Clinical trials: sponsored by Tongji Hospital
COVID-19
A Pilot Study of Sildenafil in COVID-19
Observe the efficacy and safety of G1(Sildenafil citrate tablets) in patients with COVID-19 under clinical actual diagnosis and treatment conditions
- Trial name
- NCT04304313
- Testing
- Sildenafil citrate tablets
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Tongji Hospital
2019-nCoV
A Prospective/Retrospective,Randomized Controlled Clinical Study of Antiviral Therapy in the 2019-nCoV Pneumonia
At present, there is no specific and effective antiviral therapy.In this study, an open, prospective/retrospective, randomized controlled cohort study was designed to compare the efficacy of three antiviral drugs in the treatment…
- Trial name
- NCT04255017
- Testing
- Abidol hydrochloride, Oseltamivir, Lopinavir/ritonavir
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tongji Hospital
Covid-19, SARS
Tocilizumab vs CRRT in Management of Cytokine Release Syndrome (CRS) in COVID-19
Some patients infected with the COVID-19 can develop uncontrolled immune response, leading to potentially life-threatening damage to lung tissue. Tocilizumab was first approved by the U.S.
- Conditions
- Covid-19, SARS, Cytokine Storm, Cytokine Release Syndrome
- Trial name
- TACOS (NCT04306705)
- Testing
- Tocilizumab, Standard of care, Continuous renal replacement therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
2019-nCoV Severe Pneumonia
The Efficacy of Different Hormone Doses in 2019-nCoV Severe Pneumonia
At present, there is no specific and effective antiviral therapy.In this study, an open, prospective/retrospective, randomized controlled cohort study was designed to compare the efficacy of different hormone doses in the…
- Trial name
- NCT04263402
- Testing
- Methylprednisolone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
2019-nCoV Pneumonia
A Randomized,Open,Controlled Clinical Study to Evaluate the Efficacy of ASC09F and Ritonavir for 2019-nCoV Pneumonia
Based on oseltamivir treatment, evaluate the efficacy and safety of ASC09/ritonavir compound tablets(ASC09F) or ritonavir tablets for 2019-nCoV infection patients.
- Trial name
- NCT04261270
- Testing
- ASC09F+Oseltamivir, Ritonavir+Oseltamivir, Oseltamivir
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tongji Hospital
Fulminant Myocarditis
Clinical Assessment of New Treatment Regimen for Adult Fulminant Myocarditis
This is a retrospective cohort study to assess the clinical outcome of patients with fulminant myocarditis using "Life-support Based Comprehensive Treatment Regimen" and conventional therapy.
- Trial name
- NCT03268642
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tongji Hospital
Complications of Treatment, Complication of Surgical Procedure
A Trial on Treatments of Hirschsprung Allied Disease
The present study was designed to compare the efficacy of conservative treatment to operative treatment for improvement of constipation symptoms in children with Hirschsprung allied disease
- Conditions
- Complications of Treatment, Complication of Surgical Procedure, Megacolon, Not Hirschsprung
- Trial name
- NCT02212054
- Testing
- conservative, operative
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Pancreaticoduodenectomy
Investigation of Pancreaticoduodenectomy
The investigators intend to conduct a multicentre, big-sample, retrospective study to analysis the surgery results of pancreaticoduodenectomy and compare the different suture technique.
- Trial name
- NCT03791450
- Where
- China
- Volunteers
- 10,085 people
- Sponsor
- Tongji Hospital
COVID-19, Recombinant Human Interferon α1β
Efficacy and Safety of IFN-α2β in the Treatment of Novel Coronavirus Patients
New coronavirus infection is an important cause of public health emergencies at home and abroad, which seriously affects people's health and social stability.
- Trial name
- NCT04293887
- Testing
- Recombinant human interferon α1β
- Volunteers
- 328 people
- Sponsor
- Tongji Hospital
Neck Pain
Addition of 3D Posture Corrective Orthosis to A Multimodal Program of Treatment Of NSNP.
Nonspecific neck pain (NSNP) is one of the most common musculoskeletal problems treated by orthopaedic physicians and physiotherapists .
