Clinical trials: sponsored by Technical University of Munich
Hypoxemia, Complications
Capnography During ERCP
In the study the value of capnography for avoiding complications during sedation for ERCP is evaluated.
- Trial name
- EndoBreath (NCT01072474)
- Testing
- Capnography, Standard monitoring
- Where
- 3 sites in Germany
- Volunteers
- 242 people
- Sponsor
- Technical University of Munich
Cholangiocarcinoma
Gemcitabine/Oxaliplatin and Photodynamic Therapy in Cholangiocarcinoma
In patients with cholangiocarcinoma therapeutic effects have been reported for Gemcitabine/Oxaliplatin. Furthermore, photodynamic therapy (PDT) has significantly improved patients survival in two randomised trials.
- Trial name
- GemOx-PDT (NCT00713687)
- Testing
- Gemcitabine, Oxaliplatin, Photodynamic therapy (Photosan®)
- Where
- Germany
- Sponsor
- Technical University of Munich
Acute Myeloid Leukemia
Combination of Nilotinib (AMN107) and RAD001 in Patients With Acute Myeloid Leukemia
This is a nonrandomized, open-label study to evaluate the efficacy and safety of combination treatment of Nilotinib and RAD001 in the treatment of c-kit + AML.
- Trial name
- NCT00762632
- Testing
- NILOTINIB, EVEROLIMUS
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Breast Cancer
Chemotherapy and Hormone Therapy as First-Line Therapy in Treating Postmenopausal Women With Metastatic or Locally Advanced Breast Cancer
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Estrogen can cause the growth of breast cancer cells.
- Trial name
- NCT00403182
- Testing
- chemotherapy, letrozole
- Where
- 9 sites in Germany
- Sponsor
- Technical University of Munich
Apnea, Hypoxemia
Capnography During Percutaneous Transhepatic Cholangiodrainage (PTCD) (HepaBreath)
Capnography provides noninvasive monitoring of ventilation and can allow early recognition of altered respiration patterns and apnea.
- Conditions
- Apnea, Hypoxemia, Complications
- Trial name
- NCT01587157
- Testing
- capnography
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Gastric Subepitelial Mass
Endoscopic Resection of Gastric Subepithelial Masses, EndoResect Study
Gastric subepithelial masses might harbour gastrointestinal stromal tumors, which should get resected because of their malignant potential. To minimize the associated surgical trauma endoscopic endoluminal resection is favorable.
- Trial name
- EndoResect (NCT01105728)
- Testing
- Endoscopic resection
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Technical University of Munich
Gastrointestinal Stromal Tumor
Imatinib Mesylate in Treating Patients With Locally Advanced Gastrointestinal Stromal Tumor
RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving imatinib mesylate before surgery may shrink the tumor so that it can be removed.
- Trial name
- NCT00112632
- Testing
- imatinib mesylate, conventional surgery, neoadjuvant therapy
- Where
- 9 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Stroke, Dementia
Prevention of Stroke and Dementia in Primary Care
In Western Countries, stroke and dementia are the main causes of long-term disability, dependency, and nursing home admission. Due to demographic trends a continuous increase of patient numbers can be expected.
- Conditions
- Stroke, Dementia, Disability
- Trial name
- INVADE (NCT01107548)
- Testing
- Systematic detection of vascular risk factors and subsequent evidence-based treatment
- Where
- Germany
- Volunteers
- 3,908 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Bladder Cancer
Tumorspecific T-cell Immunity in Bladder Cancer as Prognostic Marker
Bladder cancer is generally susceptible to immunotherapeutic measures. The investigators will characterize 40 patients with muscle-invasive bladder cancer regarding the existence and frequency of tumorspecific T-cells and…
- Trial name
- NCT01198808
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Atopic Dermatitis, Atopic Eczema
Atopic Dermatitis Biomarker Identification Trial in Omalizumab Usage
This study aims at evaluating the therapeutic potential of omalizumab in atopic dermatitis, and to work out biomarkers predictive of treatment response.
- Trial name
- AMB-WEI-1052-I (NCT01179529)
- Testing
- Omalizumab (Xolair®)
- Where
- Germany
- Sponsor
- Technical University of Munich
Angioedema
AMelioration of Angiotensin Converting Enzyme Inhibitor Induced Angioedema Study
This is a multicenter study recruiting patients with angioedema induced by ACEI. Open-label treatment with subcutaneous Icatibant compared to a historic group of 47 patients with ACE inhibitor induced angioedema which the…
- Trial name
- NCT01154361
- Testing
- Icatibant (subcutaneous) and plazebo (intravenous), Cortisone + Clemastin (intravenous) and plazebo (subcutaneous)
- Where
- Germany
- Sponsor
- Technical University of Munich
Cognitively Normal Elderly Individuals
Prevention of Postoperative Delirium With Donepezil
Patients undergoing hip or knee joint replacement at the age of 70 years or above who are cognitively unimpaired will receive donepezil or matching placebo before (over 5-7 days), during and after (over 7 days) surgery.
- Trial name
- NCT00220896
- Testing
- Donepezil
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- Technical University of Munich
Depression
Enhancing the Therapeutic Efficacy of Sleep Deprivation by Modafinil
The study aims to investigate whether the administration of the stimulant modafinil during a 40 hour sleep deprivation period in depressed patients can intensify the antidepressant effect of the sleep deprivation as assessed by a…
- Trial name
- NCT00670813
- Testing
- Modafinil (Vigil)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Sleep
Effect of Quetiapine XR on Sleep in Patients With Major Depression, as Compared With Mirtazapine
The purpose of this study is to examine the effects of (a) quetiapine XR and (b) mirtazapine on sleep when given as an antidepressant (monotherapy).
- Trial name
- NCT00782405
- Testing
- quetiapine, mirtazapine
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Depression
A Question Prompt Sheet for Depressive Outpatients
question prompt sheet for outpatients suffering from depression. effects on patient-doctor-communication during the consultation.
- Trial name
- NCT01313013
- Testing
- question prompt sheet
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Hypoxemia, Complications
Capnography During Colonoscopy
In the study the value of capnography for avoiding complications during sedation for colonoscopy is evaluated.
- Trial name
- ColoCap (NCT01072487)
- Testing
- Capnography
- Where
- 3 sites in Germany
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Decline in Renal Function
Aortic Stiffness in Chronic Kidney Disease Stage 2 to 4
This study aimed to investigate in a cohort with chronic kidney disease the longitudinal relationship between aortic stiffness and renal function and mortality.
- Trial name
- NCT01279460
- Where
- 2 sites in Germany
- Volunteers
- 167 people
- Sponsor
- Technical University of Munich
Dementia
Cognitive Behavioural Therapy of Early Dementia
A randomized, controlled, parallel-group trial to evaluate the efficacy of a cognitive behavioral therapy for patients with early dementia.
- Trial name
- KORDIAL (NCT00735046)
- Testing
- Cognitive behavioral therapy for early Alzheimer's disease, Control
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Osteoarthritis
Intra-articular Hyaluronic Acid in Mild to Moderate Knee Osteoarthritis
Objective: To assess the impact of intraarticular hyaluronic acid (HA) on clinical outcome and on volumetric and T2 relaxation based changes of articular cartilage in mild to moderate osteoarthritis (OA) of the knee joint.
- Trial name
- Ostenil (NCT01239810)
- Testing
- Hyaluronic Acid
- Volunteers
- 34 people
- Sponsor
- Technical University of Munich
Breast Cancer
Docetaxel, Epirubicin, and Cyclophosphamide With or Without Trastuzumab in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy, such as docetaxel, epirubicin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00398489
- Testing
- trastuzumab, anastrozole, cyclophosphamide
- Where
- 5 sites in Germany
- Volunteers
- 94 people
- Sponsor
- Technical University of Munich