Clinical trials: sponsored by Tongji Hospital
Pancreatic Carcinoma, Laparoscopic
Comparing Laparoscopic and Open Surgery for Pancreatic Carcinoma
Background: Pancreatic cancer (PC) is one of the most aggressive malignant neoplasms with poor outcomes. Pancreatoduodenectomy (PD) is the only curative treatment for PC.
- Conditions
- Pancreatic Carcinoma, Laparoscopic, Pancreaticoduodenectomy
- Trial name
- NCT03785743
- Testing
- TLPD Surgery, OPD Surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Ovarian Cancer
A Non-interventional Registry Study of Fluzoparib in the Treatment of Ovarian Cancer
Ovarian cancer is one of the most fatal malignant tumors that threaten women's health. The incidence rate is the third place among the female reproductive system malignant tumors, and the mortality rate ranks the first in…
- Trial name
- NCT05206890
- Testing
- fluzoparib monotherapy or combination therapy
- Where
- China
- Volunteers
- 490 people
- Sponsor
- Tongji Hospital
Squamous Intraepithelial Lesions, Laser Burn
Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions
Using multiple targeting CO2 laser ablation to treat the precancerous lesion of the female lower anogenital tracts and analyzing the data collected in the study, we aim to form the standard strategy of laser ablation method to…
- Trial name
- NCT05170620
- Testing
- laser ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Diabetic Nephropathies
The Effects of TMZ on Diabetic Nephropathy
With the improvement of people's living standard, the prevalence of Diabetes is increasing year by year. In present, 350 million people worldwide are suffering from diabetes, and by 2035, there will be as high as 600 million.
- Trial name
- NCT05147194
- Testing
- Trimetazidine
- Volunteers
- 150 people
- Sponsor
- Tongji Hospital
Acute Coronary Syndrome
Comparison Of Efficacy and Safety Between Ticagrelor and Clopidogrel In Chinese
This is a prospective, single-center study to assess the long- and short-term outcomes of ticagrelor vs clopidogrel in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention.
- Trial name
- COSTIC (NCT03239067)
- Where
- China
- Volunteers
- 9,040 people
- Sponsor
- Tongji Hospital
Ovarian Cancer
Detection of Ovarian Cancer Using an Artificial Intelligence Enabled Transvaginal Ultrasound Imaging Algorithm
Ovarian cancer is relatively rare but fatal with an annual incidence rate of 11.8 per 100 000 and a high mortality-to-incidence ratio of >0.6.
- Trial name
- NCT04214782
- Testing
- Artificial Intelligence Enabled Transvaginal Ultrasound Imaging algorithm
- Volunteers
- 10,000 people
- Sponsor
- Tongji Hospital
Gynecologic Cancer, Ovarian Cancer
Clinical Characters of the Diagnosis and Treatment of Gynecological Malignant Tumors in China : A Real World Study
Gynecological tumors are serious threats to women's health. Ovarian Cancer (OC), uterine and cervical malignancies (c-uc) are common gynecological malignancies, which are featured by high morbidity and mortality, limited…
- Conditions
- Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT04214964
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Tongji Hospital
Gynecological Cancer
The Safety of Chemotherapy for Patients With Gynecological Malignancy in High-risk Region of COVID-19
A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) emerged at December 2019 in Wuhan, China, and soon caused a large global outbreak.
- Trial name
- NCT04341480
- Testing
- Chemotherapy
- Where
- China
- Volunteers
- 305 people
- Sponsor
- Tongji Hospital
Breast Cancer
SEMA4C as a Relapse Biomarker in Breast Cancer
Breast cancer remains the most common cancer in women worldwide. Semaphorin4C (SEMA4C) has previously been identified as a highly expressed protein by breast cancer-associated lymphatic endothelial cells (LECs).
- Trial name
- NCT03663153
- Testing
- SEMA4C high value follow-up group, SEMA4C low value follow-up group
- Volunteers
- 4,200 people
- Sponsor
- Tongji Hospital
Hirschsprung Disease, Bowel; Perforation, Fetus or Newborn
Risk Factors of Perforated HSCR in Neonates
Hirschsprung's disease (HSCR) is a common digestive malformation with radiographic evidence of distal bowel obstruction and clinical signs of abdominal distension, vomiting, constipation, and failure to pass meconium.
- Trial name
- NCT05044741
- Testing
- Emergency surgical enterostomy
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital
Esophageal Squamous Cell Carcinoma, Neoadjuvant Therapies
Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study
To purpose of this study is to access the safety and efficacy of neoadjuvant Immunotherapy (PD-1 / PD-L1) combined with chemotherapy for locally advanced thoracic esophageal squamous cellcarcinoma.
- Trial name
- NICCE (NCT05028231)
- Testing
- Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Heart Failure
The Effects of Neuraminidase Inhibitor Oseltamivir in Patients With Chronic Heart Failure
Heart failure (HF) is a complex syndrome with increasing incidence and high rates of mortality and hospitalization. Although inhibitors of angiotensin converting enzyme (ACE), β-blockers and aldosterone-receptor blockers have…
- Trial name
- NCT05008679
- Testing
- Oseltamivir
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Tongji Hospital
Calcitonin Secretion Disorder, Post-operative Atrial Fibrillation
Calcitonin Level and New-onset of Post-Operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is one of the common complicaiton following cardiac surgery, occurring in approximately 20%-40% patients.
- Trial name
- NCT04993456
- Testing
- Caridac surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Heart Failure
Effect of Levosimendan on miRNAs Regulation in the Failing Hearts
Chronic heart failure is the terminal stage of various cardiovascular diseases. It is characterized with high fatality rate and high recurrence rate, which brings a heavy economic burden to patients and society.
- Trial name
- NCT04950569
- Testing
- levosimendan
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Tongji Hospital
Craniopharyngioma, Apoplexy
Craniopharyngioma With Tumoral Hemorrhage
Clinical data of 185 consecutive patients receiving resective operation with a pathological diagnosis of craniopharyngioma in our hospital between January 2013 and February 2021 were collected.
- Trial name
- NCT04937335
- Testing
- intratumoral hemorrhage
- Volunteers
- 185 people
- Sponsor
- Tongji Hospital
Liver Failure, Thrombocytopenia
Avatrombopag in Patients With End-stage Liver Disease and Thrombocytopenia
End stage liver disease is prone to thrombocytopenia. This study is a multi-center, randomized, prospective, randomized controlled Phase IV Clinical trial to discuss the Efficacy and Safety of Avatrombopag in Patients with…
- Conditions
- Liver Failure, Thrombocytopenia, Decompensated Cirrhosis
- Trial name
- NCT04906083
- Testing
- Avatrombopag, Standard medical treatment
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tongji Hospital
Nerve Block, Surgical Conditions
Effect of the Sheath of Rectus Abdominis Block Combined With the Transverse Plane
The situation of demand for surgical conditions is quite high when lymph node resection involved in the surgery type, especially abdominal aortic lymph node dissection, and commonly, the surgeons complained about the interference…
- Trial name
- NCT04850404
- Testing
- abdominal nerve block
- Volunteers
- 42 people
- Sponsor
- Tongji Hospital
Non Small Cell Lung Cancer
Radiotherapy Combined With Immunotherapy for Brain Metastases of Non-small Cell Lung Cancer
This is a Retrospective, Multicenter, Controlled Study to Evaluate Immunotherapy and Radiotherpay for Brain Lesions as a Potential Treatment for Patients with Brain Metastasis in non-small cell lung cancer
- Trial name
- NCT04835025
- Testing
- PD-1/PD-L1 inhibitor
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Stage IV Non-small Cell Lung Cancer
Maintenance Targeted Therapy With or Without Stereotactic Body Radiation Therapy for Stage IV Non-small Cell Lung Cancer
This is a Prospective, Multicenter, Randomized Controlled study to evaluate Stereotactic Body Radiation Therapy (SBRT) as a potential treatment for stage IV non-small cell lung cancer (NSCLC) that has a mutated epidermal growth…
- Trial name
- NCT03595644
- Testing
- SBRT+TKI, TKI
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Tongji Hospital
Gastroesophageal Varices, Hypersplenism
EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal Hypertension
This study aims to evaluate the efficiency of EUS-guided combination therapy (EUS-guided PSE + EUS-guided treatment of varices) to EUS-guided treatment of varices alone in cirrhotic patients with portal hypertension who have…
- Conditions
- Gastroesophageal Varices, Hypersplenism, Portal Hypertension
- Trial name
- NCT04692805
- Testing
- coils, cyanoacrylate glue
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Tongji Hospital