Clinical trials: sponsored by University Hospital, Angers
Thoracic Surgery
Erector Spinae Block in First Rib Resection: a Monocentric Before-after Study
First rib resection surgery for thoracic outlet syndrome is associated with an intense postoperative pain. It leads to significant consumption of nonsteroidal anti-inflammatory drugs and opioids, and hospitalization for several…
- Trial name
- MERCOTE (NCT04167046)
- Testing
- Erector spinae block
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Permanent Atrial Fibrillation, Venous Thrombosis
Vascular CalcIfiCation and sTiffness Induced by ORal antIcoAgulation
The VICTORIA Study (Vascular CalcIfiCation and sTiffness induced by ORal antIcoAgulation) is a comparative, parallel, prospective, controlled and randomized study of the structural and functional impact of rivaroxaban versus…
- Conditions
- Permanent Atrial Fibrillation, Venous Thrombosis, Pulmonary Embolism, Anticoagulation Treatment at Least > or = to 12-month
- Trial name
- VICTORIA (NCT02161965)
- Testing
- Rivaroxaban, Fluindione, Warfarin
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Angers
Venous Insufficiency
VEINEX : Venous Investigations During Exercise
Successfully develop and confirm with the Higher School of Electronics West Plethysmographic a multichannel recorder to perform measurements staggered volume of the lower limbs at rest, walking and recovery (6 storied measures on…
- Trial name
- VEINEX (NCT02689557)
- Testing
- plethysmography
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Surgery
Translation and Validation of the French Quality of Recovery (QoR-15) Questionnaire - Postoperative Recovery Assessment Questionnaire
Surgery (under general anaesthesia or under loco-regional anaesthesia) is an event that causes stress, anxiety, pain and even minor complications such as nausea or vomiting.
- Trial name
- FQoR-15 (NCT03967821)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 375 people
- Sponsor
- University Hospital, Angers
Vascular Diseases
Locally Applied Pressure-induced Vasodilatation
Measure microcirculatory responses after localized ischemia obtained by local application of pressure (laser speckle).
- Trial name
- LAV (NCT02861924)
- Testing
- microcirculatory responses
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Healthy Volunteers
Global Positioning Satellite and Accelerometry to Assess Human Locomotion (ACTI GPS)
The aim of the study is to validate the association of the GPS and accelerometer tools in order to assess the humain locomotion during exercises. The hypotheses are: 1.
- Trial name
- ActiGPS (NCT01805219)
- Testing
- GPS and accelerometer recording (s) during exercises
- Where
- France
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Solid Tumor, Tumor Angiogenesis
Vascular Dysfunction and Antiangiogenic Therapy
project is a pilot prospective, longitudinal, before-after, open label multicentric study.
- Conditions
- Solid Tumor, Tumor Angiogenesis, Endothelial Dysfunction, CML (Chronic Myelogenous Leukemia)
- Trial name
- DYVA-AAGG (NCT02161978)
- Where
- France
- Volunteers
- 93 people
- Sponsor
- University Hospital, Angers
Pulmonary Surgery
Erector Spinae Block, Epidural Analgesia and Intrathecal Analgesia in Thoracic Surgery
Pulmonary thoracic surgery is often responsible for severe postoperative pain, which is associated with an increase in postoperative morbidity and mortality.
- Trial name
- SPIRIT (NCT04147754)
- Testing
- Epidural anesthesia, Intrathecal morphine, Erector spinae block
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Pulmonary Embolism
Hospitalization or Out-treatment ManagEment of Patients With Pulmonary Embolism: a Randomized Controlled Trial
Several studies have demonstrated the possibility of outpatient management or early discharge for certain patients presenting acute pulmonary embolism (PE), providing a suitable structure is in place.
- Trial name
- HOME-PE (NCT02811237)
- Testing
- HESTIA, sPESI
- Where
- 28 sites in Belgium, France and 3 more
- Volunteers
- 1,975 people
- Sponsor
- University Hospital, Angers
First Trimester Abortion, Surgical Abortion
Impact of Music Intervention on Pain Control In First Trimester Surgical Abortion Under Local Anesthesia
A surgical abortion under local anesthesia is potentially painful. A protocol using analgetic is systematically used. Also the protocol is relevant , the question of taking care of the pain in a safe manner remains.
- Conditions
- First Trimester Abortion, Surgical Abortion, Music Intervention, Local Anesthesia
- Trial name
- AlgoMusic (NCT02922504)
- Testing
- Music intervention group, Controlled group
- Volunteers
- 159 people
- Sponsor
- University Hospital, Angers
Simulation Training, IVf
Benefits of an Oocyte Pickup Simulation Training Program
The primary objective of this study was to evaluate oocyte pick up simulation training program for teaching residents. The secondary objectives were to evaluate resident satisfaction and the overall current state of oocyte pick…
- Conditions
- Simulation Training, IVf, Education
- Trial name
- NCT04130139
- Testing
- oocyte pick up simulator
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Patient Satisfaction, Neurocognitive Disorders
COgilus Remediation in Alzheimer Patients (CORA)
This study evaluates the usability of a new tablet PC application to stimulate cognitive functions. Patients hospitalized in a geriatric ward (day or complete hospitalisation) but also their informal and professional caregivers…
- Trial name
- CORA (NCT04113577)
- Testing
- usability survey
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Patients Hospitalised in Geriatrics
E-vone® Use Detect Falls Among hOspitalized Patients in geRiAtric Medicine
This study evaluates the usability of a new remote warning system for fall in old people. This system is integrated in a shoe. Patients hospitalized in a geriatric ward but also their informal and professional caregivers will…
- Trial name
- EDORA (NCT04067193)
- Testing
- usability survey
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Old Age; Debility, Satisfaction
TIKeasy TAblet satisfaCtion (TikTac)
In the last ten years, gerontechnology is becoming an increasing topic in geriatric medicine. Nevertheless, there are still few studies assessing the usability of technologies in old patients, especially when they are…
- Trial name
- TikTac (NCT04091152)
- Testing
- usability assessment
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Presbycusis, Age Related Hearing Loss
Mitochondrial Genetics of Presbycusis
The main goal of this study is to identify mitochondrial mutations associated with presbycusis. Patients affected by severe presbycusis and normal hearing controls (according to ISO7029 norm) will be enrolled if satisfying…
- Trial name
- MITOPRES (NCT03720964)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Acute Respiratory Distress Syndrome, Acute Lung Injury
Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome
The aim of this multicenter randomized controlled trial is to compare the impact on mortality of patients mechanically ventilated for acute lung injury or acute respiratory distress syndrome of two strategies for setting…
- Trial name
- ExPress (NCT00188058)
- Testing
- Setting of positive end-expiratory pressure
- Where
- 46 sites in France
- Volunteers
- 768 people
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
BIOlogical Response to Exercise : A Metabolomic Study in Peripheral Artery Disease (BIOR)
The measurement of the transcutaneous oxygen pressure during walking allows to estimate the importance of ischemia, bilaterally and segment of limb by segment of limb.
- Trial name
- BIOR (NCT03305198)
- Testing
- Capillary blood sampling from the earlobe
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Angers
Acute Respiratory Distress Syndrome
Comparison of Positive End Expiratory Pressure Titration Methods in ARDS Patients
This study aims at assessing the short-term physiological effects of 2 positive end expiratory pressure titration strategies in patients with ARDS.
- Trial name
- ELSE (NCT03281473)
- Testing
- Strategy 1, Strategy 2
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
COPD Exacerbation
High Flow Oxygen Therapy in Patients Suffering From Chronic Obstructive Pulmonary Disease Exacerbation: Effects and Mechanisms of Action
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is associated with poor outcome, especially when intubation is required, thus underlining the importance of optimizing non-invasive ventilatory support to avoid…
- Trial name
- Oh BPCO (NCT02371564)
- Testing
- High flow humidified oxygen, Standard flow humidified oxygen
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
Shock, Intensive Care
CHangeovers of Norepinephrine in Intensive Care
CHIC study's purpose is to compare the efficiency, in terms of blood pressure stability, of three changeovers of norepinephrine used routinely in ICU. The three techniques are: Quick change Double pumping Smart infusion pumps
- Trial name
- CHIC (NCT02304939)
- Testing
- changeover, use of automatic infusion pump, datas collection
- Where
- France
- Volunteers
- 285 people
- Sponsor
- University Hospital, Angers