Clinical trials: sponsored by The Hong Kong Polytechnic University
Spinal Cord Injuries (SCI), Depression
Evaluation of a Home-based AOMI Intervention on Cognitive Function and Depression Among Adults With SCI
The investigators propose a pilot randomized clinical trial to determine if adults with spinal cord injury (SCI) show improved cognitive function and depression following home-based Action Observation and Motor Imagery (AOMI)…
- Conditions
- Spinal Cord Injuries (SCI), Depression, Motor Imagery, Cognitive Functions
- Trial name
- NCT06708026
- Testing
- Action Observation and Motor Imagery (AOMI) training, Basic wheelchair exercises, Watch landscape videos
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Rotator Cuff Related Shoulder Pain
Effects of Movement Representation Techniques With Sensorimotor Training for Rotator Cuff Related Shoulder Pain
The aim of this study is to evaluate the efficacy of 12 weeks of sensorimotor training with movement representation techniques for reducing pain intensity in people with rotator cuff related shoulder pain, relative to standard…
- Trial name
- NCT06823206
- Testing
- Sensorimotor training with movement representation techniques
- Where
- Hong Kong
- Volunteers
- 122 people
- Sponsor
- The Hong Kong Polytechnic University
Choroid Disease, Caregiver
Dyadic Management Intervention in Older People With Co-occurring Cognitive Impairment and Diabetes as a Supplementary Approach to Chronic Diseases Self-Management Program
The goal of this study is to evaluate the effectiveness and implementation of a dyadic management of the Chronic Disease Self-Management Program (CDSMP) for older adults with co-occurring cognitive impairment and diabetes with…
- Conditions
- Choroid Disease, Caregiver, Self-management, Diabetes
- Trial name
- NCT07496359
- Testing
- CDSMP + caregiver support, Usual Care
- Where
- Hong Kong
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue
This study aims to evaluate the effect of transcranial direct current stimulation and cognitive behavioural programme on fatigue and its related outcomes among people with stroke.
- Trial name
- NCT06810817
- Testing
- tDCS & cognitive behavioral programme with home-based physical training, physical training
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- The Hong Kong Polytechnic University
Depression
Accelerated iTBS for Depression: Monitoring Brain Hemodynamics With Simultaneous iTBS/fNIRS
This study will investigate the cortical hemodynamic response variability of an accelerated form of TBS stimulation over left dorsolateral prefrontal cortex (DLPFC) using a concurrent TBS/fNIRS setup.
- Trial name
- NCT06971549
- Testing
- Accelerated iTBS
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- The Hong Kong Polytechnic University
Diabetes, Self-Control
Just-In-Time Adaptive Interventions for Diabetic Patients
The addition of proactive nurse consultations was useful to older adults with diabetes mellitus in facilitating their chronic disease self-management. However, the service is time and resource-intensive.
- Conditions
- Diabetes, Self-Control, Telemedicine
- Trial name
- NCT06466837
- Testing
- Just-in-time intervention, Active control
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The Hong Kong Polytechnic University
Postpartum Depression (PPD)
A Mobile Application for Early Detection and Symptoms Trajectories of Postpartum Depression Using Ecological Momentary Assessment (EMA)
This pilot study will recruit 120 perinatal pregnant women and follow them up for 6 months. Both momentary and retrospective assessments of emotional well-being and psychosocial factors will be conducted on a mobile application.
- Trial name
- EMA For PND (NCT07382336)
- Testing
- Ecological momentary assessment and retrospective assessment
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control
The purpose of the study is to investigate the combination effect of optical defocus and low dose atropine on myopia control in schoolchildren.
- Trial name
- NCT06358755
- Testing
- Defocus Incorporated Multiple Segments lenses, single vision spectacle lenses, Low dose atropine
- Where
- Hong Kong
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Symptom Cluster, Breathlessness
Mindfulness-Oriented Respiratory Distress Symptom Intervention for Lung Cancer
Lung cancer is the leading cause of cancer mortality, posing a critical public health challenge in both Hong Kong and global populations.
- Conditions
- Symptom Cluster, Breathlessness, Coughing, Fatigue Symptom
- Trial name
- NCT07281300
- Testing
- Mindfulness-Oriented Respiratory Distress Symptom Intervention (M-RDSI), Usual Care
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Brain Activity Changes After Structured Cognitive-motor Exercise for People With Stroke
To assess the effects of a dual-task exercise program on cognitive-motor interference during dual-task walking and the associated changes in brain activity.
- Trial name
- NCT06129227
- Testing
- Dual-task training, Single-task training, Control group
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- The Hong Kong Polytechnic University
Child With Cancer, Muscular Atrophy
Nurse Parental Support Using a Mobile App in Symptom Management for CMC
Parents of children with medical complexity (CMC) are suffering from high level of stress. These CMC get multisystem diseases, including severe neurologic conditions or cancer, resulting in potential premature death.
- Conditions
- Child With Cancer, Muscular Atrophy, Child With Cerebral Palsy, Child With Medical Complexity
- Trial name
- NCT05765643
- Testing
- Nurse parental support in symptom management using a mobile health App
- Where
- 2 sites in Hong Kong
- Volunteers
- 96 people
- Sponsor
- The Hong Kong Polytechnic University
Mood Disorders
Mindful Yoga for Postpartum Depression
This is a parallel-group randomized controlled trial. A total of 198 postpartum women with depressive symptoms (EPDS scores≥8 at baseline) will be recruited and randomized into two groups: 10-week mindful yoga intervention and…
- Trial name
- NCT06275217
- Testing
- Mindfulness-based yoga program, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy Lifestyle
A Pilot Randomized Controlled Trial of Chatbot Use in Older Adults for Lifestyle Change
The purpose of this study is to evaluate the acceptability and preliminary effectiveness of a smartphone-delivered AI-based chatbot in promoting healthy dietary behavior and physical activity participation among older adults.
- Trial name
- NCT06901037
- Testing
- A chatbot-based intervention
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Healthy Adults
Cross-validating the iTBS-induced Hemodynamic Response From fNIRS and fMRI: a Concurrent iTBS-fMRI-fNIRS Study
Intermittent theta-burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) is well established in treating patients with major depressive disorder (MDD).
- Trial name
- NCT06902571
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mental Health Help-seeking
Mental Health Help-seeking Promotion in Older Adults
The present study aims to examine the effectiveness of descriptive social norm nudges and pictorial social norm nudges in improving mental health help-seeking intention compared to educational information.
- Trial name
- NCT06707935
- Testing
- Descriptive social norm nudges, Pictorial social norm nudges, Service as usual
- Where
- Hong Kong
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dry Eye Disease (DED), Dry Eye
Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease
In this study, the initial tear proteome profiles in Dry Eye Disease (DED) patients, the safety and effectiveness of using an EC certificate DED treatment device in DED management, together with the associated global tear…
- Trial name
- NCT07175909
- Testing
- The Rexon-Eye, an electrotherapy device utilizing Quantum Molecular Resonance (QMR) technology
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- The Hong Kong Polytechnic University
Acceptance and Commitment Therapy, Child With Medical Complexity
Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity
A pilot randomized controlled trial of an Acceptance and Commitment Therapy-based intervention will be conducted to decrease psychological symptoms, while increase psychological flexibility for parents of a child with medical…
- Conditions
- Acceptance and Commitment Therapy, Child With Medical Complexity, Psychological Flexibility, Randomised Controlled Trial
- Trial name
- NCT07033832
- Testing
- ACT-based intervention
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Older Adults Without Any Specific Clinical Condition
Using Mölkky for Community-dwelling Older Adults
Physical activity is known to be a protector against major diseases. However, they usually do closed-skilled types, like jogging, swimming, Tai Chi.
- Trial name
- NCT07025967
- Testing
- Mölkky, Home activity
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Colour Perception, Color Perception
Visual Perception, Binocular Rivalry, and Fatigue-Related Individual Differences in Colour and Illumination Judgement
This observational study aims to characterise individual differences in colour perception and binocular rivalry. Participants will complete computer-based visual perception tasks, including a colour perception task and a…
- Conditions
- Colour Perception, Color Perception, Binocular Rivalry
- Trial name
- NCT07671144
- Testing
- Computer-Based Visual Perception Tasks
- Where
- 2 sites in Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Severe Mobility Impairment, Spinal Cord Injuries (SCI)
Effects of Virtual Walking on Chronic Pain and Psychological Distress for Individuals With Severe Mobility Impairment
This randomized controlled trial aims to: (1) examine the effects of virtual walking intervention on chronic pain (primary outcome), and on depression, stress, anxiety, and quality of life (secondary outcomes) compared with the…
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (SCI), Poliomyelitis
- Trial name
- NCT07820618
- Testing
- Virtaul walking, Passive observing video
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University