Clinical trials: sponsored by University Ghent
Apical Periodontitis, Post Operative Pain, Acute
Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation
When a tooth's nerve dies, inflammation can develop at the tip of the tooth's root. Root canal treatment is carried out to allow this inflammation to heal.
- Trial name
- NCT07883486
- Testing
- sonically activated irrigation, laser activated irrigation, conventional needle irrigation
- Where
- 2 sites in Belgium
- Volunteers
- 183 people
- Sponsor
- University Ghent
Healthy
Reject Analysis of Periapical Radiographs of Dental Implants.
Periapical radiographs of dental implants, acquired as part of two ongoing research projects, will be retrospectively analyzed using a newly developed image quality scoring form.
- Trial name
- RA1-2025 (NCT07876687)
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Parkinson Disease (PD), Cognition
Short Term Effects of a Multimodal Intervention With RGM on Cognition in People With Parkinson's Disease.
The goal of this clinical trial is to learn if the Ronnie Gardiner Method (RGM) works to improve cognitive functions in adults with Parkinson's disease (early to mid-stage).
- Conditions
- Parkinson Disease (PD), Cognition, Quality of Life, Functional Mobility
- Trial name
- NCT07863219
- Testing
- Ronnie Gardiner Method
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Ghent
Retirement
Needs Assessment Regarding "Mental Well-being-enhancing" Programs for Soon-to-be and (Recently) Retired Individuals
This study aims to improve understanding of the needs and well-being of individuals during the transition to retirement. The researchers seek to explore which activities and forms of support are perceived as helpful, which are…
- Trial name
- NCT07630285
- Testing
- No intervention (observational study)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Ghent
Suicide, Suicidal Ideation and Behavior
Pilot Study on Follow-Up of (Acutely) Suicidal Individuals From the Flemish Suicide Helpline
This pilot study aims to assess the acceptance, feasibility, and added value of follow-up calls at the suicide helpline, Zelfmoordlijn 1813, in Flanders (Belgium).
- Conditions
- Suicide, Suicidal Ideation and Behavior, Crisis Intervention
- Trial name
- CONT-1813 (NCT07343258)
- Testing
- Callbacks from the Zelfmoordlijn 1813
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide, Suicidal Ideation
Get Out of Your Head 2.0: Evaluation of an Online Prevention Campaign and Updated Website for Men
The primary objective of this study is to evaluate the perceptions and evaluations of men with suicidal thoughts, regarding the new "Get Out of Your Head" campaign and the updated website.
- Trial name
- NCT06810674
- Testing
- Get out of your head campaign and website 2.0
- Where
- Belgium
- Sponsor
- University Ghent
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Return to Sport, Shoulder Dislocation or Subluxation
Validation of an Upper Extremity Physical Performance Test Battery in Patients After Shoulder Dislocation
The goal of this exploratory prospective study is to determine if an upper extremity test battery, comprised of physical performance tests, analytical tests and patient-reported outcome measures, can predict successful return to…
- Trial name
- VAL_PPT_P (NCT07115225)
- Testing
- Analytical test - Shoulder Range of Motion (ROM), Analytical test - Shoulder Strength, Modified-Athletic Shoulder Test (M-AST)
- Where
- 2 sites in Belgium
- Volunteers
- 129 people
- Sponsor
- University Ghent
Orofacial Myofunctional Disorders, Anterior Open Bite Malocclusion
Oral Myofunctional Pattern in Children With Anterior Open Bite
Oral myofunctional disorders (OMD) are a key, internationally acknowledged environmental factor causing dental and skeletal malocclusion.
- Trial name
- OMBIT (NCT07045779)
- Testing
- Orofacial myofunctional therapy - traditional, Orofacial myofunctional therapy - reduced, Vocal warm up
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- University Ghent
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
Hearing Loss, Age-Related, Hearing Aids
Communication Training in Hearing Aid Users
The objective of the current research project is to investigate the effectiveness of communication training in first-time hearing aid users with mild to moderate hearing loss delivered in-person in groups or individually.
- Conditions
- Hearing Loss, Age-Related, Hearing Aids, Sensorineural Hearing Loss, Speech Intelligibility
- Trial name
- NCT07798453
- Testing
- Cognitive screening, Audiological Assessment, Questionnaires
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University Ghent
Cleft Lip and Palate, Cleft Palate Children
Perceptions of High and Low Intensity Speech Intervention in Children With a Cleft Palate
A cleft (lip and) palate is the most common congenital abnormality of the face and skull with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance.
- Conditions
- Cleft Lip and Palate, Cleft Palate Children, Speech Therapy, Speech Disorders in Children
- Trial name
- NCT07781566
- Testing
- High-intensity speech therapy for children with cleft palate, Low-intensity speech therapy for children with cleft palate
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University Ghent
Speech Therapy, Speech Disorders in Children
High-intensity vs Low-intensity Speech Intervention in Children With Phonological Speech Sound Disorders
Achieving speech that is understandable and acceptable to others is the key outcome in the treatment of phonological speech sound disorders. Therefore, speech therapy provided by a speech-language pathologist is essential.
- Conditions
- Speech Therapy, Speech Disorders in Children, Phonological (Speech) Disorder
- Trial name
- NCT07779759
- Testing
- High-intensity combined phonetic-phonological intervention, Low-intensity combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Ghent
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Tension-Type Headache, Cervicogenic Headache
The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.
This project comprises two studies; a cross-sectional study and a randomized controlled trial. 1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH)…
- Conditions
- Tension-Type Headache, Cervicogenic Headache, Myofascial Headache
- Trial name
- COMPHAS_RCT (NCT06100588)
- Testing
- Dry Needling, Manual therapy
- Where
- Belgium
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University Ghent
Insulin Resistance, Insulin Resistance and Type 2 Diabetes
The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk
Insulin resistance is an early etiological factor in the development of type-2 diabetes (T2D), which constitutes a large societal health burden with an expected additional rise in the years to come.
- Conditions
- Insulin Resistance, Insulin Resistance and Type 2 Diabetes, Cardiometabolic Risk Factors, Physical Activity
- Trial name
- MUSCLE MONITOR (NCT07678736)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Ghent
Suicidal Ideation, Suicide Prevention
User Evaluation Think Life
This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts.
- Conditions
- Suicidal Ideation, Suicide Prevention, mHealth Intervention
- Trial name
- NCT07654127
- Testing
- Self-help course Think Life
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy
Optimizing Combined Physical and Cognitive Activity in Community-Dwelling Older Adults.
This laboratory-based interventional study aims to determine which combination of physical activity intensity and cognitive activity difficulty yields the greatest acute cognitive benefits in community-dwelling older adults.
- Trial name
- CONSCIOUS (NCT07630272)
- Testing
- Light physical activity + easy cognitive activity, Light physical activity + challenging cognitive activity, Moderate physical activity + easy cognitive activity
- Where
- Belgium
- Volunteers
- 53 people
- Sponsor
- University Ghent
Difference Between Coastal and Inland Populations
The Coastal Exposome: a Study of Sea Air Inhalation and Possible Links to Health
The research aims to understand oceans as crucial contributors to human health in coastal environments. Oceans produce marine spray aerosols that contain a mixture of microbiota and natural biological molecules (biogenics).
- Trial name
- NCT06477627
- Testing
- no intervention
- Where
- Belgium
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Ghent
Wound Complication, Wound Care
Using WoundPilot to Support Wound Care Decisions in Patients With Chronic Wounds
This study evaluates whether a digital decision support tool, called WoundPilot, can help primary care nurses make more accurate and consistent decisions when caring for patients with chronic wounds.
- Conditions
- Wound Complication, Wound Care, Wound and Injuries
- Trial name
- NCT07562269
- Testing
- WoundPilot
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent