Clinical trials: sponsored by Tongji Hospital
Chronic Hepatitis c
Glecaprevir/Pibrentasvir Real-world Study in China
To evaluate the efficacy, adverse effect, short - and long-term outcomes of Glecaprevir/Pibrentasvir for the treatment of chronic hepatitis C (non-cirrhotic or compensatory cirrhosis)in China through a real-world study
- Trial name
- NCT03941821
- Testing
- Glecaprevir/Pibrentasvir
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Environmental Exposure, Infertility
The Effect of Periconceptional Phthalates Exposure on Couples' Reproductive Health
The study is a prospective cohort study, which is aiming to explore periconceptional phthalates exposure and its potential epigenetic effect on fertility, embryo development, and neonatal outcomes.
- Trial name
- NCT03679000
- Where
- China
- Volunteers
- 2,122 people
- Sponsor
- Tongji Hospital
Heart Failure
Evaluation of Clinical and Genetic Modifiers of Long-term Survival in Heart Failure
The purpose of this study is to evaluate the beta-adrenergic receptor gene polymorphisms in the long-term effects of beta-blockade in patients with chronic heart failure.
- Trial name
- NCT03461107
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Tongji Hospital
Glioma of Brain
Visual Study of Molecular Genotype in Glioma Evolution
The key molecular changes in the progression of glioma are closely related to tumor heterogeneity, pathological grade, precision treatment and prognosis of glioma.
- Trial name
- NCT03750890
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Diabetic Cardiovascular Autonomic Neuropathy
Risk Analysis for Diabetic Cardiovascular Autonomic Neuropathy
A large-scale, community-based, cross-sectional study was conducted to explore the extent to which risk factors associated with diabetic cardiovascular autonomic neuropathy (DCAN) in general Chinese population.
- Trial name
- NCT02461472
- Testing
- not intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Gallbladder Diseases, Healthy
Multicenter Prospective Cohort Study of Risk Factors for Gallbladder Cancer
This trial is a prospective study, the main purpose of the study is to investigate the association between benign gallbladder disease and gallbladder carcinoma; to explain the timing of intervention, intervention and early…
- Trial name
- NCT03762837
- Testing
- Benigh gallbladder diseases
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Meniscus Injury
Safety Observation on hESC Derived MSC Like Cell for the Meniscus Injury
human embryonic stem cell derived mesenchymal stem cells like cell for the meniscus injury, and observe the safety of the cells for meniscus injury
- Trial name
- NCT03839238
- Testing
- hESC derived MSC like cell
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Tongji Hospital
NSCLC
Docetaxel Combined With Carboplatin Plus Anlotinib as First Line Treatment in NSCLC
Anlotinib which has shown an affirmatory efficacy in ALTER0303 controlled trial as a 3rd-line treatment on advanced NSCLC is a tyrosine kinase inhibitor with a favorable safety profile in phase I trial which mainly targets…
- Trial name
- ALTER-L013 (NCT03799601)
- Testing
- Anlotinib, Docetaxel, Carboplatin
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Tongji Hospital
Leukemia, Lymphoma
CD19-directed CAR T Cells Therapy in Relapsed/Refractory B Cell Malignancy
Relapsed/refractory leukemia and lymphoma lack effective treatment. The cancer immunotherapy with chimeric antigen receptor (CAR) T cells provides a potent new approach for them.
- Trial name
- NCT02537977
- Testing
- CD19-directed CAR-T cells
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Pancreatic Fistula, Pancreatic Neoplasms
Greater Omentum Binding to the Pancreatic Stump to Prevent Pancreatic Fistula Following Distal Pancreatectomy
Background and aim: Distal pancreatectomy (DP) is often performed for primary benign or malignant lesions occurred in the body or tail of the pancreas.
- Trial name
- NCT03752086
- Testing
- greater omentum binding, Pancreatic stump exposed without omentum binding
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Mediastinal Nodes
Application Study of 12G Pigtail Catheter Used for Post-operative Drainage After Thoracoscopic Surgery for Mediastinal Nodes
Pigtail catheter(PC) has been used for thoracic drainage in the patients with pneumothorax or traumatic hemothorax/hemopneumothorax, and some study indicated that PC could obtain similar outcomes when comparing with chest…
- Trial name
- NCT03743389
- Testing
- 12G pigtail catheter, 16F chest tube
- Volunteers
- 80 people
- Sponsor
- Tongji Hospital
Hypertrophic Cardiomyopathy
Outcome of Different Pathogenic Mutations in Hypertrophic Cardiomyopathy
This is a prospective, single-center study to assess clinical phenotype and prognosis of different pathogenic mutations in Chinese patients with hypertrophic cardiomyopathy.
- Trial name
- NCT03726424
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
CT Images of Internal Hernia, Clinical Outcomes
CT and Clinical Features of Internal Hernia
Researchers retrospectively reviewed patients with internal hernia that confirmed by surgical exploration between Feb. 2012 and Feb. 2018.
- Trial name
- NCT03703752
- Testing
- Multi-detector CT scan
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Tongji Hospital
End Stage Liver Disease, Infection
A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIR Study)
The term of End Stage of Liver Disease (ESLD) was raised in 80's of 20 Century, but without a restrict definition. Infections are the cause and effect in occurrence and development of ESLD, which not only induce or exacerbate…
- Trial name
- NCT03363451
- Testing
- Antibiotics
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Vascular Diseases
Superior Mesenteric Artery Dissection
This study investigate CT images of patients with spontaneous isolated superior mesenteric artery dissection (SISMAD). The investigators also further analyze the CT morphological differences between different options, aiming to…
- Trial name
- NCT03669380
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tongji Hospital
End Stage Liver Disease, Infection
A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIP Study)
Spontaneous bacterial peritonitis (SBP) is a common complication of end-stage liver disease due to various causes. The initial anti-infective medication is appropriate and the patient's survival rate is closely related.
- Conditions
- End Stage Liver Disease, Infection, Spontaneous Bacterial Peritonitis
- Trial name
- NCT03362632
- Testing
- Antibiotics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tongji Hospital
Urological Disease, Anesthesia
To Map Human Lower Thoracic Dermatomes by Epidural Block
Significant differences exist among various dermatome maps. In addition, there were no anatomical landmarks to evaluate the dermatome at the back.
- Trial name
- LTDEP (NCT03022136)
- Testing
- cold sensation method
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Non-small Cell Lung Cancer
A Study to Evaluate Effectiveness of Sublobar Dissection in Patients With Non-small Cell Lung Cancer
A study to evaluate effectiveness of sublobar dissection in patients with non-small cell lung cancer
- Trial name
- NCT03427567
- Testing
- Sublobar dissection
- Where
- 10 sites in China
- Volunteers
- 3,902 people
- Sponsor
- Tongji Hospital
Hepatitis B, Chronic
Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patients
This study is a multi-center, randomized, prospective, open-label Phase IV Clinical trial to evaluate efficacy and safety of interferon alfa-2b therapy combinated with interleukin 2 and hepatitis B therapeutic vaccine versus…
- Trial name
- NCT02360592
- Testing
- Entecavir, Interferon alfa-2b, Interleukin 2
- Where
- 12 sites in China
- Volunteers
- 94 people
- Sponsor
- Tongji Hospital
Fever of Unknown Origin
A Two-step Method Apparently Improved the Physicians' Level of Diagnosis Decision-making for Adult Patients With FUO
The purpose of this study is to determine whether two-step method of diagnostic strategy is effective in the diagnosis and treatment of fever of unknown origin (FUO).
- Trial name
- NCT02035670
- Testing
- Two-step diagnostic strategy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital