Clinical trials: sponsored by Tongji Hospital
Bidirectional Endoscopy
ED90 of Remimazolam Anesthesia Induction in Painless Bidirectional Endoscopy in Children
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups.
- Trial name
- ED90 (NCT06121609)
- Testing
- Remimazolam
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Tongji Hospital
Intracerebral Haemorrhage, Minimally Invasive Treatment
Stereotactic Thrombolysis With Tenecteplase for Supratentorial Intracerebral Hemorrhage
This is an phase III prospective, multi-center, open-label, randomized controlled trial (RCT) with blinded endpoint assessment. It plans to enroll 768 subjects with spontaneous supratentorial intracerebral hemorrhage, who will be…
- Trial name
- STEPS (NCT07208097)
- Testing
- Stereotactic thrombolysis with Tenecteplase
- Where
- 2 sites in China
- Volunteers
- 768 people
- Sponsor
- Tongji Hospital
Nasal Polyps
Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps
This study is designed to evaluate whether the addition of nasopharyngeal lymphoid tissue ablation to full-house endoscopic sinus surgery (ESS) provides superior control of nasal mucosa inflammation compared to full-house ESS…
- Trial name
- NCT07245329
- Testing
- Nasopharyngeal Lymphoid Tissue Ablation, Full-House Endoscopic Sinus Surgery
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Tongji Hospital
Tonsillectomy With or Without Adenoidectomy
Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy
To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy.
- Trial name
- NCT07118579
- Testing
- Remimazolam, Propofol, Ciprofol
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tongji Hospital
B-Cell Non-Hodgkin Lymphoma
A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 )
A Clinical Study to Investigate the Safety, Efficacy, and Cellular Metabolism of CT1190B CAR-T Cell therapy, in Patients with Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma.
- Trial name
- CT1190B (NCT07053670)
- Testing
- CAR T cells
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Tongji Hospital
Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis)
Intraoperative Paravertebral Block and Postoperative Complications
This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis), Pulmonary Infections, Respiratory Failure Without Hypercapnia
- Trial name
- IPVB and POCs (NCT07211529)
- Testing
- Paravertebral Block (PVB)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Breast Cancer
An In-situ Detection for MicroRNA
We designed a new in-site detection method for MicroRNA in the serum of patients with breast cancer.
- Trial name
- NCT06529614
- Testing
- In-situ detection for Micro-RNA
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Intracerebral Hemorrhage, Brain Hemorrhage
Efficacy and Safety of Calculus Bovis Sativus (CBS) for Intracerebral Hemorrhage(CBSinICH)
The most common cause of death for Chinese patients is intracerebral hemorrhage(ICH), particularly cerebral infarction. It places a heavy burden on people, families, and society as a whole and poses considerable risks of death…
- Trial name
- NCT07080632
- Testing
- Calculus bovis sativus (CBS), Natural Calculus Bovis(NCB)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Spinal Anesthesia
Impact of Real-Time Ultrasound-Guided Spinal Anesthesia Versus Landmark-Guided Spinal Anesthesia on Anesthesia Procedural Time
Intraspinal anesthesia, traceable to the late 19th century, involves injecting local anesthetics into the spinal canal to block nerve signals, relieving pain and relaxing muscles for surgery.
- Trial name
- NCT06656793
- Where
- China
- Volunteers
- 3,597 people
- Sponsor
- Tongji Hospital
Genitourinary Syndrome of Menopause (GSM)
A Clinical Study of Chinese Herbal Formula TJAOA103 in Treating Genitourinary Syndrome of Menopause
The goal of this clinical trial is to learn if Chinese herbal formula TJAOA103 works to treat genitourinary syndrome of menopause (GSM). It will also learn about the safety of TJAOA103.
- Trial name
- NCT07160127
- Testing
- TJAOA103
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Tongji Hospital
Uterine Fibroids, Female Infertility
Prospective Validation Study of a Uterine Fibroid-Related Infertility Prediction Model
Female fertility may be affected by uterine fibroids, although this association has not been elucidated. Our retrospective study has already constructed a predictive model for infertility risk in patients with uterine fibroids…
- Trial name
- NCT07177534
- Testing
- No intervention
- Volunteers
- 7,084 people
- Sponsor
- Tongji Hospital
Pulmonary Complication, Anesthesia
Spinal Versus General Anesthesia on Postoperative Pulmonary Complications
The objective of this study was to investigate the difference in postoperative pulmonary complications (PPCs) between spinal anesthesia and general anesthesia in patients undergoing delayed hip surgery.
- Conditions
- Pulmonary Complication, Anesthesia, Hip Fractures
- Trial name
- NCT06425627
- Testing
- spinal anesthesia, general anesthesia
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Tongji Hospital
ACS - Acute Coronary Syndrome
Multi-omics Characterization and Model Construction of Colchicine Anti-inflammatory Therapy Efficacy in ACS Patients
The aim of this prospective cohort study was to investigate the multi-omics characteristics of the efficacy of colchicine treatment in patients with ACS and to construct a model of efficacy.
- Trial name
- MCM-CATE-ACS (NCT07064109)
- Testing
- Colchicine 0.5 MG Oral Tablet Once Daily
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
NMO Spectrum Disorder
Monoclonal Antibody-Based Therapies for AQP4-Positive NMOSD
The primary objective of this registry study is to evaluate the therapeutic efficacy and safety profiles of distinct monoclonal antibody-based therapies for aquaporin-4 immunoglobulin G-seropositive neuromyelitis optica spectrum…
- Trial name
- NCT06885957
- Testing
- Mab Therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Crohn Disease
Prospective Cohort Establishment and Clinical Observation of Children With Crohn's Disease
To evaluate the clinical manifestations, treatment options, and improved clinical outcomeof children with Crohn's disease in real-world Settings: (1) analysis of clinical manifestations; (2) probability of using the same…
- Trial name
- CD (NCT06673134)
- Testing
- enteral nutrition, Immunotherapy, biological agents
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Hepatecellular Carcinoma, Hepatectomy
AI-Based Prediction of HCC Recurrence Patterns After Resection (APAR)
This observational study aims to validate a deep learning model for predicting aggressive recurrence patterns in patients with early-stage liver cancer (HCC) after surgery.
- Trial name
- NCT07062380
- Testing
- Curative liver resection, Real-world multimodal therapy
- Where
- China
- Volunteers
- 353 people
- Sponsor
- Tongji Hospital
Nonalcoholic Fatty Liver Disease, Metabolic-associated Fatty Liver Disease
To Explore the Value of New MR Technology in Non-invasive Quantitative Assessment of Systemic Metabolism, Disease Status and Prognosis in Patients With Metabolic-Associated Fatty Liver Disease
The purpose of this study is to explore the value of new MR technology in assessing the systemic metabolism, disease status, and prognostic risk of metabolism-related fatty liver disease.
- Trial name
- NCT07149571
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Kidney Transplant Failure and Rejection, Transplantation, Kidney
To Explore the Application Value of Magnetic Resonance Imaging in Noninvasive Quantitative Evaluation of Graft Function and Systemic Metabolism After Renal Transplantation
At present, renal biopsy is the gold standard for evaluating the pathology of renal transplants, but it is invasive and has the risk of serious complications; and the sampled tissue is only a small part of the kidney, which is…
- Conditions
- Kidney Transplant Failure and Rejection, Transplantation, Kidney, Kidney Transplant Dysfunction
- Trial name
- NCT07145944
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Cognitive Dysfunction
The Application of an AI-driven Multimodal Predictive Model for Cognitive Impairment in Patients With Type 2 Diabetes Mellitus
The objective of this observational study is to evaluate the accuracy and feasibility of an artificial intelligence-based multimodal cognitive screening system in early identification of diabetes-related mild cognitive impairment…
- Trial name
- NCT07128186
- Testing
- follow-up observation
- Where
- 21 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Elective Surgery
ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia
Exploring the 90% effective dose (ED90) of fospropofol disodium in induction and maintenance of anesthesia in adults of different ages, providing more clinical evidence for the application of fospropofol disodium in clinical…
- Trial name
- NCT06344325
- Testing
- fospropofol
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Tongji Hospital