Clinical trials: sponsored by Turku University Hospital
Otitis Media
Family MobilePhone Otoscopy in Diagnostics of Otitis Media
This is a one-center clinical study carried out in Turku, Finland. The study patients will be randomly allocated to one of the two parallel study groups (teaching group and control group).
- Trial name
- FamilymOTO (NCT02452164)
- Testing
- Teaching, (CellScopeOTO)
- Where
- Finland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Hip Fracture
Troponin Elevation in Consecutive Patients With Hip Fracture
The aims of this study is to study the occurrence of the troponin elevations, ECG changes, and cardiac symptoms in unselected consecutive patients with hip fracture. Followup will be carried out up to one year period.
- Trial name
- NCT01015105
- Testing
- observation
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Prostate Carcinoma
Preoperative Staging and Dose Escalated Radiotherapy of Prostate Carcinoma With PET and MRI
Prostate cancer (PCa) is currently the most common neoplastic disease among men in well-developed countries with 350 000 new cases diagnosed annually in Europe and 4 800 in Finland.
- Trial name
- Flucipro (NCT02002455)
- Testing
- PET/CT, PET/MRI, mpMRI
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- Turku University Hospital
Urinary Incontinence, Quality of Life
Pelvic Floor Symptoms and Quality of Life in Elderly Women - a Population-based Pilot Study
To assess pelvic floor symptoms and quality of life in elderly women.
- Trial name
- NCT02338726
- Testing
- Gynecological examination
- Where
- Finland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Prostate Cancer
Development and Validation of Novel MRI Methods for the Detection of Prostate Cancer Aggressiveness
The purpose of this study is to develop, validate, and evaluate the correlation of novel magnetic resonance imaging (MRI) methods with prostate cancer aggressiveness and histological data obtained during prostatectomy.
- Trial name
- PROAG (NCT02545881)
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Tinnitus
Tinnitus rTMS 2013
Tinnitus is the perception of sound in the absence of corresponding external sound. Tinnitus affects approximately 10-15 % of the population.
- Trial name
- NCT01929837
- Testing
- E-fied navigated rTMS, non-navigated rTMS, Navigated rTMS
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Sternotomy Wound
Wound Inflammatory Cells After Cardiac Surgery
One hundred patients, aged from 41 to 78 years, underwent open heart surgery in the years 1998-1999 and were studied by using the Cellstick device for harvesting wound inflammatory cells during the first 24 hours after surgery.
- Trial name
- NCT02875509
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Prostate Cancer
Improved Prostate Cancer Diagnosis - Combination of Rapid Prebiopsy Magnetic Resonance Imaging and Biomarkers
This study will enroll 200 men with clinical suspicion of prostate cancer due to higher serum level of PSA than 2.5 ng/ml or abnormal digital rectal examination.
- Trial name
- IMPROD2_0 (NCT02844829)
- Testing
- Prostate MRI
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Rhinovirus Infection
Clinical and Virological Efficacy of Pegylated Interferon Alpha in the Treatment of Rhinovirus Infection in Patients With Primary Hypogammaglobulinemia: Randomized Controlled Trial
The study will investigate the efficacy and safety of subcutaneous interferon alpha -2a to eradicate rhinovirus in patients with primary hypogammaglobulinemia.
- Trial name
- Hypogamma Int1 (NCT02661477)
- Testing
- pegylated interferon alfa 2
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Healthy
Tonsillar Cytokine Expression After Allergen and/or Virus Intervention
Hypotheses 1. Immunotherapy induces tolerogenic effects to allergens in T cell regulation in tonsils. 2. Influenza vaccination induces a strong interferon response and decreases Th2 response in tonsils. 3.
