic Disease
Continuous Positive Airway Pressure as a Potential New Treatment for Cluster Headache
Cluster headache is also called suicide headache due to excruciating nocturnal attacks. There are few treatment options available. Inhalation of oxygen has shown to abort the attacks.
- Trial name
- CPAP (NCT03397563)
- Testing
- Continuous Positive Airway Pressure
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Cerebral Palsy
Smartphone App for Analysis of General Movements in Young Infants
Analysis of spontaneous movements in young infants from video recordings is recommended as an early medical assessment tool for prediction of cerebral palsy in high-risk infants.
- Trial name
- NCT03409978
- Testing
- in-Motion app
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 86 people
- Sponsor
- St. Olavs Hospital
Premature Birth
Reliability Testing of Silverman-Andersen Retraction Score in Preterm Infants
Depending on their gestational age, preterm infants need several weeks with different types of breathing-support due to immature development of the lungs, respiratory muscles, chest-wall and respiratory center in the brain.
- Trial name
- NCT03199898
- Testing
- Silverman-Andersen Retraction Score
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- St. Olavs Hospital
Osteoarthritis, Hip
Evaluation of a Short Femoral Stem in Total Hip Arthroplasty
In recent years, short femoral stems have been introduced. Short stems are designed based on traditional stems with good clinical results.
- Trial name
- NCT02743208
- Testing
- Short stem hip arthroplasty (SHA), Total hip arthroplasty (THA)
- Sponsor
- St. Olavs Hospital
Schizophrenia
Long-Term Exercise Training Therapy Versus Usual Care in Patients With Schizophrenia
Patients with schizophrenia have disabling symptoms and cognitive deficits that limit motivation, drive, social- and occupational performance, quality of life and self-efficacy.
- Trial name
- LEXUS (NCT02743143)
- Testing
- Exercise therapy, Follow-up care as usual
- Where
- Norway
- Volunteers
- 48 people
- Sponsor
- St. Olavs Hospital