Clinical trials: sponsored by Turku University Hospital
Cancer Survivor
Fit for Everyday Life - Increasing Exercise and Physical Activity in Those Rehablilitating From Cancer
The aim of the study is to increase the physical activity and exercise of those recovering from cancer (after treatments) and to promote a functional return to everyday life and coping in everyday life.
- Trial name
- NCT05403671
- Testing
- Increasing Exercise and Physical Activity in Those Rehablilitating From Cancer
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Adolescent Idiopathic Scoliosis
CLOSED SUCTION DRAIN VS. NO DRAIN IN ADOLESCENTS UNDERGOING PEDICLE SCREW INSTRUMENTATION FOR IDIOPATHIC SCOLIOSIS (DAISY 2018). A Randomized Clinical Trial
Abstract Background - Closed suction drain is typically used worldwide after instrumented posterior spinal fusion for adolescent idiopathic scoliosis (AIS).
- Trial name
- DAISY 2018 (NCT03729947)
- Testing
- Subfascial closed suction drain
- Where
- 3 sites in Finland, Sweden
- Volunteers
- 90 people
- Sponsor
- Turku University Hospital
Pharmacokinetics, Arthritis Knee
Bioavailability of Intranasal Dexmedetomidine
Aim of this study is to characterize the pharmacokinetics of dexmedetomidine in supine, anesthetized adult patients after intranasal dosing.
- Conditions
- Pharmacokinetics, Arthritis Knee, Arthritis of Hip, Anesthesia
- Trial name
- INDEX (NCT05065775)
- Testing
- Dexmedetomidine
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Sleep Apnea
Sleep-disordered Breathing in Postmenopausal Women
The purpose of this study is to investigate the effectiveness of CPAP treatment to co-morbidities of sleep apnea by looking the change of the consumption of medication of the co-morbidities before and after starting the CPAP…
- Trial name
- NCT01825291
- Testing
- CPAP treatment
- Volunteers
- 800 people
- Sponsor
- Turku University Hospital
High Risk Prostate Cancer
Novel Imaging in Staging of Primary Prostate Cancer
Prostate cancer (PC) is the most common cancer among men and one quarter of diagnosed PC are metastatic at the time of diagnosis.
- Trial name
- PROSTAGE (NCT03537391)
- Testing
- Whole body contrast enhanced computer tomography, 99mTC-HMDP planar bone scintigraphy (BS), 99mTc-HMDP single photon emission computer tomography/computer tomography
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Preterm Birth, Development Delay
Evaluation of Digital Follow up of Preterm Infants
The aim is to study how a digital follow up tool can identify the preterm born children and their families who need further support or clinical interventions
- Conditions
- Preterm Birth, Development Delay, Sensory Disorder, Growth Disorders
- Trial name
- ePIPARI (NCT05238168)
- Testing
- ePIPARI digital follow up tool
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Turku University Hospital
Surgical Wound Infection
Relation of Skin Closure Method to Groin Wound Infections After Proximal Femoral Artery Exposure.
This study aims to asses whether the rate of surgical wound infections in vascular surgery procedures involving exposure of the proximal femoral artery can be reduced using a different skin closure technique.
- Trial name
- NCT03468621
- Testing
- Wound closure
- Where
- 3 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Neck Abscess
Dual-Energy Computed Tomography (DECT) in Acute Neck Infections: Comparison With Magnetic Resonance Imaging (MRI)
The purpose of this prospective study is to compare MRI and DECT in imaging acute neck infection. 50 patients suspected for neck infection will undergo both modalities, which will then be compared in terms of depiction of edema…
- Trial name
- ANI-DECT (NCT05303922)
- Testing
- Dual-energy CT, MRI
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Coronary Artery Disease
68Ga-NODAGA-RGD PET in Patients With an Occluded Coronary Artery
Background: In patients with coronary artery disease, acute or chronic coronary artery occlusion is associated with various degrees of ischemic myocardial injury and left ventricle dysfunction.
- Trial name
- RGDHeart (NCT04871217)
- Testing
- 68Ga-NODAGA-RGD PET-imaging
- Where
- 3 sites in Finland, Netherlands and 1 more
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Appendicitis, Other and Unspecified Acute Appendicitis
The Optimization of a Low-dose CT Protocol in Patients With Suspected Uncomplicated Acute Appendicitis and BMI >30
This study focuses on the use of contrast enhanced low-dose CT imaging as a modality to differentiate between uncomplicated and complicated acute appendicitis.
- Conditions
- Appendicitis, Other and Unspecified Acute Appendicitis, Acute Disease, Gastrointestinal Disease
- Trial name
- OPTICAP>30 (NCT04519086)
- Testing
- Low-dose CT, Laparoscopic appendectomy
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Head and Neck Cancer
Measurement of Head and Neck Tumor Hypoxia With PET-MRI
This study is designed to evaluate the performance of advanced magnetic resonance (MR) imaging in the assessment of tumor hypoxia using [18F]EF5 positron emission tomography (PET) as a reference in head and neck cancer patients.
- Trial name
- EF5NECK (NCT05246475)
- Testing
- PET-MRI
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Stroke
Effect of Daily Music Listening on Stroke Recovery
Single blind randomized clinical trial including 50 stroke patients to investigate the effect of daily music listening on behavioral, neural and physiological recovery.
- Trial name
- MUKU2 (NCT01749709)
- Testing
- Music listening, Audiobook listening
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Type 1 Diabetes
Glucose-stimulated Pancreatic Islet and Intestinal Blood Flow in Healthy Subjects and in Type 1 Diabetes
Type 1 diabetes is the major type of diabetes in the young. The pathophysiology still needs clarification in order to reach feasible means of preventing the disease.
- Trial name
- ISLET-PET (NCT02547337)
- Where
- Finland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity
Neuromolecular Risk Factors for Obesity (PROSPECT)
The goal of this project is to characterize the neural and psychological mechanisms that contribute to development of obesity in the early adulthood.
- Trial name
- NCT03106688
- Testing
- fMRI imaging, [11C]carfentanil PET scan, [18F]FMPEP-d2 PET scan
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Prostate Cancer
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis
The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low.
- Trial name
- multiIMPROD2 (NCT04287088)
- Testing
- A shared decision making
- Where
- 4 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Turku University Hospital
Advanced Cardiac Life Support
Implementation of Pit Crew Resuscitation Model on the Training of Advanced Life Support: a Randomized Controlled Study
In this study, a pit crew model is implemented in advanced life support (ALS) simulation training to student groups. The hypothesis is that the tactic model could help to maintain the CPR skills during the six month follow-up…
- Trial name
- NCT04364529
- Testing
- The pit crew model
- Where
- Finland
- Volunteers
- 104 people
- Sponsor
- Turku University Hospital
Infection, Vasculitis
Positron Emission Tomography of Infection and Vasculitis
The purpose of this study is to evaluate the value of positron emission tomography/computed tomography in various inflammatory conditions caused by bacterial infection or vasculitis.
- Trial name
- PETU (NCT01878721)
- Testing
- PET/CT
- Where
- Finland
- Volunteers
- 117 people
- Sponsor
- Turku University Hospital
Type 2 Diabetes, Obesity
Splanchnic Blood Redistribution After Incretin Hormone Infusion and Obesity Surgery
Obesity is a worldwide problem and leads to multiple metabolic and endocrinological problems. Bariatric surgeries are a growing field as a treatment choice for morbid obesity (BMI > 35 kg/m2).
- Trial name
- GIP-PET (NCT01880827)
- Testing
- Roux-en-Y, GIP-infusion, GLP-1
- Where
- Finland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Obesity, Morbid, Insulin Resistance
Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, Insulin Resistance and Central Reward System
Background: Morbid obesity is associated with decreased brain µ-opioid receptor availability, possibly resulting in higher food intake needed to gain pleasure from eating.
- Trial name
- BariBrainPET (NCT05080205)
- Testing
- Bariatric surgery
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Morbid Obesity
Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, and Activation of Central Reward System
Background: The investigators have found that obesity and insulin resistance result in significantly increased brain insulin-stimulated glucose uptake, whereas in every other tissue glucose uptake is lower in the obese compared…
- Trial name
- BARIBRAIN (NCT04343469)
- Testing
- Bariatric Surgery (RYGB or LSG)
- Where
- 2 sites in Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital