Clinical trials: sponsored by Tel-Aviv Sourasky Medical Center
Cancer, Early Detection of Cancer
CancerenD24 Screening as an Aid to the Clinician for the Diagnosis of Cancer
The purpose of the researchers is to test whether the CancerenD24 index, an algorithm based on the quantitative value of CD24, CD11b, clinical and laboratory characteristics, developed in the laboratory can help in the early…
- Trial name
- CancerenD24 (NCT06656728)
- Testing
- Blood-based liquid biopsy
- Where
- Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Women, Age ≥45
Data Analysis to Evaluate Which Specific Gait Measures Are Associated with Risk of Injurious Falls Evaluating Gait Measures Associated with the Risk of Injurious Falls Through Data Analysis
The goal of this study is to understand if specific gait and activity measures can help predict injurious falls in older women. The main questions it aims to answer are: Can combining daily gait (DLG) and daily physical activity…
- Conditions
- Women, Age ≥45, After Menopause or Without Intention of Pregnancy
- Trial name
- WHS (NCT06644859)
- Testing
- Daily Activity Patterns Using Wearable Tri-Axial Sensors
- Where
- Israel
- Volunteers
- 17,466 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Type 1 Diabetes (T1D)
Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System
This is a pilot study to compare premeal to postmeal dosing of ultra rapid lispro insulin (URLi) used in a MiniMed 780G system hybrid closed loop system.
- Trial name
- NCT06600776
- Testing
- Ultra Rapid Lispro (URLi), Insulin pump with continuous glucose monitoring (CGM)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Motoric Cognitive Risk Syndrome
Home Transcranial Direct-Current Stimulation for Motoric Cognitive Risk Syndrome
1. To examine the effect of a two-week tDCS intervention of 3 months of continued tDCS intervention versus 3 months of receiving a placebo treatment (dummy).
- Trial name
- HometDCS (NCT06581458)
- Testing
- tDCS
- Volunteers
- 64 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Steps Against the Burden of Parkinson's Disease - StepuP
The goals of our StepuP project are: 1. To understand the kinematic and neural mechanisms underlying walking improvements due to treadmill training with and without VR-enabled gait adaptations in people with PD; 2.
- Trial name
- StepuP (NCT06538909)
- Testing
- VR
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
West Nile Virus, West Nile Fever Encephalitis
Early Interferon-beta Treatment for West-Nile Virus Infection
West Nile virus (WNV) is a mosquito-borne virus which in majority of cases causes only self-limited disease. Despite that, in minority of cases (~0.5%) it can infect the brain and cause severe and even life-threatening disease…
- Conditions
- West Nile Virus, West Nile Fever Encephalitis, West Nile Fever Myelitis, West Nile Fever With Other Complications
- Trial name
- NCT06510426
- Testing
- Rebif 44 MCG Per 0.5 ML Prefilled Syringe, Saline
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Helicobacter Pylori Infection
Auto Fecal Microbial Transplant Post Helicobacter Pylori Antibiotic Therapy
Current guidelines mandate Helicobacter pylori (H. Pylori) eradication with 2-3 antibiotics for 14 days ,This may result in multiple side effects and in eradication of important bacterial species to human health, exposing humans…
- Trial name
- NCT05329636
- Testing
- Fecal Microbial Transplant (FMT), Auto Fecal Microbial Transplant (FMT) via enema
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
PTSD
Resilience Among Trauma Survivors
A major gap remains in understanding the neurobehavioral mechanism of individuals' variability in the dynamic process of responding to traumatic events.
- Trial name
- NCT06484803
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Crohn Disease, Ulcerative Colitis
Inflammatory Bowel Diseases Remission Registry
The inflammatory bowel diseases (IBDs), ulcerative colitis (UC) and Crohn's disease (CD), are characterized by lifelong relapsing-remitting gastrointestinal inflammation, with symptoms of abdominal pain, diarrhea, and rectal…
- Conditions
- Crohn Disease, Ulcerative Colitis, Pouchitis
- Trial name
- NCT04912999
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Tic Disorders
XTics - A Gamified Enhancer of Non-Pharmacological Interventions in Tic Disorders
The investigators developed a neuroscientifically-informed gamified tic-therapy platform. The investigators previously identified tic-triggering elements in movies and video games.
- Trial name
- NCT06348511
- Testing
- XTics
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Fibromyalgia (FM)
Targeted Limbic Self-modulation as a Potential Treatment for Patients Suffering From Fibromyalgia
The goal of this study is to test whether voluntary regulation of limbic system activation is possible in patients with fibromyalgia and to examine the neurobehavioral effects of specific neuromodulation of this circuit on…
- Trial name
- NCT02146495
- Testing
- Simultaneous EEG and fMRI recordings, Amygdala-Electrical Fingerprint (Amyg-EFP)-NF Trial
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain
Paracetamol / Ibuprofen for Postpartum Pain in the Early Postpartum Period
The investigators will examine the effectiveness of non-opioid analgesia (Paracetamol versus Ibuprofen) in the early postpartum period
- Trial name
- NCT04653506
- Testing
- Paracetamol 1000 mg, Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Parkinson Disease
Digital Wearable Walking Aid for Freezing of Gait in Parkinson´s Disease
The objective of this study is to investigate the effects of relatively long-term use of a wearable device that provides personalized and intelligent cues (e.g. only when FOG is detected) on FOG.
- Trial name
- NCT03978507
- Testing
- Intelligent cueing, Feedback about the number of steps
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 62 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Metabolic Syndrome
Metabolically Healthy Obese
Little is known about the associated factors and mechanisms involved in the development of metabolic disturbance in pediatric obesity.
- Trial name
- MHO (NCT06032312)
- Testing
- description
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Post-stroke Depression
Safety of Maraviroc for Post-stroke Depression
Post-stroke depression (PSD) is a barrier to effective rehabilitation and recovery after stroke. Current treatment options are limited and there is an unmet need for specific and effective therapeutic options.
- Trial name
- MRV-PSD (NCT05932550)
- Testing
- Maraviroc 300 mg
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Indolent Lymphoma
Effect of Vegan Diet and Lifestyle Changes on Indolent Lymphoma During Controlled Waiting Period
The aim of the present trial is to evaluate the effect of lifestyle changes on the natural history of indolent lymphomas, during the period of watchful waiting.
- Trial name
- NCT04957693
- Testing
- vegan diet and lifestyle changes
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Delivery; Neuraxial Opioids
Respiratory Rate After Cesarean Delivery
The study proposal summarizes aspects related to respiratory rate in women who undergo spinal anesthesia for cesarean delivery who receive or do not receive neuraxial opioids
- Trial name
- NCT04250233
- Testing
- Respiratory Monitor
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postoperative Pain
Role of Opioids in Epidural Solutions
It is unclear whether addition of opioids to epidural solutions for postoperative analgesia is beneficial. In this multicenter randomized double-blinded trial, we aim to test the primary hypothesis that epidural solutions…
- Trial name
- NCT04251962
- Testing
- Bupivacaine, Fentanyl
- Where
- Israel
- Volunteers
- 135 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Urinary Catheter, Laparoscopic Surgery
Validation of Serenno CUO and IAP Measuring Device
Serenno Medical Automatic Urine Output measuring device is intended to measure volumetric flow rate (total volume and rate) of urine produced per minute over long periods by a patient with a urinary catheter as well as high…
- Trial name
- NCT05121454
- Testing
- Serenno Sentinel, model Alpha 2.0, software version: 8.0
- Where
- Israel
- Volunteers
- 31 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spontaneous Abortion, Missed Abortion
Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion
Randomizedtrial comparing success and complication rates of operative hysteroscopy versus traditional dilation and curettage (D\&C) in the management of first trimester missed abortion.
- Conditions
- Spontaneous Abortion, Missed Abortion, Intrauterine Adhesion, Retained Products of Conception
- Trial name
- NCT04705324
- Testing
- Operative Hysteroscopy, D&C, Operative Hysteroscopy - safety and feasibility
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center