- Trial name
- Tons2 (NCT01924208)
- Testing
- Timothy, Phleum pretense, Live attenuated influenza virus, Timothy + attenuated influenza virus
- Where
- 4 sites in Finland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Maternal-Fetal Relations, Muscle Weakness
Developmental ORIgins of Healthy and Unhealthy AgeiNg: the Role of Maternal Obesity
The prevalence of obesity in the developed world has increased markedly over the last 20 years. Considering the prevalence of obese and overweight adult subjects, and the fact that pregnancy itself induces a state of insulin…
- Conditions
- Maternal-Fetal Relations, Muscle Weakness, Insulin Resistance
- Trial name
- DORIAN (NCT01931540)
- Testing
- Exercise Training
- Where
- 2 sites in Finland
- Volunteers
- 48 people
- Sponsor
- Turku University Hospital
Prostate Cancer
Improved Prostate Cancer Diagnosis - Combination of Magnetic Resonance Imaging and Biomarkers
Prostate cancer has been the most common cancer in men in Finland over the last ten years. Prostate-specific antigen (PSA) plays an important role in screening of prostate cancer.
- Trial name
- IMPROD (NCT01864135)
- Testing
- 3T MRI (Magnetom Verio 3T, Erlangen, Germany), Transrectal ultrasound (Bk Medical Pro Focus Ultraview 2202 system)
- Where
- Finland
- Volunteers
- 175 people
- Sponsor
- Turku University Hospital
Diagnosis
Nonfunctional Pancreatic NET and PET Imaging
Predicting aggressive behavior in the group of nonfunctional pancreatic neuroendocrine tumors (NF P-NET) remains a difficult problem in clinical practice.
- Trial name
- NCT02621541
- Testing
- PET/CT
- Where
- 2 sites in Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Ankle Sprain
Validation of the Foot and Ankle Ability Measure Tool in Finnish
The purpose of this study is to validate the Foot and Ankle Ability Measure in Finnish.
- Trial name
- FAAM-Fi (NCT02330198)
- Where
- Finland
- Volunteers
- 84 people
- Sponsor
- Turku University Hospital
Healthy
68Ga-Citrate PET of Healthy Volunteers
This study investigates whole-body distribution kinetics of intravenously administered Gallium-69 (68Ga) citrate by positron emission tomography (PET)/computed tomography (CT).
- Trial name
- SITRAT (NCT01951300)
- Testing
- Gallium-68 citrate
- Where
- Finland
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Egg Allergy, Cow's Milk Allergy
Cow's Milk and Hen's Egg Hyposensitization in Adults
Egg, milk and cereal allergies are the most important food allergies in Finnish children, the prevalence in western countries is 1-4 %. In some individuals food-allergy is maintained in to adulthood.
- Trial name
- NCT02083471
- Testing
- Specific Oral Tolerance Induction with Egg or Cow's milk
- Volunteers
- 40 people
- Sponsor
- Turku University Hospital
Insulin Sensitivity, Type 2 Diabetes
Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes
The objectives of this study are to compare the effects of rosiglitazone and metformin on insulin stimulated glucose uptake in subjects with type 2 diabetes.
- Trial name
- ROSI (NCT02526615)
- Testing
- Rosiglitazone, Metformin
- Where
- 3 sites in Finland
- Volunteers
- 48 people
- Sponsor
- Turku University Hospital
Sleep Apnea
Telemonitoring in CPAP Treatment
Wireless telemonitoring was used during the habituation phase of continuous positive airway pressure (CPAP) treatment in obstructive sleep apnoea (OSA) patients.
- Trial name
- TeleCPAP (NCT02509247)
- Testing
- Telemonitoring
- Where
- Finland
- Volunteers
- 111 people
- Sponsor
- Turku University Hospital
Traumatic Brain Injury
Evidence Based Diagnostics and Treatment Planning Solution for Traumatic Brain Injuries
Adult patients, age ≥ 18 years, with clinically diagnosed mild, moderate or severe brain trauma will be asked to participate in the study.
- Trial name
- NCT02021877
- Where
- 2 sites in Finland, United Kingdom
- Volunteers
- 396 people
- Sponsor
- Turku University Hospital
Female Genital Prolapse
Single Incision Transvaginal Mesh in Treatment of Posterior Vaginal Wall Prolapse
Definition: To find out complications, objective and subjective outcomes of patients with symptomatic posterior vaginal wall prolapse undergoing posterior mesh operation in nine Finnish hospitals during September 2010 and August…
- Trial name
- NCT02092623
- Testing
- Transvaginal posterior mesh
- Where
- Finland
- Volunteers
- 111 people
- Sponsor
- Turku University Hospital