Clinical trials: sponsored by St. Olavs Hospital
Spinal Stenosis, Spinal Cord Compression
Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis
Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis.
- Trial name
- NCT02006901
- Testing
- microdecompression, laminectomy
- Where
- Norway
- Volunteers
- 721 people
- Sponsor
- St. Olavs Hospital
Fracture
Subcapital and Shaft Fractures of the 5. Metacarpal
The purpose of this study is to find out the best treatment for subcapital and shaft fractures of the 5. metacarpal. It is a prospective randomized multicenter study. Comparing only fractures dislocated more than 30 degrees.
- Trial name
- NCT01242982
- Testing
- Closed reduction and fixation with 2 pins, Reduction and Plaster of Paris
- Where
- 5 sites in Norway
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Colles' Fracture
Dorsal Splint or Circular Cast for Colles' Fracture?
At our hospital, all Colles' fractures deemed suitable for conservative treatment are reduced and immobilised with a plaster of Paris dorsal splint which is converted to a complete cast after 10 days.
- Trial name
- NCT00470691
- Testing
- plaster cast, dorsal splint
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- St. Olavs Hospital
Acromegaly
Preoperative Octreotide Treatment of Acromegaly
The purpose of this study is to investigate whether 6 months preoperative treatment with the somatostatin analogue octreotide improves the surgical outcome in patients with acromegaly.
- Trial name
- POTA (NCT00521300)
- Testing
- Octreotide, Direct surgery for acromegaly
- Where
- 5 sites in Norway
- Volunteers
- 62 people
- Sponsor
- St. Olavs Hospital
Chronic Pain, Cancer
Nasal Fentanyl for Patient Controlled Treatment of Pain in Cancer
Traditionally cancer pain is treated with long acting opioids such as morphine around the clock. However, there is no evidence that all patients have a stable pain requiring around the clock medication.
- Trial name
- NFCP1-2010 (NCT01248611)
- Testing
- fentanyl
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- St. Olavs Hospital
Asthma
Sensitivity and Specificity of Aridol Challenge for a Diagnosis of Asthma by a Specialist Pulmonologist
The purpose of this study is to estimate the sensitivity, specificity and positive and negative predictive values of a positive Aridol challenge with respect to a specialist pulmonologist diagnosis of asthma in corticosteroid…
- Trial name
- NCT00491153
- Where
- 3 sites in Norway
- Volunteers
- 35 people
- Sponsor
- St. Olavs Hospital
Automobile Driving
Driving Simulator Performance After Intake of Zopiclone Sleeping Pills
Zopiclone, a widely used hypnotic drug, is frequently found in blood samples taken from drivers suspected of driving under the influence.
- Trial name
- NCT01257165
- Testing
- Zopiclone, Ethanol
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Purpura, Thrombotic Thrombocytopenic
Prophylactic Plasma Infusion Therapy for Congenital Thrombotic Thrombocytopenic Purpura
Congenital thrombotic thrombocytopenic purpura (TTP), also called Upshaw-Schulman Syndrome or hereditary or familial TTP is a rare, but severe disease.
- Trial name
- NCT01754545
- Sponsor
- St. Olavs Hospital
Hemorrhage
Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.
In this study we will investigate whether tranexamic acid given as an intravenous bolus injection before start of surgery, followed by a continuous infusion during surgery reduces, perioperative hemostatic activation, and…
- Trial name
- NCT00375466
- Testing
- Tranexamic acid
- Where
- Norway
- Volunteers
- 63 people
- Sponsor
- St. Olavs Hospital
Type 2 Diabetes
n-3 Fatty Acid Infusion and Type 2 Diabetes
The purpose of this experimental study is to investigate whether an acute lipid infusion added marine n-3 fatty acids produces effects on insulin sensitivity in subjects with type 2 diabetes, when compared with an acute lipid…
- Trial name
- NCT00829569
- Testing
- Intralipid +/- Omegaven
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- St. Olavs Hospital
Perinatal Morbidity
Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy
Post term pregnancy is a risk pregnancy. Aim of the study was to investigate whether induction of labor at gestational age 289(41 weeks+2 days) reduces neonatal morbidity compared to expectant management.
- Trial name
- NCT00385229
- Testing
- induction of labor
- Where
- Norway
- Volunteers
- 508 people
- Sponsor
- St. Olavs Hospital