Clinical trials: sponsored by The Hong Kong Polytechnic University
Healthy Subjects (HS)
Self-initiated Perturbation-based Training in Older Adults
This is a single-blinded study. Participants will be randomly assigned to self-initiated perturbation-based balance training (SePBT) group or control (conventional balance training) group.
- Trial name
- NCT06774833
- Testing
- Self-initiated perturbation-based balance training, Conventional balance training
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia, Psychosis
Tele-group Cognitive Behavioural Family Intervention for People With Schizophrenia and Their Families (Feasibility tgCBFI)
This mixed-method study aims to examine the feasibility of delivering tgCBFI programme to dyads of people with schizophrenia and their family caregivers, and generate preliminary evidence on the effectiveness of tgCBFI in…
- Trial name
- NCT05808244
- Testing
- tgCBFI, Usual psychiatric care
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia and Related Disorders
Tele-group Cognitive Behavioural Family Intervention for Individuals With Schizophrenia and Their Families (Definitive tgCBFI)
This mixed-method study comprises a RCT with a twelve-week post-intervention follow-up and focus group interviews. The RCT study aims to examine the effectiveness of delivering the tgCBFI programme to dyads of people with…
- Trial name
- NCT07121166
- Testing
- tgCBFI programme, Treatment as Usual (TAU)
- Where
- 6 sites in Hong Kong
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Dietary Supplement for Myopia Control
The purpose of this clinical trial is to investigate the changes in choroidal thickness and vasculature in myopic children following oral supplementation.
- Trial name
- NCT07406906
- Testing
- Oral dietary supplement provided in a capsule format (3 active capsules/ per day)
- Where
- Hong Kong
- Volunteers
- 156 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Depressive Symptoms
Morning Activation to Improve Mood After Stroke
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a six-week behavioral intervention designed to improve mood and daily functioning in adults who have experienced a stroke and report…
- Trial name
- NCT07719517
- Testing
- Morning Activation Program, Health Education Program
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Psychological Distress, Depressed Mood
Ecological Momentary Intervention (E-Breathing) to Reduce Psychological Distress in Adolescents
A two-arm randomized controlled trial (RCT) will be conducted to test a mobile-based intervention, E-breathing, for early detection and intervention to address psychological distress in at-risk adolescents in Hong Kong.
- Conditions
- Psychological Distress, Depressed Mood, Anxiety, Stress
- Trial name
- NCT07717112
- Testing
- Slow-paced breathing via ecological momentary intervention, Ecological momentary assessments
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The Hong Kong Polytechnic University
Dyslexia
Validating a Neurocognitive Remediation Model for Visual-Attentional Pathway in Chinese Developmental Dyslexia
Developmental dyslexia is a common and serious specific learning disability affecting up to one in eight children in Hong Kong, with profound consequences for academic success and personal well-being.
- Trial name
- NCT07707700
- Testing
- Action video game intervention group, Active Control (Non-Action Video Game) Group
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The Hong Kong Polytechnic University
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Effect of Inspiratory Muscle Training on Knee Osteoarthritis Pain
Knee osteoarthritis (KOA) is a common joint disease that causes chronic pain and limits daily activities. Current treatments, such as painkillers or surgery, have limitations like side effects or high costs.
- Trial name
- NCT07698418
- Testing
- Inspiratory muscle training
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Sarcopenic Obesity
Effects of the EatWelLog App on Diet Management for Older Adults With Sarcopenic Obesity
Sarcopenic obesity, characterised by concurrent reduced muscle mass and excess body fat, affects 11% of older adults worldwide, rising to 23% in those over 75.
- Trial name
- NCT06360432
- Testing
- Dietary modification program, Exercise training, The EatWellLog App
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Diabetes
Mindful Eating Study for Adults With Diabetes and Weight Concerns in Hong Kong
Objectives: To assess the effect of a digital Mindfulness-Based Eating Awareness Training (MB-EAT) intervention on anthropometric measures, glycaemic control, eating behaviours, psychological health and hormones regulating stress…
- Trial name
- NCT07692386
- Testing
- MB-EAT, control group
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Effects of rTMS Combined With Dual-Task Gait Training on Walking and Cognition After Stroke
This randomized, double-blind, placebo-controlled trial will investigate whether repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) can enhance the effects of dual-task gait…
- Trial name
- NCT07356687
- Testing
- active rTMS with dual-task training
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The Hong Kong Polytechnic University
Undergraduate Nursing Students, Nursing Students
A Community Practice Program to Enhance Nursing Students' Career Motivation in Geriatric Nursing
The nursing students' community practice program is nested within the mHealth-based healthcare professional-lay health worker partnership program (mHLPP).
- Trial name
- NCT07689734
- Testing
- A PERMA Model-Based Community Practice Program, Wait-list Comparator, A COM-B Model Based Community Practicum Program
- Where
- Hong Kong
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Post Stroke
An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients
The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage…
- Trial name
- NCT07691411
- Testing
- Ecological Momentary Assessment based Self-management Program
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Impoverished Population, Older Adults (60 - 85 Years Old)
An mHealth-based Healthcare Professional-Lay Health Worker Partnership Program (mHLPP)
The project aimed at training female food delivery workers from Food Angel to perform basic health checks for older adults living alone in the community.
- Trial name
- NCT07691398
- Testing
- mHealth-Based Healthcare Professional-Lay Health Worker Partnership Program (mHLPP)
- Where
- Hong Kong
- Volunteers
- 230 people
- Sponsor
- The Hong Kong Polytechnic University
Sleep, Circadian Rhythm
Morning Bright Light Therapy and Daytime Functioning in University Students
This study tests whether a week of morning bright light therapy changes how well healthy young adults sleep and how alert, positive, and mentally sharp they feel during the day.
- Conditions
- Sleep, Circadian Rhythm, Daytime Sleepiness, Mood
- Trial name
- BLIGHT (NCT07685262)
- Testing
- Bright light therapy (10,000 lux light box)
- Where
- Hong Kong
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronotype, Circadian Rhythm
Chronotype Alignment and Time Perception
People differ in chronotype - whether they function best in the morning ("larks") or the evening ("owls"). This study asks whether the match or mismatch between a person's chronotype and the time of day at which they are tested…
- Conditions
- Chronotype, Circadian Rhythm, Sleep, Time Perception
- Trial name
- NCT07677111
- Testing
- Morning test session (about 08:00), Evening test session (about 22:00)
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Health Adult Subjects
Prefrontal Neuroplasticity and Coping Strategies in Healthy Population
The current study serves as a pilot for the GRF project "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS." The project examines whether intermittent theta-burst stimulation (iTBS)…
- Trial name
- NCT07433829
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Ankylosing Spondylitis (AS), Mental Health
An Ecological Momentary Intervention for Mental Health in Individuals With Ankylosing Spondylitis
Ankylosing spondylitis is a chronic inflammatory rheumatic disease associated with pain, stiffness, reduced mobility, and impaired quality of life.
- Trial name
- NCT07647965
- Testing
- Ecological Momentary Intervention, Attention Control Group
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Upper Limb Rehabilitation
Exoneuromusculoskeleton for Upper Limb Rehabilitation After Stroke
A new clothing robotic arm was developed for multi-joint coordinated upper limb rehabilitation after stroke. Patients after stroke will be recruited to evaluate the rehabilitation effectiveness of the device assisted upper limb…
- Trial name
- NCT03752775
- Testing
- Robot assisted upper limb rehabilitation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- The Hong Kong Polytechnic University