Clinical trials: sponsored by The Hong Kong Polytechnic University
Chronic Low-back Pain (cLBP), Non-specific Low Back Pain (NSLBP)
Hybrid mHealth for Low Back Pain
The goal of this clinical trial is to evaluate whether adding a WhatsApp-based AI chatbot to standard physiotherapy and psychological care can improve self-management and outcomes in adults aged 18-65 with chronic low back pain…
- Trial name
- NCT07902778
- Testing
- Face-to-face physiotherapy and psychological care (for hybrid arm), WhatsApp-based AI chatbot for self-management (for hybrid and WhatsApp-only arms), Face-to-face physiotherapy and psychological care (No Digital Support) (for control arm)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
ADHD or ADHD Traits
Development and Evaluation of a Digital Game Intervention Targeting Children Vulnerable to ADHD
The goal of this clinical trial is to learn whether a self-administered digital game can improve attention, memory, and planning and reduce ADHD-like symptoms in children aged 6-12 in Hong Kong who have subclinical or vulnerable…
- Trial name
- NCT07900048
- Testing
- Digital Game Intervention, Tetris
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Neurogenic Overactive Bladder
Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With Stroke
Neurogenic overactive bladder (nOAB) is a common and distressing sequela following stroke, significantly impairing quality of life and imposing a substantial financial burden.
- Trial name
- NCT07768137
- Testing
- Active transcranial direct current stimulation (tDCS), Pelvic floor muscle training (PFMT)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Psychological Wellness
Resilient Students Training (ReST) : A Pilot RCT
Resilience is the ability to survive and thrive despite significant adversity. Trials of resilience-promoting interventions for university students have shown significant improvements in students' resilience and reductions in…
- Trial name
- ReST (NCT06157931)
- Testing
- Resilient Student Training intervention (ReST)
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
PARKINSON DISEASE (Disorder)
Oculomotor-Pupillary AI Biomarkers in Parkinson's
The goal of this prospective observational study is to investigate whether oculomotor-pupillary abnormalities detected using a novel edge-AI eye-tracking device can serve as objective and quantitative biomarkers for the early…
- Trial name
- NCT07886450
- Testing
- Edge-AI Eye-Tracking Assessment
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Stroke
Effects of Transcutaneous Electrical Nerve Stimulation on Cognitive Function and Upper Limb Motor Function in People With Chronic Stroke
Upper limb impairment is present in more than 85% of people with stroke, which greatly affect the quality of life, social participation, and performance of daily activities of people with stroke.
- Trial name
- NCT05615610
- Testing
- tSCS, tVNS, Control
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
acuTENS, Sleep Quality
Acu-TENS to Improve the Sleep Quality in People With Stroke
Post-stroke sleep disorder and motor/cognitive dysfunction are common complications that affect the quality of life of older patients.
- Conditions
- acuTENS, Sleep Quality, Stroke
- Trial name
- NCT05623137
- Testing
- Acu-TENS, SHP
- Where
- 2 sites in Hong Kong
- Volunteers
- 70 people
- Sponsor
- The Hong Kong Polytechnic University
Chemotherapy-induced Neuropathy
Home-Based Exercise and Vagus Nerve Stimulation for Chemotherapy-Induced Neuropathy
Background: Studies highlight the potential benefits of home-based exercise for cancer survivors with chemotherapy-induced neuropathy (CIN); however, its effectiveness in alleviating CIN-related sensorimotor impairments and…
- Trial name
- CIN (NCT07877558)
- Testing
- Active non-invasive vagus nerve stimulation (nVNS), Home-based aerobic and resistance exercise program
- Where
- 3 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Knee Osteoarthritis
Chatbot-based Pain Management for People With Knee Osteoarthritis
Knee osteoarthritis (OA) is a prevalent degenerative joint disease that causes chronic pain, stiffness, impaired physical function, and associated psychosocial issues such as depression, insomnia, and loneliness.
- Trial name
- C-MPPM (NCT07843784)
- Testing
- The C-MPPM intervention, Online education
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Mirror Therapy With Cutaneous Electrical Sensory Stimulation on Lower Limb Motor Functions in Stroke
This study aims to evaluate the effectiveness of concurrent mirror therapy (MT) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people with stroke.
- Trial name
- NCT03622879
- Testing
- MT, TENS, Lower-limb task-oriented training
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Upper Limb Mirror Therapy With Bilateral Transcutaneous Electrical Nerve Stimulation to Improve Upper Limb Functions in Patients With Stroke
This study compare the effectiveness of 2 rehabilitation programmes that use (1) MT with Bilateral TENS (Bi-TENS), (2) sham-MT with Bi-TENS (Bi-TENS), respectively, in addition to conventional rehabilitation of standardized upper…
- Trial name
- NCT03631628
- Testing
- Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS), Mirror Therapy (MT), Conventional Rehabilitation Program
- Where
- 2 sites in Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Cortical Excitability
Dual-task Training Combined With tDCS on Cognitive-motor Performance and Brain Activity in Stroke Patients
This study aims to evaluate the effects of tDCS combined with cognitive-motor training on dual-task interference during walking and foot pedaling, alongside corresponding alterations in brain activity assessed via fNIRS.
- Trial name
- dual-task tDCS (NCT06769672)
- Testing
- active tDCS with dual-task training
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Stroke
Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke
Stroke often impairs lower limb control, resulting in gait abnormalities and difficulties in dual-task performance, such as walking while engaging in cognitive activities.
- Trial name
- NCT06818240
- Testing
- Active transcranial direct current stimulation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Effect of a Multidimensional Intervention Programme on Post-stroke Fatigue
This study aims to evaluate the effects of a multidimensional intervention programme on fatigue and related outcomes among people with stroke.
- Trial name
- NCT07041138
- Testing
- cognitive behavioural programme with physical training, health education with physical training, Usual Care
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Motor Function
Effects of Home-based CIMT and Clinic-based CIM on Stroke
Constraint induced movement therapy (CIMT) is based on the theoretical basis that constraining the unaffected limb following injury of the brain such as stroke can help overcome learned non-use.
- Trial name
- NCT06465251
- Testing
- Home-based CIMT, Clinic-based CIMT, Control
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The Hong Kong Polytechnic University
Advanced Cancer, Demoralization
A Feasibility Study of a Digitally-enabled Psychological Intervention for Demoralization in Advanced Cancer Patients
Advanced cancer is a leading cause of death worldwide and in China. Cancer patients often face reduced independence and self-care abilities, which may lead to psychological disturbances such as helplessness, hopelessness, or…
- Conditions
- Advanced Cancer, Demoralization, Psychological Intervention
- Trial name
- NCT07872254
- Testing
- A digitally-enabled positive psychological intervention for demoralization in advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Sacropenic Obesity
Effects of the EatWelLog App on Enhancing Diet Management for Older Adults With Sarcopenic Obesity
Background: Sarcopenic obesity (SO) affects 10% of older adults increased to 23% of those 75+, raising health risks and health cost.
- Trial name
- NCT07867795
- Testing
- Dietary Modification programme, Exercise Training, The EatWelLog App
- Where
- Hong Kong
- Volunteers
- 212 people
- Sponsor
- The Hong Kong Polytechnic University
Nutritional Deterioration, Malignant Solid Tumor
Benefits of Nutritional Supplement in Cancer Care
This is an exploratory, open-label, 2:1 randomized controlled trial conducted across collaborating oncology clinics and extended research networks in Hong Kong.
- Conditions
- Nutritional Deterioration, Malignant Solid Tumor, Cancer Cachexia, Cancer Malnutrition
- Trial name
- NCT07869290
- Testing
- Nutrition supplement, Digital Health App Monitoring, Individualized Dietitian Consultation
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy Subjects (HS)
Reactive Balance Training in Augmented Reality for Older Adults
This is a single-blinded study. The participants will be equally randomized to either the reactive balance training with augmented reality (RBT+AR) group or the control (treadmill walking) group.
- Trial name
- NCT07860619
- Testing
- Reactive balance training with augmented reality group, Treadmill walking
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Parkinson s Disease
Effects of Mental Imagery With Self-regulation on Daily Activities in People With Parkinson's Disease
The goal of this clinical trial is to learn whether mental imagery combined with self-regulation can improve daily activities in people with Parkinson's disease.
- Trial name
- MI-SeR (NCT07860294)
- Testing
- Mental imagery with self-regulation, Exercise and health education
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University