Clinical trials: sponsored by Technical University of Munich
Breast Neoplasm Female, Radiotherapy Side Effect
Gated Radiotherapy in Left Sided Breast Cancer Patients
To assess the need of respiratory gated radiotherapy in left sided breast cancer patients.
- Conditions
- Breast Neoplasm Female, Radiotherapy Side Effect, Heart Diseases
- Trial name
- GATTUM (NCT03534570)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
Schizophrenia, Schizo-affective Disorder
A Shared Decision-making Training for Inpatients With Schizophrenia
"Shared decision-making" is being promoted as a promising approach for engaging patients with schizophrenia in medical decisions and improving satisfaction and adherence.
- Trial name
- NCT02349880
- Testing
- shared decision making training
- Volunteers
- 264 people
- Sponsor
- Technical University of Munich
Diabetes Mellitus, Type 1
Pre-POINT-Early Study
Type 1 diabetes (T1D) results from an autoimmune destruction of the insulin-producing beta cells within the pancreatic islets of Langerhans.
- Trial name
- NCT02547519
- Testing
- Oral Insulin
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Prenatal Stress
Fetal Biomarkers of Chronic Maternal Stress During Pregnancy
The investigators´ main hypothesis is that prenatal stress (PS)- induced programming during fetal and postnatal development is reflected in epigenetic and autonomic nervous system (ANS) biomarkers which can be harnessed for early…
- Trial name
- FELICITy (NCT03389178)
- Testing
- Cohen Perceived Stress Scale-10 (PSS-10)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
Colorectal Cancer
Tertiary Prevention by Exercise in Colorectal Cancer Therapy
The purpose of this study is to determine the feasibility of a one year exercise training program in post-surgical patients with colorectal cancer.
- Trial name
- F-PROTECT (NCT01991847)
- Testing
- Physical activity
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Post-ERCP Acute Pancreatitis
Post-ERCP Pancreatitis Prevention by Stent Insertion
The presented study is designed to analyze the efficacy of pancreatic stent insertion in patients undergoing ERCP with accidental cannulation of the pancreatic duct.
- Trial name
- PEPSI (NCT01673763)
- Testing
- Stent insertion into the main pancreatic duct
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 169 people
- Sponsor
- Technical University of Munich
Obesity, Cardiovascular Risk
School Based Health Promotion Program in Secondary Schools
The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.
- Trial name
- JuvenTUM 3 (NCT00988754)
- Testing
- School children and adolescents as health experts
- Where
- Germany
- Volunteers
- 595 people
- Sponsor
- Technical University of Munich
Comparing the Number of Surgical Site Infections, Covering of the Abdominal Wall in Laparotomies With an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven
Covering of the Abdominal Wall in Laparotomies: Differences in Surgical Site Infections Between an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven Swabs at Technische Universität München
BaFo is a prospective, double-blinded randomized controlled clinical trial that assesses the numbers of surgical site infections in two different techniques of covering the abdominal wall in laparotomies.
- Conditions
- Comparing the Number of Surgical Site Infections, Covering of the Abdominal Wall in Laparotomies With an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven, Swabs
- Trial name
- BaFo (NCT01181206)
- Testing
- Intervention Arm 1: Covering with approved abdominal 3M™ Steri-Drape™ Wound Edge Protector Intervention Arm 2: Covering with standard woven swabs
- Where
- Germany
- Volunteers
- 516 people
- Sponsor
- Technical University of Munich
Distal Humerus Fracture
Polyaxial Locking Plates in Treating Distal Humeral Fractures
20 patients with distal humeral fractures (AO 13-A1 - AO 13-C3) were included in the current study since 2014. After completing the randomization plan, patients were distributed into two groups for different variable angle…
- Trial name
- NCT03272490
- Testing
- Medartis, Synthes
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Cardiovascular Diseases, End Stage Renal Disease
Modulation of Inflammation by Medium Cut Off Membranes
This study examines whether medium-cut off dialysis results in improved blood purification of large middle molecules e.g. inflammatory molecules compared to hemodialysis (HD) treatments with conventional high-flux dialyzers.
- Trial name
- MCO-IF (NCT03270371)
- Testing
- Medium cut off dialysis, Standard High Flux Dialyzer
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Insulin Resistance
Changes in Insulin Sensitivity in Healthy Volunteers Taking Tenofovir Alafenamide (TAF)-Containing Antiretroviral Medication
Investigation of possible changes in insulin sensitivity in healthy volunteers taking the following HIV treatment combinations: F/TAF (group 1) as compared to E/C/F/TAF (group 2) as compared to R/F/TAF (group 3).
- Trial name
- TAF-IR (NCT03092206)
- Testing
- F/TAF, E/C/F/TAF, R/F/TAF
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Duodenal Papilla, Major
Cap Assisted Forward-Viewing Endoscope vs Side-Viewing Endoscope for Examination of Major Duodenal Papilla
Examination of major duodenal papilla (MDP) using a standard forward-viewing esophagogastroduodenoscopy (S-EGD) is limited. Until now, side-viewing duodenoscope is the modality of choice to examine the MDP.
- Trial name
- KappaII (NCT02883608)
- Testing
- cap assisted forward-viewing endoscope
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Endoscopic Diagnosis in Esophagus
The Diagnostic Yield of Cap Assisted Upper Endoscopy in Esophagus
Cap assisted colonoscopy, a simple technique of fixing a transparent plastic cap to the tip of the colonoscope, was proven to increase the adenoma detection rate during screening colonoscopy by helping to depress and flatten…
- Trial name
- Kappa-III (NCT02883621)
- Testing
- cap assisted upper endoscopy, standard upper endoscopy
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Diagnosis Prosthetic Joint Infection
Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection
The two-stage protocol is gold standard in terms of infection control treating prosthetic joint infections of total hip and total knee arthroplasty.
- Trial name
- SyPJI (NCT03038464)
- Testing
- Synovial biopsy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Survival, Prostheses
Evaluation of Partial and Total Femoral Replacement
Several surgical options for the reconstruction of massive bone defects have been described and include biologic methods with autografts and allografts, and the use of tumor endoprostheses (total femoral replacement, TFR).
- Trial name
- EFeRe (NCT03045536)
- Testing
- MML (Fa. ESKA/Orthodynamics)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Colon Cancer
Short Message Service in Colonoscopy Preparation (PERICLES-II-SMS)
The purpose of this study is to analyze if integration of new media (SMS) could improve the quality of colonoscopy preparation.
- Trial name
- PERICLES-II (NCT02272036)
- Testing
- Colonoscopy, mobile phone
- Where
- 4 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Renal Cell Carcinoma
Phase III Sequential Open-label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Pazopanib Versus Pazopanib Followed by Sorafenib in the Treatment of Advanced / Metastatic Renal Cell Carcinoma (SWITCH-II)
Sorafenib and pazopanib are both effective and promising treatments for advanced Renal Cell Carcinoma (RCC). Both drugs are registered for this indication.
- Trial name
- NCT01613846
- Testing
- Sorafenib+Pazopanib, Pazopanib+Sorafenib
- Where
- 72 sites in Austria, Germany and 1 more
- Volunteers
- 544 people
- Sponsor
- Technical University of Munich
Colon Adenoma
Side Specific Withdrawal Times for Colonoscopy: Impact on Adenoma Detection in the Proximal and Distal Colon
Adenoma detection in the main goal of screening colonoscopy. In order to detect adenomas it is mandatory to spend a long enough time investigating the colonic mucosa.
- Trial name
- SNOWCAT (NCT02819492)
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Colonic Polyps
Acetic Acid for Optical Characterization of Colonic Polyps
Adenomas and hyperplastic polyps are polypoid lesions that can occur in any part of the colon. Currently all polyps should be resected endoscopically, however adenomas have the potential to develop into colorectal cancer whereas…
- Trial name
- ATOMIC I (NCT02760381)
- Testing
- NBI + Acetic Acid (AA)
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Technical University of Munich
Colon Adenoma
Computer-assisted Detection of Colonic Polyps
Screening colonoscopy is considered the gold standard for adenoma detection in the colon. However, it has been shown that a considerable number of polyps can be missed during screening colonoscopy.
- Trial name
- KoloPol I (NCT02838888)
- Testing
- Automatic polyp detection software
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich