Clinical trials: sponsored by Tongji Hospital
Chronic Hepatitis B
A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B
The aim of the prospective real-world study is to evaluate whether sequential combination therapy with pegylated interferon plus entecavir/tenofovir could induce higher rates of HBsAg loss in nucleoside-treated patients with…
- Trial name
- COST (NCT03357822)
- Testing
- Pegylated interferon, Entecavir, Tenofovir disoproxil fumarate
- Where
- 12 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Tongji Hospital
Gallbladder Cancer, Surgery
Three Dimension Laparoscopic Versus Open Surgery for Gallbladder Carcinoma
Introduction: Surgery is the only potential curative approach for the highly lethal gallbladder carcinoma. The laparoscopic surgery has developed rapidly since invented.
- Trial name
- NCT03491878
- Testing
- Three dimensional laparoscopic, Open
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Nasogastric Tube Decompression, Pancreatic Surgery
Nasogastric Tube in Pancreatic Surgery
Introduction: The value of routine nasogastric tube (NGT) decompression after pancreatic surgeries is not yet established. Previous studies in the setting of abdominal surgery suggested that the use of NGT does not accomplish any…
- Trial name
- NCT03462602
- Testing
- NGT group, non-NGT group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Common Bile Duct Stone
Treatment of Common Bile Duct Stones
ABSTRACT Introduction: Common bile duct (CBD) stone is a common clinical situation, especially in Asia area. Laparotomy and laparoscopic surgical procedure are often used for treatment.
- Trial name
- NCT03442205
- Testing
- LC + LCBDE + ENBD + primary closure of CBD, ERCP technique + LC, LC + LCBDE + primary closure of CBD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Pelvic Diseases, Abdominal Diseases
The Study of Functional Magnetic Resonance Imaging in Abdominal and Pelvic Diseases
The purpose of this study is to study the diagnostic efficiency of functional magnetic resonance imaging in Abdominal and Pelvic Diseases.
- Trial name
- NCT02337777
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Vitamin D Deficiency, Infertility
Vitamin D Deficiency of Couples and Infertility
Between March 2016 and March 2017, we performed a large retrospective, non-interventional, single-center cohort study and measured 25(OH)D3 plasma levels prior to ovarian stimulation in couples who underwent IVF/ICSI.And we…
- Conditions
- Vitamin D Deficiency, Infertility, Couples, In-vitro Fertilization
- Trial name
- NCT03305510
- Testing
- vitamin D is below 20ng/ml
- Volunteers
- 1,500 people
- Sponsor
- Tongji Hospital
Cardiovascular Autonomic Neuropathy
Risk Analysis for Cardiovascular Autonomic Neuropathy
This is a large-scale, community-based, cross-sectional study to evaluate environmental and genetic risk factors for cardiovascular autonomic neuropathy in general Chinese population.
- Trial name
- NCT02462616
- Testing
- not intervention
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Non-muscle Invasive Bladder Cancer
"En Bloc" Resection of NMIBC: a Prospective， Single Centre，Randomized Study
The traditional method of choice for intravesical resection of bladder tumors is conventional transurethral resection of bladder tumor (cTURBT).
- Trial name
- NCT03221062
- Testing
- Laser en Bloc Resection
- Volunteers
- 180 people
- Sponsor
- Tongji Hospital
Liver Carcinoma Resectable
Trans-parenchymal Compressing Suture in Major Liver Resection
Non-anatomical liver resection with appropriate resection margin was regarded as a potential curative treatment for selected major hepatic carcinoma due to preserving maximal normal liver, especially in cirrhotic patients.
- Trial name
- NCT03215290
- Testing
- TCS
- Volunteers
- 382 people
- Sponsor
- Tongji Hospital
Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes
This study is undertaken to determine if intravenous Lipo-PGE1 therapy would improve coronary microvascular perfusion in patients with ischemic heart disease by CMRI.
- Trial name
- NCT03159559
- Testing
- Lipo-PGE1
- Volunteers
- 60 people
- Sponsor
- Tongji Hospital
Sick Sinus Syndrome, Complete Atrioventricular Block
Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Double-chamber Pacemaker Implantation
This study is intended to compare the feasibility, safety and efficacy of Ensite-NavX zero-fluoroscopic navigation system to conventional fluoroscopic X-ray approach as to performing double-chamber pacemaker implantation.
- Conditions
- Sick Sinus Syndrome, Complete Atrioventricular Block, High Degree Second Degree Atrioventricular Block (Disorder), Bradycardia
- Trial name
- ZF-PMDC (NCT03118427)
- Testing
- zero-fluoroscopy 3D navigation, conventional x-ray navigation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Sick Sinus Syndrome, Complete Atrioventricular Block
Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Single-chamber Pacemaker Implantation
This study is intended to compare the feasibility, safety and efficacy of Ensite-NavX zero-fluoroscopic navigation system to conventional fluoroscopic X-ray approach as to performing single-chamber pacemaker implantation.
- Conditions
- Sick Sinus Syndrome, Complete Atrioventricular Block, High Degree Second Degree Atrioventricular Block, Bradycardia
- Trial name
- ZF-PMSC (NCT03118440)
- Testing
- zero-fluoroscopy 3D navigation, conventional x-ray navigation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Lateral Ligament Repair, Talar Cartilage Lesion
Microfracture Technique for Talar Articular Cartilage Lesions With or Without Lateral Ligament Repairment
To study the clinical efficacy of microfracture combined with lateral ligament repairment for cartilage lesions of talus through the comparison between microfracture with and without lateral ligament repairment.
- Conditions
- Lateral Ligament Repair, Talar Cartilage Lesion, Microfracture
- Trial name
- NCT03064399
- Testing
- without lateral ligament repairment, lateral ligament repairment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Postieror Malleolar Fracture, Treatment
Comparative Study of Postieror Ankle Fracture
To compare the clinical efficacy of open reduction and internal fixation (ORIF) with plate and screw for postieror malleolar fractures.
- Trial name
- NCT03064386
- Testing
- Plate fixation, Screw fixation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Ventricular Arrythmia, Ventricular Premature Complexes
Zero-fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for the Treatment of Ventricular Arrhythmias
This study is intended to compare the feasibility, safety and efficacy of a zero-fluoroscopy approach using Ensite NavX as the only imaging modality with conventional fluoroscopic approach for the catheter ablation of idiopathic…
- Conditions
- Ventricular Arrythmia, Ventricular Premature Complexes, Ventricular Tachycardia
- Trial name
- ZFOVA (NCT03041519)
- Testing
- Zero-fluoroscopy ablation, Conventional fluoroscopy ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tongji Hospital
Hypertension, Diabetes Mellitus
The Study of CCTM and Common Diseases
This study aimed to explore the associations between constitutions of traditional Chinese medicine (TCM) and common disease (CD).
- Conditions
- Hypertension, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease Moderate, Coronary Artery Disease
- Trial name
- NCT02998944
- Volunteers
- 3,748 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Surgical Blood Loss
New Techniques to Reduce Intra-operative Bleeding During Complex Liver Resection
This observational study introduced an new advanced bleeding control strategy during complex liver resection.This newly described "stepwise vascular control" technique was efficacious and feasible to control intra-operative…
- Trial name
- NCT02996006
- Testing
- stepwise vascular control
- Volunteers
- 80 people
- Sponsor
- Tongji Hospital
HDFN
Establish a Non-invasive Prenatal Genotyping and Extraction Technology to Diagnose and Treat the HDN.
To establish a genotyping and extraction technology of non invasive prenatal diagnosis for fetal blood group genotype from cell-free fetal DNA in peripheral blood of pregnant women.
- Trial name
- NCT02969174
- Testing
- zimin Lu,Guo Sa
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Cardiovascular Autonomic Neuropathy
Genetic, Environment and Its Interaction Analysis for Cardiovascular Autonomic Neuropathy
A large-scale, community-based, cross-sectional study was conducted to explore the extent to which genetic, environment and its interactions associated with cardiovascular autonomic neuropathy (CAN) in general Chinese population.
- Trial name
- NCT02461342
- Testing
- not intervention
- Where
- 2 sites in China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Diagnostic Performance of Cardiovascular Autonomic Neuropathy
Bayesian Estimation of Diagnostic Performance for Cardiovascular Autonomic Neuropathy
This study aimed to evaluate the reference values for the short-term heart rate variable (HRV), estimate the performance of cardiovascular autonomic neuropathy (CAN) diagnostic tests in the absence of a gold standard, and assess…
- Trial name
- NCT02459522
- Testing
- not intervention
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine