Clinical trials: sponsored by Technical University of Munich
Nummular Eczema
Study of Dupilumab to Demonstrate Efficacy in Subjects With Nummular Eczema
Nummular eczema (NE) is an idiopathic chronic inflammatory skin disease that occurs throughout all life periods. Diagnosis is made primarily clinically in correlation with histological findings. Treatment of NE is difficult.
- Trial name
- DUPINUM (NCT04600362)
- Testing
- Experimental: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Technical University of Munich
Knee Osteoarthristis, Arthroplasty Replacement, Knee
Return to Sports After Knee Arthroplasty
The ability to return to sports after joint arthroplasty is increasingly becoming an important factor for patients in terms of their perceived quality of life.
- Trial name
- RTS (NCT07183475)
- Testing
- Return to sports test
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich
Critical Care, Rehabilitation
Prospective Registry of Mobilization-, Routine- and Outcome Data of Intensive Care Patients
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
- Conditions
- Critical Care, Rehabilitation, Outcome Assessment (Health Care)
- Trial name
- MOBDB (NCT03666286)
- Where
- Germany
- Volunteers
- 1,172 people
- Sponsor
- Technical University of Munich
Participants of the Be-MaGIC-Study 2009
Prospective Follow-up, Marathon, Long Term, Inflammation and Cardiovascular System
Pro-MagIC is a prospective observational study and includes participants of the Be-MaGIC-Study 2009 (n=277/NCT00933218). We aim to detect exercise-induced physiological changes (inter alia of the cardiovascular system) induced by…
- Trial name
- Pro-MagIC (NCT04166903)
- Where
- Germany
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Elbow Tendinopathy, Elbow, Tennis
Blood Flow Restriction Training For The Treatment Of Lateral Epicondylopathy
The study aims to evaluate the effectiveness of Blood Flow Restriction Training for the treatment of lateral elbow epicondylopathy.
- Conditions
- Elbow Tendinopathy, Elbow, Tennis, Lateral Epicondylitis, Epicondylitis of the Elbow
- Trial name
- EPIC-BFR (NCT07172568)
- Testing
- Blood Flow Restriction
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Nephrolithiasis, Lithotripsy, Laser
Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone Removal
The incidence of kidney stones (urolithiasis) has surged in both developing and developed countries, affecting approximately 15% of the global population.
- Conditions
- Nephrolithiasis, Lithotripsy, Laser, Ureteroscopy
- Trial name
- NCT06469736
- Testing
- Standard of Care Ureterorenoscopy, Standard of Care Ureterorenoscopy with MediNiK
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich
Major Depression Moderate, Major Depression Severe
Virtual Reality-Augmented At-Home tDCS for Major Depression
The goal of this clinical trial is to investigate the efficacy of combining Virtual Reality (VR)-based relaxation and Transcranial Direct Current Stimulation (tDCS) for treating Major Depression.
- Trial name
- VR-TMD (NCT07146269)
- Testing
- tDCS, VR-based relaxation therapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Cancer, Breast
Exercise in Triple- Negative Breast Cancer
This is a prospective, randomized, controlled mono-center study investigating the effects of a combined, supervised aerobic exercise and resistance training in female patients with newly diagnosed, therapy-naive triple-negative…
- Trial name
- ExACT-ICI (NCT06672120)
- Testing
- Exercise training
- Where
- 2 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich
Negative Symptoms in Schizophrenia, Schizophrenia Disorders
40 Hz Visual Stimulation as an Intervention in Schizophrenia
In schizophrenia, an abnormal reduction in neuronal gamma oscillations (30-100 Hz) is associated with negative symptoms such as cognitive dysfunction.
- Conditions
- Negative Symptoms in Schizophrenia, Schizophrenia Disorders, Schizoaffective Disorder
- Trial name
- GammaSZ (NCT06907420)
- Testing
- Visual stimulation
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Breathing Exercises
Relaxation Effects of Personalized Breathing Exercises for Healthy College Students
Stress plays a major role in the etiology and pathogenesis of anxiety and depression. Relaxation therapies, such as breathing exercises, can reduce stress and increase relaxation. This study has two aims.
- Trial name
- NCT06121596
- Testing
- Breathing Exercise
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Biochemical Recurrence of Malignant Neoplasm of Prostate
A Prospective, Bicentric Evaluation of Fluciclovine PET-imaging in Patients with Prior Negative or Inconclusive PSMA-ligand PET
The REFINE study is evaluating whether a fluciclovine (18F) PET/CT scan can detect recurrent prostate cancer in patients whose previous PSMA PET/CT was negative or inconclusive.