- Trial name
- NCT03331120
- Testing
- ambulatory mirror image functional re-training through wearing 3D adjustable cervicothoracic Posture Corrective Orthotic(CTPCO)
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tongji Hospital
Multiple Pulmonary Nodules
A Real-world Study for Patients With Multiple Pulmonary Ground-glass Nodules
The purpose of this study is to actively monitor patients with multiple pulmonary Ground-glass Nodules (GGNs), in order to provide evidence for multiple GGNs treatment.
- Trial name
- NCT04192201
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Chronic Hepatitis b
TAF Real World Study for Universal Effectiveness
This study is a multi-center, prospective, real-world study, males and non-pregnant, non-lactating female HBeAg positive or negative patients (above 18 years of age) who were mono-infected with HBV, either NA treatment-naïve or…
- Trial name
- TRUE (NCT03752658)
- Testing
- Tenofovir Alafenamide
- Where
- 7 sites in China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Esophagus Cancer
Neoadjuvant Chemoradiotherapy Combined With PD-1 Antibody in Locally Advanced Esophageal Cancer
This study will evaluate the safety and feasibility of preoperative immune checkpoint therapy with concurrent Chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma.
- Trial name
- T+TP (NCT04177875)
- Testing
- Teripalimab
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Urolithiasis, Sepsis
Prediction of Sepsis After Flexible Ureteroscopy
Sepsis is a lethal complication of flexible ureteroscopy. The aim of this study is to identify predictors of sepsis after flexible ureteroscopy in patients with solitary proximal ureteral stones.
- Conditions
- Urolithiasis, Sepsis, Surgery--Complications
- Trial name
- NCT04157452
- Testing
- flexible ureteroscopy
- Where
- China
- Volunteers
- 759 people
- Sponsor
- Tongji Hospital
Prostatic Neoplasms
Radical Prostatectomy Versus Radical Radiotherapy for Locally Advanced Prostate Cancer
This prospective, open randomized clinical trial seeks to investigate whether radical prostatectomy with androgen deprivation therapy improves prostate-cancer specific survival and quality of life in comparison with radical…
- Trial name
- NCT04093375
- Testing
- Radical Prostatectomy, Radical Radiotherapy
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital
Intestinal Neoplasms
Study of Small Bowel Tumor With Dual-phase Enhanced Computed Tomography (CTE) and Magnetic Resonance Enterography (MRE)
Purpose: To compare the accuracies of computed tomographic (CT) enterography and magnetic resonance (MR) enterography for the detection and radiomics characterization of small-bowel tumors (including gastrointestinal stromal…
- Trial name
- NCT03659357
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Tongji Hospital
Lung Cancer Stage I
Clinical Evaluation of Vagal Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer
Through prospective, randomized and controlled clinical study, patients with early lung cancer who do not need lymph node dissection according to routine diagnosis and treatment were selected.
- Trial name
- CEVNPIMISELC (NCT04125979)
- Testing
- In minimally invasive surgery，Vagus nerve preservation, In minimally invasive surgery，Vagus nerve is not preserved
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Ulcerative Colitis
Safety and Efficacy of Heterologous FMT by SQIMC-md Capsule in Mild-moderate Ulcerative Colitis Patients
This study aims to assess the safety and efficacy of heterologous fecal microbiota transplantation (FMT) by Standardized Quantitative multi-donor Intestinal Microbiota Capsule (SQIMC-md) in mild-moderate ulcerative colitis…
- Trial name
- SQIMC-md (NCT04034758)
- Testing
- Standardized Quantitative multi-donor Intestinal Microbiota Capsule (SQIMC-md)
- Volunteers
- 99 people
- Sponsor
- Tongji Hospital
Urolithiasis
Treatment of Calculous Pyonephrosis With 0.5% Iodophors for I-stage PCNL
Calculous Pyonephrosis is a special type of urinary tract calculi, which is also common in clinical practice. If pyonephrosis is not treated in time, it will have a serious impact on the kidney function.
- Trial name
- NCT03805542
- Testing
- 0.5% Iodophors
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Tongji Hospital
Nutrition
A Study on Nutrition Support Therapy of Patients With Liver Failure
This study is a Clinical trial to assess the efficacy of nutrition support therapy of patients with liver failure. Patients were randomized to one of 2 groups to receive different nutrition and energy support treatment.
- Trial name
- NCT03944330
- Testing
- standard hospital diet
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital