Clinical trials: sponsored by Tang-Du Hospital
Fertilization
Mechanical Stimulation Improve the Fertilization in ICSI Cycle
Most fertilization failures after ICSI are caused by failure of oocyte activation defects. But, to date, there is no effective method to overcome this obstacle.
- Trial name
- NCT03810001
- Testing
- Mechanical Stimulation
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Embryo Quality
Group Culture May Affect Embryo Quality in Assisted Reproduction Technology
One of the vital factors in achieving pregnancies in assisted reproductive technologies (ART) is maximizing embryo quality, which is significantly influenced by embryo culture conditions.
- Trial name
- NCT04011319
- Testing
- group culture
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Pregnancy Outcomes
Does LAH May Improve the Pregnancy Outcomes?
A defect in the hatching stage is considered an important cause of implantation failure. Therefore, assisted hatching (AH), which involves artificial disruption of the zona pellucida, has been proposed as a method for improving…
- Trial name
- NCT03810157
- Testing
- Laser-assisted hatching system
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Embryo
Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF
Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality.
- Trial name
- NCT03810040
- Testing
- 140 microns denuding pipette, 150 microns denuding pipette
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Non-small Cell Lung Cancer
Is Video-assisted Thoracoscopic Lobectomy a Clinical Alternative for Surgically Resectable Pathologic N2 NSCLC Patients
The study was designed to compare the safety and effectiveness of vedio-assisted thoracoscopic lobectomy with open lobectomy for patients with surgically resectable pathologic N2 non-small cell lung cancer
- Trial name
- NCT03613467
- Testing
- VATS lobectomy, Thoracotomy lobectomy
- Where
- 10 sites in China
- Volunteers
- 2,145 people
- Sponsor
- Tang-Du Hospital
Non-small Cell Lung Cancer
A Study to Explore Prognoses of the Patients With N2 Non-small Cell Lung Cancer
The trial was designed to compare the effectiveness of radical resections of lung cancer plus adjuvant chemotherapies and perioperative chemotherapies in the patients with N2 non-small cell lung cancer
- Trial name
- NCT03451526
- Testing
- Surgeries
- Where
- 10 sites in China
- Volunteers
- 2,929 people
- Sponsor
- Tang-Du Hospital
Chronic HIV Infections
Chidamide in Combination With ART for Reactivation of the Latent HIV-1 Reservoir
HIV replication can be effectively suppressed and acquired immunodeficiency syndrome(AIDS) can be prevented with highly active antiretroviral therapy (HAART).
- Trial name
- NCT02902185
- Testing
- ART plus Chidamide
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Non Small Cell Lung Cancer
A Study to Explore Prognoses of NSCLC Patients Complicated With Oligometastases
An observational study to explore prognoses and clinical treatments of the patients with non-small cell lung cancer complicated with oligometastases
- Trial name
- NCT03427541
- Testing
- Surgeries
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tang-Du Hospital
Non-small Cell Lung Cancer Metastatic
A Study to Evaluate Effectiveness and Safety of Tyrosine Kinase Inhibitors
This is a real-world non-interventional observational study. The study was designed to evaluate the effectiveness and safety of clinical treatments in the patients with advanced non-small cell lung cancer (NSCLC) complicated with…
- Trial name
- NCT03424980
- Testing
- Tyrosine kinase inhibitors
- Where
- 5 sites in China
- Volunteers
- 200 people
- Sponsor
- Tang-Du Hospital
Addiction
Deep Brain Stimulation of Nucleus Accumbens for Opioid Relapse Prevention
Nucleus accumbens plays important roles in the process of opiate addiction and initial of relapse after detoxification.According to the single-centered preliminary open-labeled prospective trial results, the investigators…
- Trial name
- NCT03424616
- Testing
- Suzhou Sceneray® DBS System
- Where
- 5 sites in China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Narcolepsy, REM Sleep Behavior Disorder
Investigation of Clinical Feature and Brain Function in Narcoleptic Patients
This study evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD
- Trial name
- NCT03376568
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Lung Cancer
Preventive Effects of Zoledronic Acid on Bone Metastasis in Patients With Stage IIIB and IV Lung Cancer
Bone metastases are common in patients with advanced lung cancer and can have devastating consequences. Preventing or delaying bone metastases may improve outcomes.
- Trial name
- NCT02622607
- Testing
- Zoledronic acid
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tang-Du Hospital
Thymic Epithelial Tumor
Preoperative Prediction of of Thymic Epithelial Tumors by Diffusion-Weighted MR Imaging
The aim of this study is to analyze aquaporins expression of thymic epithelial tumors and to compare them with apparent diffusion coefficient(ADC) from ultra-high b-values, and to test a possibility of use of ADCuh to identify…
- Trial name
- NCT03212027
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Healthy Volunteers
Optimal Low B-value in Intravoxel Incoherent Motion Diffusion-weighted MR Imaging of the Brain
Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
- Trial name
- NCT02411864
- Testing
- different low b-values distribution
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Aneurysm, Intracranial, Natural History
The Natural Course of Unruptured Intracranial Aneurysms in a Chinese Cohort
This is a registry study of the natural course of unruptured intracranial aneurysms (UIA). In addition, the investigators will analyze the risk factors for the rupture of the UIA and their joint effect.
- Trial name
- NCT03117803
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Tang-Du Hospital
Sweat Gland Diseases
A Minimally Invasive Surgery for Axillary Osmidrosis: Combined Liposuction With Subcutaneous Pruning
Patients with axillary osmidrosis are treated with minimally invasive procedure combined tumescent liposuction with Subcutaneous Pruning. Effectiveness of this modified method in reducing odor is to be determined.
- Trial name
- NCT01539460
- Testing
- minimally invasive surgery
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tang-Du Hospital
Subarachnoid Hemorrhage, Aneurysmal
Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage
Decompressive craniectomy has been reported for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH). But no prospective randomised controlled trials have yet been undertaken to confirm its effect.The purpose…
- Trial name
- NCT02995928
- Testing
- Decompressive craniectomy, Best medical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Glioma of Brain
Noninvasively Predicting Gene Status of Glioma
Malignant gliomas are the most common and deadly primary brain tumors in adults. The clinical outcome of patients with glioblastoma depends on key molecular genetic alteration.
- Trial name
- NPGSOG (NCT03102112)
- Testing
- MRI examination
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tang-Du Hospital
Subarachnoid Hemorrhage, Aneurysmal
Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage.
The purpose of this study is to evaluate the predictive value of serum adiponectin levels in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT02814162
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Menopause, Migraine
The Functional Magnetic Resonance Imaging Study on the Processing of Acute Pain and Cognition Among Perimenopause Women
There lacks effective early screen system for the migraine-susceptible women during the peri-menopause period. The processing of acute pain and cognition as well as the underling functional magnetic resonance imaging (fMRI)…
- Trial name
- NCT02820974
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital