Clinical trials: sponsored by Umeå University
Stroke, Fatigue
Does Cardiorespiratory Interval Training Improve Post-stroke Fatigue
Post-stroke fatigue is common and negatively influences post-stroke recovery. Today, there is insufficient evidence how to treatment post-stroke fatigue.
- Trial name
- NCT03458884
- Testing
- Cardiorespiratory interval training
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Dermatoses, Vestibulodynia
Treatment and Mapping of Impostor Phenomenon
The aim of this study is to evaluate persons/patients with different skin diseases or pain to evaluate whether unhealthy perfectionism, stress, anxiety, impostor phenomenon (inability to realistically assess your competence and…
- Conditions
- Dermatoses, Vestibulodynia, Hyperhidrosis, Pain Syndrome
- Trial name
- NCT05805696
- Testing
- Impostor tasks
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Velopharyngeal Insufficiency in Children With Isolated or Combined Cleft Palate
Prospective Evaluation of Speech Function Through Patient- and Parent-response Outcome Measurements in Velopharyngeal Insufficiency
Cleft lip and/or palate (CL/P) is the most common congenital malformation, with about one in 500 children born with CL/P in Sweden, corresponding to approximately 175 births annually.
- Trial name
- NCT05838261
- Testing
- Pharyngeal flap
- Where
- 6 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Prophylactic Mastectomy
Prophylactic Mastectomy: Prospective Evaluation of the Correlation Between Skin Flap Thickness, Residual Glandular Tissue and Skin Necrosis by Imaging and Clinical Examination
Breast cancer is the most common form of cancer among women. Five to ten percent of all breast cancers are due to hereditary factors, with pathogenic variants in the breast cancer genes BRCA1/2 accounting for 2-5% of all breast…
- Trial name
- NCT05162677
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Umeå University
Prostatic Neoplasms, Lymphatic Metastasis
Dose Escalation With SIB to Intraprostatic/Lymphatic GTV in High Risk Prostate Cancer
A single arm phase 2 study to study the outcome of dose-escalation with simultaneous integrated boost to intraprostatic lesion and positive lymph nodes.
- Trial name
- PARAPLY-1 (NCT01962324)
- Testing
- SIB Dose-Escalation Radiotherapy
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Umeå University
Prostate Cancer, Radiotherapy Side Effect
Different Fractionation Schedules of Radiotherapy to the Primary Tumour in Metastatic Hormone Sensitive Prostate Cancer
de Novo metastatic prostate cancer with limited metastatic spread benefits from local radiotherapy to the prostate. Two different fractionation schedules will be tested.
- Conditions
- Prostate Cancer, Radiotherapy Side Effect, Metastatic Cancer
- Trial name
- Hypo-M1 (NCT04612907)
- Testing
- Moderate hypo-fractionation, Ultra-hypo-fractionation
- Where
- Sweden
- Volunteers
- 420 people
- Sponsor
- Umeå University
Colon Cancer, Physical Activity
Physical Activity and Its Impact on Colon Cancer Surgery
This is a prospective clinical study that studies how the physical activity level before operation of colon cancer affects the outcome of complication and histology.
- Trial name
- PACOS (NCT03947840)
- Testing
- Physical activity
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Umeå University
Post-Dural Puncture Headache
Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache
To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement…
- Trial name
- PDPH (NCT06253754)
- Testing
- MRI examination
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Umeå University
Staff and Older Persons With Home Care Service
The Effects and Meaning of a Person-centred and Health-promoting Intervention in Home Care Services
Current home care service are to a large extent task oriented with a limited focus on care recipient's involvement. Furthermore, studies have shown that low care recipients' involvement might decrease older people's quality of…
- Trial name
- NCT02846246
- Testing
- Person-centred and health-promoting home care service, Care as usual
- Volunteers
- 81 people
- Sponsor
- Umeå University
Postoperative Respiratory Complications
Effect of Speaking Aloud After Abdominal Surgery.
Hypoxia and reduced vital capacity is commonly occurring after abdominal surgery. Positive expiratory pressure is one treatment suggested to improve lung function after surgery.
- Trial name
- NCT04276584
- Testing
- Positive expiratory pressure, Speaking loudly during about 3 minutes
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Depression, Anxiety
TARA for Medical Students, a Single-arm Mixed Methods Pilot Study
Medical students have higher risks for depression, anxiety, burnout and suicide than the general population and they rarely seek professional help or treatment.
- Conditions
- Depression, Anxiety, Stress-related Problem
- Trial name
- TARA (NCT05059392)
- Testing
- Training for Awareness, Resilience and Action (TARA)
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Umeå University
Squamous Carcinoma, Head and Neck Cancer
Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer
The study's aim is to define imaging and molecular bio-markers for prediction of radiotherapy response of squamous cell carcinomas, in an early treatment phase.
- Conditions
- Squamous Carcinoma, Head and Neck Cancer, Anal Cancer, Lung Cancer
- Trial name
- MORRIS (NCT02379039)
- Where
- Sweden
- Volunteers
- 118 people
- Sponsor
- Umeå University
Keratoconus, Corneal Crosslinking
Epi-on PiXL for the Treatment of Progressive Keratoconus.
The purpose of this study is to evaluate the efficacy, safety and postoperative ocular discomfort by individually customized Photorefractive intrastromal crosslinking (PiXL) without epithelium debridement in high oxygen…
- Conditions
- Keratoconus, Corneal Crosslinking, Corneal Densitometry, Scheimpflug Photography
- Trial name
- NCT04668924
- Testing
- Epi-on PiXL in high oxygen
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Umeå University
Myopia, Refractive Errors
PiXL as a Treatment for Low Grade Myopia
To assess the improvement in myopia with phototherapeutic intrastromal corneal collagen cross-linking (PiXL) without epithelial debridement (epi-on) in high oxygen environment for low grade myopia.
- Trial name
- NCT04663048
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Umeå University
Osteoarthritis, Hip
A Comparative Study of Stem and Cup Fixation and Polyethylene Wear
A randomized controlled study comparing two types of cementless femoral stems (LCU and Corail) and two types of acetabular components (DeltaTT and Pinnacle Duofix) in primary total hip arthroplasty.
- Trial name
- NCT04064723
- Testing
- Randomization between prosthetic components
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Umeå University
Infant Formula
Growth, Allergy and Neurodevelopment in Infants on Hydrolysed Formula
Breastfeeding is the recommended diet for all infants during the first half of infancy and is associated with numerous health benefits.
- Trial name
- GRANDIOSA (NCT05578716)
- Testing
- Partially hydrolysed formula
- Where
- 2 sites in Sweden
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Umeå University
Osteoarthritis, Hip
Clinical Investigation Comparing Two Different Ultra-porous Coated Surfaces of Uncemented Cups
A randomised controlled study comparing two types of ultra-porous coated uncemented cups in total hip arthroplasty. Primary objective is to investigate if the clinical, radiological and patient-reported outcome of the new…
- Trial name
- NCT05773261
- Testing
- MobilLINK TrabecuLINK cup, Pinnacle Gription cup
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Pulmonary Disease, Chronic Obstructive
Increase Level of Physical Activity and Decrease Use of Health Care for People With COPD
This study evaluates the effects of the COPD Web (KOLwebben), an interactive web-based tool directed towards people with chronic obstructive pulmonary disease (COPD).
- Trial name
- COPD (NCT03746873)
- Testing
- COPD Web
- Where
- Sweden
- Volunteers
- 146 people
- Sponsor
- Umeå University
Hypertension,Essential, Lifestyle-related Condition
The Föllinge Hypertension and Lifestyle Study
Ambulatory blood pressure measurement is more demanding in terms of technical equipment and specially trained staff. If blood pressure measurement in a self-care room is on average equivalent to the ambulatory blood pressure…
- Trial name
- FIHST (NCT04488289)
- Testing
- Lifestyle
- Where
- Sweden
- Volunteers
- 117 people
- Sponsor
- Umeå University
Echocardiography, Hip Fractures
Preoperative Focused Cardiac Ultrasound in Hip Fracture Surgery (PrEcho)
The primary objective of this study is to investigate the impact of preoperative focused transthoracic ultrasound (FOCUS) on intraoperative hypotension and postoperative complications in hip fracture surgery.
- Conditions
- Echocardiography, Hip Fractures, Risk Assessment, Anesthesia
- Trial name
- PrEcho (NCT05862493)
- Testing
- FOCUS echocardiography
- Volunteers
- 100 people
- Sponsor
- Umeå University