Clinical trials: sponsored by Stanford University
Liver Cirrhosis, Cirrhosis
Empagliflozin in Diuretic Refractory Ascites
Ascites is the most frequent complication of liver cirrhosis and results in increased morbidity and mortality but current medical management options are limited.
- Conditions
- Liver Cirrhosis, Cirrhosis, Ascites, Ascites Hepatic
- Trial name
- DRAin-Em 01 (NCT05013502)
- Testing
- Empagliflozin 10 MG
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
KRAS Gene Mutation, Metastatic Malignant Neoplasm in the Brain
Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
This phase II trial studies how well regorafenib works together with methotrexate in treating participants with metastatic non-squamous non-small cell lung cancer with tumors that harbor a KRAS mutation.
- Conditions
- KRAS Gene Mutation, Metastatic Malignant Neoplasm in the Brain, Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer AJCC v7
- Trial name
- NCT03520842
- Testing
- Methotrexate, Pharmacokinetic Study, Regorafenib
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Heart Failure
Mobile Technology-Based System for Patient Engagement and Physician-Directed Remote Management of Heart Failure
This pilot study is to assess the feasibility, preliminary utility and acceptance of a digital technology-based system for heart failure management.
- Trial name
- NCT05647317
- Testing
- A combination of a provider-facing desktop and mobile application with a patient-facing mobile application
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Pain, Postoperative, Anterior Cruciate Ligament Injury
Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions
Nerve blocks are used to provide pain control after moderately painful orthopedic surgeries. Anterior Cruciate Ligament (ACL) reconstruction with patellar autograft is a painful orthopedic procedure performed after traumatic…
- Trial name
- NCT03208478
- Testing
- Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Neuropathic Pain, Nociceptive Pain
PET/MRI in the Diagnosis of Chronic Pain
Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain.
- Conditions
- Neuropathic Pain, Nociceptive Pain, Mixed Pain (Nociceptive and Neuropathic), Spinal Pain
- Trial name
- NCT03556137
- Testing
- [18F]FTC-146
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Stanford University
Bipolar Disorder, Manic, Bipolar Disorder I
Accelerated Theta Burst Stimulation for Inpatients With Bipolar Disorder
This study evaluates the efficacy of an accelerated schedule of theta-burst stimulation for treating manic episodes in bipolar disorder. In this open-label study, all participants will receive accelerated theta-burst stimulation.
- Trial name
- NCT04058249
- Testing
- Accelerated intermittent theta-burst stimulation over right DLPFC
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Autistic Disorder, Developmental Disabilities
Evaluating Parent Delivered Interventions for Children With Autism
The investigators will assess the efficacy of parent delivered interventions in the treatment of social and communication deficits in children with autism.
- Trial name
- NCT01882153
- Testing
- Pivotal Response Training (PRT), PACE Therapy, PACE and PRT Hybrid
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Stanford University
Pregnancy Related, Influenza, Human
NK Cell Mediated Influenza Immunity During Pregnancy
Pregnant women have increased morbidity and mortality due to infection with influenza. Changes in T cell function have been proposed as possible mechanisms for this finding.
- Trial name
- Flu vaccine (NCT03196245)
- Testing
- There is no intervention.
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Stanford University
Epilepsy, Pregnancy
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)
Epilepsy is one of the most common neurological disorders affecting women of childbearing age. Poor pregnancy outcomes are increased in these women and their children.
- Trial name
- MONEAD (NCT01730170)
- Where
- 20 sites in United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- Stanford University
Liver Cancer, Liver Tumor
Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation
The purpose of this study is to prospectively analyze the value of 3D ultrasound perfusion imaging for treatment planning, the prediction of therapy success, and to monitor the treatment response in patients with a primary or…
- Conditions
- Liver Cancer, Liver Tumor, Hepatocellular Carcinoma, Liver Carcinoma
- Trial name
- NCT02424955
- Testing
- perflutren lipid microspheres, 3D ultrasound
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
Intraoperative Bleeding
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery
In endoscopic sinus surgery a clear surgical field of view is a very important aspect for good surgical outcome. This study is to evaluate the preoperative preparation to acquire best surgical field of view by comparing between…
- Trial name
- NCT05867342
- Testing
- Epinephrin, 1% lidocaine with epinephrin 1:100,000, Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
End of Life, Cancer
Lay Health Worker Engage, Educate, and Encourage Patients to Share
The purpose of the LEAPS program is to understand how a trained lay health worker who engages with newly diagnosed patients after a diagnosis of an advanced stage of cancer can help to engage patients in advance care planning…
- Trial name
- LEAPS (NCT03699748)
- Testing
- Lay Health Worker Intervention, Usual Care
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Stanford University
Covid19
COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol
The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization.
- Trial name
- COPPS (NCT04662073)
- Testing
- Camostat
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Stanford University
Covid19
COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Master Protocol
The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization.
- Trial name
- NCT04662086
- Testing
- Acebilustat, Camostat
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Stanford University
Kidney Transplant; Complications
Activity Therapy After Kidney Transplant
To combat post-transplant weight gain, we seek to expand Stanford Kidney Transplant's multidisciplinary platform to include physical activity monitoring and coaching using the Apple Watch.
- Trial name
- NCT03426280
- Testing
- Apple Watch Series 1
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Hidradenitis Suppurativa
Complement C5a Receptors in Hidradenitis Suppurativa
To study the role of C5a in Hidradenitis Suppurativa (HS). Complement C5a is a major chemotactic factor that stimulates neutrophil infiltration.
- Trial name
- NCT04251663
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Air Pollution, Pregnancy
Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution Exposure
The purpose of this project is to study the effects of air pollution toxicants on pregnant mothers' immune health during and after pregnancy.
- Trial name
- NCT04549142
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Stanford University
Covid19
COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Acebilustat Sub-Protocol
The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization.
- Trial name
- COPPS (NCT04662060)
- Testing
- Acebilustat
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Gastroesophageal Reflux, Patient Activation
Developing and Testing Mobile Health Question Prompt List in Gastroesophageal Reflux Disease
More than 40% of patients with gastroesophageal reflux disease (GERD) experience uncontrolled, chronic symptoms. This proposal aims to improve symptom control for patients with GERD, by developing a mobile health (mHealth)…
- Trial name
- NCT05900687
- Testing
- Use of mHealth Question Prompt List app
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Labor Onset and Length Abnormalities
Breath Metabolomics in the Laboring Parturient
This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible.
- Trial name
- NCT04564196
- Testing
- Breath Sample
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Stanford University
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