Clinical trials: sponsored by Tulane University
Diabetes, PreDiabetes
Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial
The proposed randomized controlled trial will test the effect of a low-carbohydrate diet on hemoglobin A1c among individuals with elevated hemoglobin A1c that are within the range of prediabetes or diabetes.
- Conditions
- Diabetes, PreDiabetes, Metabolic Disease, Hyperglycemia
- Trial name
- ADEPT (NCT03675360)
- Testing
- Low-Carbohydrate Diet
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Ischemic Stroke
Intensive Blood Pressure Intervention in Stroke (IBIS) Trial
The investigators propose to conduct a multicenter randomized controlled trial to test the effect of a systolic blood pressure target of less than 120 mmHg (intensive treatment) compared to a target of less than 140 mmHg…
- Trial name
- IBIS (NCT03585595)
- Testing
- Blood pressure lowering strategy
- Sponsor
- Tulane University
Burnout, Burnout, Professional
Use of Death Cafes to Prevent Burnout in ICU Healthcare Employees
Burnout affects a significant number of healthcare employees and leads to worsened mental health, increased job turnover, and patient safety events.
- Conditions
- Burnout, Burnout, Professional, Burnout, Psychological, Anxiety
- Trial name
- STOPTHEBURN (NCT04347811)
- Testing
- Death Cafe
- Where
- 4 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Chronic Kidney Disease, Albuminuria
Sodium Lowering and Urinary Protein Reduction Trial
The proposed randomized controlled trial will test the effect of dietary sodium reduction on albuminuria in patients with proteinuric chronic kidney disease.
- Trial name
- SUPER (NCT02945969)
- Testing
- Low Sodium Diet
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Tulane University School of Public Health and Tropical Medicine
Gestational Diabetes, PreDiabetes
Maternal Health Diabetes Prevention Study
The aim of this project is to use the Exploration, Preparation, Implementation, Sustainment (EPIS) framework to collect pilot data on the implementation of a Diabetes Prevention Program-like intervention in the Women, Infants…
- Conditions
- Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
- Trial name
- NCT05343494
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tulane University
Type 2 Diabetes, Hypertension
Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
To assess the effect of sodium-glucose cotransporter 2 (SGLT-2) inhibitors on blood pressure and urinary angiotensinogen. This is a cross over study design, where 40 subjects will receive Dapagliflozin for 6 weeks followed by…
- Trial name
- NCT02796170
- Testing
- Dapagliflozin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tulane University School of Medicine
Covid19
Real World Study of COVID-19 in a Flyover Region
Real world data are needed on remdesivir (RDV) efficacy in COVID-19, especially in the underserved populations of the United States (U.S.) Gulf Coast as initial clinical trials may not be representative of this population.
- Trial name
- NCT04962347
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- Tulane University
Skin Diseases
Digital Toolkit for Skin Diseases in LMICs
To evaluate the early detection and effective management of skin diseases using the mHealth app in Cote d'Ivoire, a mixed-methods pilot trial will be conducted in Cote d'Ivoire.
- Trial name
- MIND-the-SKIN (NCT05300399)
- Testing
- mHealth app
- Where
- Côte d’Ivoire
- Volunteers
- 1,364 people
- Sponsor
- Tulane University
Hepatitis C, Atherosclerosis
Counseling Hepatitis C Virus (HCV) Positive Patients for Cardiovascular Disease Risk Factors
The study aims to compare the effect of a cardiovascular education package intervention on treatment-seeking behavioral outcomes of HCV+ patients.
- Trial name
- NCT03402334
- Testing
- Patient counseling for HCV associated CVD risk factors
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Tulane University
Relapsed Multiple Myeloma, Refractory Multiple Myeloma
Elotuzumab, Selinexor, and Dexamethasone for Relapsed Refractory Multiple Myeloma
The food and drug administration (FDA) has approved the use of Selinexor, an oral, first-in class, exportin 1 (XPO1) inhibitor, in combination with low-dose dexamethasone in patients with triple-refractory (disease refractory to…
- Trial name
- ESdRRMM (NCT05170789)
- Testing
- Elotuzumab, Selinexor, and Dexamethasone (ESd)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Cardiovascular Diseases, Cardiovascular Risk Factor
Cooking for Health Optimization With Patients
Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Nutrition Disorders, Diabetes
- Trial name
- CHOP (NCT03443635)
- Testing
- Treatment
- Where
- United States
- Volunteers
- 7,192 people, healthy volunteers welcome
- Sponsor
- Tulane University
Cancer
Intervention to Improve Caregiver Palliative Care Knowledge and Attitudes
This randomized clinical trial will assess whether a psychoeducational intervention will improve palliative care knowledge and attitudes among close friends and family members of individuals with cancer.
- Trial name
- NCT05162807
- Testing
- Psychoeducational Video on Palliative Care, Educational Video on Nutrition
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Tulane University
Chlamydia Trachomatis Infection, Gonorrhea
Check it: A New Approach to Controlling Chlamydia Transmission in Young People
This study, named "Check it," is a bundled program for African American (AA) men ages 15-24 that includes community testing for chlamydia and gonorrhea, expedited treatment for subjects who test positive and their female sexual…
- Trial name
- NCT03098329
- Testing
- Ct/GC screening
- Where
- United States
- Volunteers
- 1,907 people, healthy volunteers welcome
- Sponsor
- Tulane University
Self-regulation, Respiratory Sinus Arrhythmia
Mom Power With High-Adversity Mothers and Children
This study will evaluate whether the intervention, Mom Power, improves the self-regulation of mothers with a history of trauma and their children.
- Trial name
- MPHAMC (NCT04241913)
- Testing
- Mom Power Intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tulane University
Chronic Kidney Disease
Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial
The proposed randomized controlled trial will test the safety and efficacy of combination therapy with sodium nitrite and isoquercetin on endothelial function and inflammation among patients with chronic kidney disease.
- Trial name
- NICE (NCT02552888)
- Testing
- Immediate release sodium nitrite, Isoquercetin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Tulane University
PTSD, Post ICU Syndrome
Intensive Care Unit (ICU) Diary Project
Psychological morbidity in both patients and family members related to the intensive care unit (ICU) experience is an often overlooked, and potentially persistent, healthcare problem recognized by the Society of Critical Care…
- Trial name
- NCT04305353
- Testing
- Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tulane University School of Medicine
Dermatochalasis
Topical Bimatoprost for Chemical Blepharoplasty
Topical bimatoprost has been shown to cause periorbital changes of soft tissue which are most pronounced when used directly onto the cornea for the treatment of glaucoma.
- Trial name
- NCT02830776
- Testing
- bimatoprost 0.03% ophthalmic solution
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tulane University
Cancer
Personality and Cancer Care Study
This randomized clinical trial will test whether giving an individualized personality feedback report to adults with a history of cancer can improve their self-awareness, confidence in managing their illness, and mood.
- Trial name
- NCT04625439
- Testing
- Personality Feedback Self-Management Intervention
- Where
- United States
- Volunteers
- 419 people
- Sponsor
- Tulane University
Obesity, Type2 Diabetes
Impact of Plasma Soluble Prorenin Receptor in Obese and Type 2 Diabetic Patients
Obesity increases the risk for type 2 diabetes mellitus, high blood pressure, and mortality. Obesity is a major health problem in the United States, especially in the Deep South regions.
- Conditions
- Obesity, Type2 Diabetes, Bariatric Surgery Candidate
- Trial name
- NCT03643783
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tulane University
Pleural Infection, Empyema
Fibrinolysis Compared to Thoracoscopy for Pleural Infection
The purpose of this prospective randomized clinical trial is to compare two currently accepted standard-of-care treatment strategies: Medical thoracoscopy as compared to instillation of intrapleural tissue Plasminogen Activator…
- Conditions
- Pleural Infection, Empyema, Pleural Diseases, Parapneumonic Effusion
- Trial name
- NCT03468933
- Testing
- tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase), Medical Thoracoscopy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Tulane University