Clinical trials: sponsored by Stanford University
Age-Related Macular Degeneration
Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension
The primary goal of the study is to test dietary intervention at glycemic control and carotenoid levels in participants with intermediate age-related macular degeneration.
- Trial name
- GLOVE (NCT07605468)
- Testing
- Low glycemic Mediterranean diet behavioral modification
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pilonidal Disease
Intraoperative Wound Irrigation for Pilonidal Disease
The purpose of this study is to determine the best method for cleaning wounds during surgery for patients with Stage 3 pilonidal disease.
- Trial name
- NCT07417202
- Testing
- Hypochlorous Acid
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Pre Diabetes, Insulin Resistance
Precision Diets for Diabetes Prevention
With this study the investigators want to understand the physiological differences for people developing pre-diabetes and diabetes.
- Conditions
- Pre Diabetes, Insulin Resistance, Diabetes Mellitus, Type 2
- Trial name
- NCT03919877
- Testing
- Dietary, Oral Food Challege
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pulmonary Arterial Hypertension (PAH)
Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)
The primary objective of this study is to compare the efficacy, safety, and tolerability of tiprelestat plus Standard of Care (SOC) compared with placebo plus SOC in patients with World Health Organization (WHO) functional class…
- Trial name
- ATHENA (NCT07601295)
- Testing
- Tiprelestat (5 mg), Tiprelestat (10 mg)
- Where
- 10 sites in United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Major Depressive Disorder
Opiate Suicide Study in Patients With Major Depression
To explore whether intravenous ketamine followed by buprenorphine produces more rapid and sustained anti-suicidal effects than ketamine followed by placebo, investigators will conduct a single study that will take approximately…
- Trial name
- AFSP (NCT04116528)
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Chronic Pain
Stanford Pragmatic Effectiveness Comparison
Chronic pain is a major healthcare problem with an annual cost of above $600 billion. The quality of data available for treatments of chronic pain is not optimal.
- Trial name
- SPEC-AA (NCT04441034)
- Testing
- Anti-convulsant medications, Anti-depressant medications
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder, Illness Anxiety Disorder
Study of Dextromethorphan in OCD and Related Disorders
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
- Conditions
- Obsessive-Compulsive Disorder, Illness Anxiety Disorder, Body Dysmorphic Disorders, Somatic Symptom Disorder
- Trial name
- NCT04899687
- Testing
- Fluoxetine, Dextromethorphan
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Pleomorphic Adenoma of the Parotid, Warthin Tumor
Identification of Nerves Using Fluorescein Sodium
The purpose of this study is to see if there is benefit in using an IV contrast (sodium fluorescein) to identify nerves during head and neck surgery.
- Conditions
- Pleomorphic Adenoma of the Parotid, Warthin Tumor, Head and Neck Disorder, Head and Neck
- Trial name
- NCT06054178
- Testing
- Fluorescein Sodium
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Alzheimer Disease, Mild Cognitive Impairment
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Recent findings suggest that sleep disruption may contribute to the generation and maintenance of neuropsychiatric symptoms including anxiety, depression, agitation, irritation, and apathy while treating sleep disruption reduces…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
- Trial name
- NCT04100057
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Desensitization Therapy for insomnia (DT-I)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Autism Spectrum Disorder, Autism
Online Pivotal Response Treatment Training in Autism Spectrum Disorder
This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD).
- Trial name
- PRT-O (NCT06523387)
- Testing
- Pivotal Response Treatment Online (PRT-O) Course
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain
IceBath: NOICE vs Nothing
This prospective, randomized, 2-period crossover study seeks to evaluate the effect of the non-visual immersive technology-based audio biofeedback intervention, delivered through devices such as NOICE device or Quest 3, on cold…
- Trial name
- NOICE-Icebath (NCT07227142)
- Testing
- Non-visual immersive technology-based audio biofeedback intervention, Control (No non-visual immersive technology-based audio biofeedback)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild Cognitive Impairment, Mild Dementia
Assessing Cognitive Decline at Home
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia
- Trial name
- NCT06704971
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer, Ovarian Cancer
Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples
The purpose of this study is to try to understand the biology of development of breast, ovarian, fallopian tube, peritoneal or endometrial cancer from persons at high genetic risk for these diseases.
- Conditions
- Breast Cancer, Ovarian Cancer, Gynecologic Cancers, Ovarian/Peritoneal/Fallopian Cancer
- Trial name
- NCT01034033
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- Stanford University
Melanoma, Brain Metastases
Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases
This is a multicenter, phase II trial of relatlimab (rela), nivolumab (nivo), and ipilimumab (ipi) in patients with asymptomatic and symptomatic melanoma brain metastases.
- Trial name
- NCT06712927
- Testing
- Ipilimumab, Nivolumab + Relatlimab FDC
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Gastric Cancer
The Gastric Cancer Foundation: A Gastric Cancer Registry
The Gastric Cancer Registry will combine data acquired directly from patients with gastric cancer; with a family history of gastric cancer in a first or second degree relative; or persons with a known germline mutation in their…
- Trial name
- NCT01514045
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05494398
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Depression - Major Depressive Disorder
Stratified Pharmacological Approaches for Regulating Circuit-Level Effects
This research study aims to understand how people with depression respond to the medication pramipexole and to determine whether clinical response differs depending on the function of specific circuits in the brain.
- Trial name
- SPARCLE (NCT07022405)
- Testing
- Pramipexole Immediate Release
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05664789
- Testing
- N acetyl cysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Virtual Reality, Bucket List
Assessing the Feasibility of Using Virtual Reality Experiences in Older Adults
To assess the feasibility of using computer-generated VR (CG-VR) and film-based VR (FB-VR) in seriously ill older adults
- Conditions
- Virtual Reality, Bucket List, Serious Illness, Aging
- Trial name
- NCT07580352
- Testing
- Feasibility of using VR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Stanford University
Pregnancy Complications, Mental Health Issue
Psychobiological Interventions in Pregnancy
This randomized control trial will evaluate whether a physical activity intervention can improve mental health and biologic markers of stress in pregnant people with depressive or anxiety symptoms.
- Conditions
- Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk
- Trial name
- PIP (NCT06430853)
- Testing
- Step count goal, Actigraph watch
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Stanford University
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