- Trial name
- REFINE (NCT06859203)
- Where
- 2 sites in Germany
- Volunteers
- 94 people
- Sponsor
- Technical University of Munich
Retrospective Study
Predicting Outcomes of Breast-Conserving Surgery in Breast Cancer Patients Using the Modified 5-Item Frailty Index
Background: Breast cancer is the most common malignancy among women worldwide, with breast-conserving surgery (BCS) being a key treatment.
- Trial name
- NCT06770647
- Where
- Germany
- Volunteers
- 96,586 people
- Sponsor
- Technical University of Munich
ME/CFS, CFS/ME
Multi-Center Registry for ME/CFS
The ME/CFS study (MECFS-R) aims to create a large-scale registry that provides data on epidemiology, phenotypes, and disease trajectories of and health care for ME/CFS at any age in Germany, which can be used for future clinical…
- Conditions
- ME/CFS, CFS/ME, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19
- Trial name
- MECFS-R (NCT05778006)
- Where
- Germany
- Volunteers
- 650 people
- Sponsor
- Technical University of Munich
Schizophrenia, Schizoaffective Disorder
A Shared Decision Making Training for Inpatients With Schizophrenia
Patients suffering from schizophrenia who attend the communication skills program engage more deeply in therapeutic reasoning and treatment decisions.
- Trial name
- NCT00885716
- Testing
- patient training in shared decision making, cognitive training
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Technical University of Munich
Eosinophilic Esophagitis
New Serological Markers for Eosinophilic Esophagitis
The purpose of the study is to investigate if serological parameters such as "extracellular Serum-Tryptase (ST)" and "eosinophilic cationic protein (ECP)" are useful for the diagnosis and surveillance of the eosinophilic…
- Trial name
- NCT01624129
- Testing
- Fluticasone
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Cardiovascular Prevention, Healthy
Connect2Move: Valorization of Natural Cardio Trekking Hiking Trails
Regular exercise improves performance and reduces the risk of cardiovascular disease. Endurance and strength training are therefore forms of therapy with a high level of evidence in the prevention and rehabilitation of…
- Conditions
- Cardiovascular Prevention, Healthy, Healthy Lifestyle
- Trial name
- Connect2Move (NCT05226806)
- Testing
- Measurement of cardiorespiratory performance in 3 different settings, GENERAL CARDIO HIKES AS PART OF GENERAL TOURIST OFFER OF MUNICIPALITIES
- Where
- Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Fabry Disease, Endothelial Dysfunction
Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study
This study aims to gain a deeper understanding of endothelial dysfunction in patients with Fabry disease through a prospective study of the retinal microvasculature and to identify an objective, non-invasive marker to assess…
- Conditions
- Fabry Disease, Endothelial Dysfunction, Microvasculature
- Trial name
- VASCinFABRY (NCT06758648)
- Testing
- Dynamic retinal vessel analysis (DVA), Biochemistry and immune phenotyping, Questionnaires (Patient reported outcomes)
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Technical University of Munich
Ischemic Stroke, Cryptogenic, Transient Ischemic Attack
Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke
Scientific Background: In secondary prevention of ischemic stroke, detection of atrial fibrillation (AFib) and subsequent anticoagulation therapy reduce the risk of recurrent stroke by approximately 60%.
- Conditions
- Ischemic Stroke, Cryptogenic, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- WATCH AFib (NCT06005233)
- Testing
- Smartwatch
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Technical University of Munich
Obesity
Personalized Nutrition and eHealth: Lifestyle Intervention (LION) Study for Weight Loss Maintenance
Despite standardized intervention strategies, weight loss and weight loss maintenance largely differ from person to person. Factors which may contribute to these individual differences is current object of research.
- Trial name
- LION (NCT04023942)
- Testing
- Weight maintenance intervention
- Where
- Germany
- Volunteers
- 272 people
- Sponsor
- Technical University of Munich
Telemedicine
Covid-19 Predictors: Safety of Gynecological Oncology Patients Undergoing Systemic Cancer Therapy
We designed a monocenter prospective cohort study using PROM via app and remote monitoring via pho-toplethysmography (PPG). The application of these technologies enables an early detection of infections and therefore initiation…
- Trial name
- CO-SI-ONKO (NCT05043220)
- Testing
- PPG and PROM
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich