Clinical trials: sponsored by Tongji Hospital
Hepatocellular Carcinoma
A Study to Evaluate Sintilimab Plus Lenvatinib as Adjuvant Therapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis (PVTT) After Surgical Resection
To compare the impact on recurrence risk of adjuvant Sintilimab (a recombinant fully human anti-PD-1 monoclonal antibody) plus Lenvatinib for patients with hepatocellular carcinoma and portal vein tumor thrombus (PVTT ) after…
- Trial name
- NCT06089382
- Testing
- Sintilimab, Lenvatinib, Transarterial Chemoembolization (TACE)
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Tongji Hospital
Remimazolam, Awake Endotracheal Intubation
Compatible Effect of Remimazolam Besylate Combined With Afentanil for ATI
1. To study the pharmacokinetics between remimazolam besylate and alfentanil; 2. To determine the optimal dosage of the two drugs in awake endotracheal intubation; 3. To provide clinical guidance for awake endotracheal intubation.
- Trial name
- NCT06026566
- Testing
- Dos of Afentanil 20, Dos of Afentanil 30, Dos of Afentanil 40
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Tongji Hospital
Remimazolam, Anesthesia
The Dose Range of Remimazolam Besylate in Different Age Groups
This is a multicenter, randomized, parallel, controlled clinical study of patients at different ages underwent elective non-cardiac surgery under general anesthesia.
- Trial name
- NCT06009991
- Testing
- Remimazolam besylate, Propofol
- Where
- China
- Volunteers
- 1,876 people
- Sponsor
- Tongji Hospital
Develop a Nomogram
Development and Validation of a Nomogram Predicting the Probability of in Hirschsprung Children Following Surgery
Postoperative soiling is a common complication following Hirschsprung disease [HSCR] surgery. The aim of this study was to develop a nomogram for predicting the probability of postoperative soiling in patients aged >1 year…
- Trial name
- NCT06025188
- Testing
- training set
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital
Supraclavicular Brachial Plexus Block
Perfusion Index as an Objective Measure for Supraclavicular Brachial Plexus Block in Pediatric Patients
The aim of the present study is to evaluate the effects of supraclavicular brachial plexus block using perfusion index in pediatric patients undergoing Upper limb surgery.
- Trial name
- NCT04216823
- Testing
- perfusion index
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Tongji Hospital
Tuberculosis
A Retrospective Study on the Treatment Pattern and Clinical Prognosis of Severe Tuberculosis Patients
This is a retrospective clinical study to analyze the clinical characteristics, complications, and effects of different treatment options on long-term prognosis of severe tuberculosis patients.
- Trial name
- NCT06021041
- Where
- 2 sites in China
- Volunteers
- 900 people
- Sponsor
- Tongji Hospital
HFRS
A Retrospective Cohort Study of HFRS
The goal of this retrospective cohort study is to learn about the clinial characteristics of HFRS patients, explore the risk factors of the occurrence and death of HFRS, and build a risk prediction model for HFRS.
- Trial name
- NCT06020326
- Where
- 8 sites in China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Central Nervous System Tuberculosis
A Retrospective Study of Treatment Patterns and Clinical Outcomes in Patients With Central Nervous System Tuberculosis
This is a retrospective clinical study to analyze the clinical characteristics, complications, and effects of different treatment options on long-term prognosis in patients with central nervous system tuberculosis.
- Trial name
- NCT06011915
- Where
- 2 sites in China
- Volunteers
- 638 people
- Sponsor
- Tongji Hospital
Severe Fever With Thrombocytopenia Syndrome
A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome
This is a multi-center, retrospective clinical study to analyze the clinical features, laboratory indicators, imaging changes, treatment options and long-term prognosis in patients with sever fever with thrombocytopenia syndrome.
- Trial name
- NCT06011902
- Where
- 8 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Tongji Hospital
Pain, Chronic
Safety and Efficacy of Low-intensity Laser Therapy in the Treatment of Chronic Musculoskeletal Pain
This study is a multicenter, prospective, randomized, controlled research design. This study takes classic NSAIDs treatment as a control, and it will take patients' pain relief, functional improvement, sleep quality improvement…
- Trial name
- NCT06009900
- Testing
- Low intensity laser treatment, Non-steroidal drug (Celecoxib) group
- Where
- 5 sites in China
- Volunteers
- 860 people
- Sponsor
- Tongji Hospital
HFRS (Hemorrhagic Fever With Renal Syndrome)
Efficacy of Intravenous Immunoglobulin in Patients With Hemorrhagic Fever With Renal Syndrome: a Prospective Study
The goal of this randomized study to test the efficacy of different doses of IVIG (intravenous immunoglobulin) in the treatment of severe HFRS（hemorrhagic fever with renal syndrome）, and provide new clinical ideas for the…
- Trial name
- NCT06009042
- Testing
- IVIG 20g/d, IVIG 10g/d
- Where
- 9 sites in China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Kidney Transplant Rejection, Kidney Transplant Infection
Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients
The goal of this observational study is to learn about dynamic changes of Torquetenovirus (TTV) load in Chinese renal transplant recipients.
- Conditions
- Kidney Transplant Rejection, Kidney Transplant Infection, Virus, Immunosuppression
- Trial name
- TTV (NCT05727709)
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- Tongji Hospital
Drug Effect
Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children
To observe the sedative effect and safety of remiazolam combined with small dose of esketamine in painless bidirectional endoscopy in children, and to provide a more reasonable and safe sedative and analgesic regimen for…
- Trial name
- NCT05686863
- Testing
- Remimazolam, Esketamine, Propofol
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Tongji Hospital
COVID-19
Long-term Follow-up Study of COVID-19
The goal of this observational study is to learn the long-term prognosis of patients and the clinical characteristics of complications, which is of great significance for treatment of novel coronavirus infection pneumonia.
- Trial name
- NCT05986435
- Where
- 2 sites in China
- Volunteers
- 5,700 people
- Sponsor
- Tongji Hospital
Endocrine Diseases
Performance of the Diagnostic Value of Bone Age Assessment Software Based on Deep Learning in Chinese Children
High accuracy and precision bone age assessment is very important for the diagnosis and treatment monitoring of various pediatric diseases.
- Trial name
- NCT05137301
- Testing
- X-ray bone age instrument
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Small for Gestational Age Infant, Growth Hormone Treatment
A Real World Study of the Effect of Early PEG-rhGH Therapy on Cognitive Development of SGA Infants
Cognitive impairment is independently related to low birth weight, low birth length and small head circumference. SGA children who have not experienced height and / or head circumference catch-up have the worst cognitive…
- Conditions
- Small for Gestational Age Infant, Growth Hormone Treatment, Cognitive Developmental Disorder
- Trial name
- NCT05144035
- Testing
- PEG-rhGH
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Tongji Hospital
Acute Kidney Injury
Effects of BRS and LRS on Postoperative Acute Kidney Injury
1. Title: Effects of Sodium Bicarbonate Ringer's Injection and Sodium Lactated Ringer's Injection on postoperative acute kidney injury in patients undergoing major abdominal surgery: a randomized, controlled, open-label clinical…
- Trial name
- BRS/LRS (NCT04835038)
- Testing
- Sodium Bicarbonate Ringer's Injection, Sodium Lactated Ringer's Injection
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Tongji Hospital
Nutrition Supporting, Hirschsprung Disease
Nutrition Support for Hirschsprung Disease
A multi-center, prospective,randomized, non-blind, controlled study was conducted to investigate the effects of different pre-operative nutritional support modes on perioperative nutritional status, surgical treatment success…
- Conditions
- Nutrition Supporting, Hirschsprung Disease, Infants, Prospective Study
- Trial name
- NCT04598841
- Testing
- supplement nutritional supporting
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Tongji Hospital
Cardiomyopathy
Exome Sequencing Study in Cardiomyopathy to Identify New Risk Variants
Genetic mutations has been proved to be associated wth the onset of cardiomyopathy. In the present study, we intend to identify new related variants or genes.
- Trial name
- NCT03754101
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
HER2-Positive Cancer
68Ga-HER2 Affibody PET/CT Imaging for HER2-Positive Cancer Patients
The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies. immunohistochemistry (IHC) or amplification by fluorescence in situ hybridization (FISH) is currently the most…
- Trial name
- NCT05535621
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital