Clinical trials: sponsored by Tanta University
Vitiligo Vulgaris, Microneedling-Assisted Delivery
Comparative Study of Topical Pentoxifylline Versus Topical 5-Fluorouracil Combined With Microneedling and NB-UVB for Stable Vitiligo
This randomized, single-blinded clinical trial evaluates the efficacy and safety of topical pentoxifylline compared with topical 5-fluorouracil, both combined with microneedling and narrow-band ultraviolet B (NB-UVB)…
- Conditions
- Vitiligo Vulgaris, Microneedling-Assisted Delivery, Phototherapy
- Trial name
- PTX-5FU-VIT (NCT07775105)
- Testing
- Microneedling + topical treatment (PTX 20 mg/ml) followed by NB phototherapy, Microneedling + topical treatment (5-FU 5%) followed by NB phototherapy, Microneedling alone followed by NB phototherapy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Tanta University
HCV Infection ( Genotype 4) in CKD Patients
Treatment of CKD Patients With HCV
The goal of this clinical trial is to evaluate the optimal drug therapy of HCV in CKD Patients different stages with or without compensated cirrhosis.
- Trial name
- HCV/CKD (NCT07770984)
- Testing
- SOF+DCV, OBV/PTV/r) ± ribavirin (RBV)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Nasal Packing Duration, One-Day Packing
Comparative Study of Nasal Packing Duration: One-Day Packing Versus Three-Day Packing After Turbinate Surgery
This study aimed to assess the optimum timing for nasal packs removal after turbinate surgery by comparing removal after one day versus removal after three days.
- Conditions
- Nasal Packing Duration, One-Day Packing, Three-Day Packing, Turbinate Surgery
- Trial name
- NCT07775118
- Testing
- Nasal packing for 1 day, Nasal packing for 3 days
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Androgenetic Alopecia, Exosomes
Exosome Injection Versus Topical Minoxidil for Androgenetic Alopecia
Androgenetic alopecia (AGA) is a common form of hair loss characterized by progressive hair follicle miniaturization. This prospective randomized comparative study evaluates the efficacy and safety of intradermal exosome…
- Trial name
- EXO-MINO (NCT07776015)
- Testing
- exosomes injection, Topical Minoxidil 5%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Intrathecal Morphine, Intrathecal Dexmedetomidine
Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries
This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.
- Conditions
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Placebo, Postoperative Pain
- Trial name
- NCT07777627
- Testing
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Acute Kidney Injury, Obesity
Effect of Gabapentin on Kidney Function Following Laparoscopic Sleeve Gastrectomy (LSG)
This study evaluated the effect of a single preoperative dose of gabapentin on renal stress and kidney function following laparoscopic sleeve gastrectomy in adults with severe obesity.
- Trial name
- NCT06254183
- Testing
- Laparoscopic Sleeve Gastrectomy, gabapentin 1200 mg
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Depression
Allopurinol in Depression
Major depressive disorder (MDD) is one of the most common psychiatric disorders with serious socioeconomic consequences on daily life and health care costs.
- Trial name
- NCT07574060
- Testing
- Sertraline 50 MG, Allopurinol 300 MG
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Biliary Disease
Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP (, a key tool that is used in diagnosis and treatment of pancreato-biliary diseases.
- Trial name
- NCT06860984
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Severely Resorbed Mandibular Ridge in Completely Edentulous Patients
Comparison of Three Final Impression Techniques for Severely Resorbed Mandibular Ridges
This in vivo crossover study aims to compare the accuracy of three different final impression techniques for severely resorbed mandibular ridges in completely edentulous patients.
- Trial name
- NCT07764640
- Testing
- Conventional final impression, Wax impression technique, Compound impression technique
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Tanta University
Conventional Static Surgical Guide, SocketFit Static Surgical Guide
Evaluation the Accuracy of Immediate Implant Placement Using SocketFit Static Surgical Guide Versus Conventional Static Surgical Guide in Anterior Esthetic Zone
This study compares two types of surgical guides used during immediate dental implant placement in the upper front teeth. One guide is a conventional static surgical guide, while the other is a modified SocketFit static surgical…
- Trial name
- SocketFit (NCT07760974)
- Testing
- SocketFit Static Surgical Guide, Conventional Static Surgical Guide
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tanta University
Dental Caries, Composite Resins
Clinical Evaluation of Dentin Replacement Materials in Posterior Composite Restorations
This randomized controlled clinical trial is designed to clinically evaluate and compare the performance of five dentin replacement materials used beneath posterior composite restorations.
- Conditions
- Dental Caries, Composite Resins, Composite Restoration
- Trial name
- NCT07762651
- Testing
- Biodentine, ACTIVA BioACTIVE, glass ionomer cement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Diabetes Mellitus, Type 2
Effect of Nicorandil in Type 2 Diabetic Obese Patients
1. Evaluating the effect of nicorandil on glycemic control of diabetic obese patients treated with sulfonylureas. 2. Investigating the effect of nicorandil on body weight of diabetic obese patients treated with sulfonylureas.
- Trial name
- NCT06423729
- Testing
- Nicorandil 10 MG
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Tanta University
Post Operative Pain After Pediatric Hip Surgery
Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery
Surgical repair of the hip can be extremely painful and is associated with considerable postoperative pain in children despite the use of systemic opioids.
- Trial name
- NCT04336085
- Testing
- caudal block, pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Cirrhosis, Hepatic Encephalopathy
Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis
The study aims to compare the potential benefit of allopurinol versus atorvastatin in reducing the risk of developing cirrhosis-related complications, delaying the onset of hepatocellular carcinoma, and improving survival.
- Conditions
- Cirrhosis, Hepatic Encephalopathy, Ascites, Varices
- Trial name
- NCT05511766
- Testing
- Allopurinol 300 MG, Atorvastatin 20mg
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Microneedling-Assisted Delivery, Cetirizine
Microneedling-Assisted Delivery of Cetirizine Versus Latanoprost in Alopecia Areata
This study planned to measure the effectiveness and safety of microneedling aided administration of cetirizine 1% versus latanoprost 0.01% in alopecia areata.
- Conditions
- Microneedling-Assisted Delivery, Cetirizine, Latanoprost, Alopecia Areata
- Trial name
- NCT07757867
- Testing
- Cetirizine (Zyrtec), Latanoprost, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Knee Osteoarthritis
Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.
- Trial name
- NCT07664371
- Testing
- Cryoneurolysis, pulsed radiofrequency (RF), cooled radiofrequency
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Hair Transplantation
Fractional CO₂ Laser Before Follicular Unit Extraction Hair Transplantation With Platelet-Rich Plasma for Secondary Cicatricial Alopecia
Secondary cicatricial alopecia is characterized by permanent hair loss due to destruction of hair follicles following trauma, burns, infection, or other causes.
- Trial name
- CO2-FUE-PRP (NCT07751523)
- Testing
- hair transplantation preceded by fractional and PRP
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Acanthosis Nigricans
Systemic and Topical Metformin Versus Glycolic Acid Peel for the Treatment of Acanthosis Nigricans
Acanthosis nigricans (AN) is a common dermatologic condition associated with insulin resistance and obesity. Existing treatment options often provide inconsistent results.
- Trial name
- MET-AN (NCT07751549)
- Testing
- systemic metformin, topical intervention, glycolic acid 70% peeling
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Nosocomial Infection
Bilirubin Increases the Risk of Nosocomial Infection in Cirrhotic Patients
Nosocomial infection (NIs) is a major challenge in healthcare facilities and has been associated with prolonged hospital stay as well as increased morbidity and mortality.
- Trial name
- {bilirubin} (NCT05752084)
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Tanta University
Major Depressive Disorder (MDD), Female
Gottman Couple Therapy Program in Treatment of Depressed Female Partners
This study aimed to evaluate the effect of Gottman couple therapy program targeted for discordant couples struggling with the negative impact of depression of the female partner and compare between the outcome in case of usual…
- Trial name
- NCT07748845
- Testing
- Gottman couple therapy, treatment as usual for depression
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University