Clinical trials: sponsored by University Hospital, Angers
Socialised Disturbance of Conduct
Identification and Research of Impacts of Social Categorization Process in Nurse Triage (SOCIAL SORTING)
Social Sorting is a: non interventional, observational, qualitative and multicenter research. It investigates three French emergency units in three French centers (UH of Angers, H of Le Mans, H of Laval).
- Trial name
- SOCIALSORTING (NCT03379961)
- Where
- 3 sites in France
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Primary Brain Tumor, Neurocognition
Executive and Socio-cognitive Functions in Survivors of Primary Brain Tumor: Impact on Patients' Quality of Life
Significant advances in primary malignant brain tumors (PBT) treatment have led to dramatically improved survival, both in children and adults.
- Conditions
- Primary Brain Tumor, Neurocognition, Quality of Life
- Trial name
- NEUROCOG-QOL (NCT02693405)
- Testing
- Executive functions, social cognition, quality of life
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Septic Shock
Observational Study on Intubation in Septic Shock
Septic shock is common in intensive care and its mortality remains high. While new treatments have not improved survival, optimization of known and widely used techniques has allowed reduction in mortality.
- Trial name
- INTUBATIC (NCT02780466)
- Volunteers
- 859 people
- Sponsor
- University Hospital, Angers
Quality of Health Care
Prevention of Venous Thromboembolism Disease in Emergency Departments
The appropriate use of thromboprophylaxis in medical patients admitted to hospital can substantially reduce the overall burden of disease due to venous thromboembolism.
- Trial name
- PREVENU (NCT01212393)
- Testing
- reminders
- Where
- 23 sites in France
- Volunteers
- 20,000 people
- Sponsor
- University Hospital, Angers
Chest Pain
Interest of CARE Rule to Exclude the Hypothesis of an Acute Coronary Syndrome Without Bioassay - ICARE
Acute coronary syndrome (ACS) is a major health problem and its diagnosis remains a challenge for the emergency physician. The management of a suspected ACS is well codified, based on troponin assays, renewed if necessary.
- Trial name
- ICARE (NCT02813499)
- Testing
- CARE Rule
- Where
- 6 sites in Belgium, France
- Volunteers
- 1,453 people
- Sponsor
- University Hospital, Angers
Fall Patients
Older falleRs : From Emergency to Geriatric Network
The fall is a complex process associated with high morbidity and mortality, with an institutionalization rate of up to 40% and a major socio-economic impact. The prevalence of falls increases with age.
- Trial name
- OREGoN (NCT03488615)
- Where
- France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Angers
Intensive Care, Ventilator Lung
Respiratory Mechanics in Intensive Care Patients
This study aims at assessing the respiratory mechanics of intubated patients in intensive care unit.
- Trial name
- PREMIER (NCT03420417)
- Testing
- Esophageal pressure measurement
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Opioid Substitution Treatment
Content and Expectations of Consultations of Patients With Opioid Substitution Treatment Considered as Stabilized: Cross-Testimonials Doctors - Patients (MSOSuiStab)
Consultations in general medical practice concerning the follow-up of the patients receiving opiate substitution treatments are not exceptional.
- Trial name
- MSOSuiStab (NCT03390829)
- Testing
- semi-directed interviews
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Pseudoxanthoma Elasticum
Biological Collection of Kidney Cells
Our objective is to obtain human induced pluripotent stem cells from urine samples of PXE patients for further proteomic and metabolomic studies and treatment screening.
- Trial name
- CRHiPS (NCT03364504)
- Testing
- urine collection
- Volunteers
- 10 people
- Sponsor
- University Hospital, Angers
Maternal Obesity
Effect of the Maternal Obesity and/or the By-pass on the Growth and the Nutritional Balance of the Child
This study evaluates effect of the Maternal Obesity and/or the By-pass on the Growth and the Nutritional Balance of the Child.The data stemming from mothers presenting obesity or an overweight during their pregnancy and the data…
- Trial name
- SMOOTHIE (NCT03084120)
- Testing
- Collection of bloods samples for the mother, Retrieval of umbilical cord blood., Retrieval of placenta.
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Angers
Postoperative Ileus
Tibial Nerve Stimulation and Postoperative Ileus
Postoperative ileus (POI) causes patient's discomfort and leads to an increase of cost of management after colorectal surgery because of an increase of the morbidity rate or of the rate of early rehospitalization after discharge.
- Trial name
- pre-TAPIOCA (NCT02815956)
- Testing
- percutaneous tibial nerve stimulation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Healthy Volunteers
Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin.
- Trial name
- NCT00152724
- Testing
- pressure strain system, iontophoresis, scopolamin, emla
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Type 2 Diabetes
Hope Theory as Ability Determinant to Permanently Change the Adapted Physical Activity (APA) in Type 2 Diabetic Patients
The control of diabetes is related both to food, treatment but also to physical activity. Despite these recommendations and these positive findings, patients are always sedentary because of brakes in the practice of a regular…
- Trial name
- APADIAB-ESPOIR (NCT02733302)
- Testing
- Hope theory
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Angers
Huntington Disease
Metabolomic Study in Huntington's Disease (METABO-HD)
The purpose of this project is to study Huntington's disease by metabolomic approach.
- Trial name
- NCT03296176
- Testing
- blood sample
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Microcirculation
Use of Laser Speckle to Study Cutaneous Blood Flow at Exercise in Healthy Subjects
We aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow during exercise.
- Trial name
- Speckle-move (NCT01152008)
- Testing
- tourniquet ischemia
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alcoholic Cirrhosis
Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients
The aim of this study was assesment of splanchnic and systemic hemodynamic effects of chronic administration (2 month) of spironolactone or propranolol, alone or in association in alcoholic cirrhotic patients.
- Trial name
- NCT00188045
- Testing
- Propranolol - Spironolactone
- Volunteers
- 54 people
- Sponsor
- University Hospital, Angers
Sleep Apnea
Obstructive Sleep Apnoea in Patients With Intermittent Claudication
The main aim of this study is to determine how common undiagnosed obstructive sleep apnoea is in individuals with intermittent claudication.
- Trial name
- WITH-SAS (NCT01801592)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Genetic Syndrome
Genetic of SportS Induced Endofibrotic Remodeling
search for a genetic cause of vascular endofibrose
- Trial name
- GOSSER (NCT02704260)
- Testing
- GENETIC ANALYSIS
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Lower Limb Amputation at Ankle (Injury)
Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees
Evaluate a new porosthetic device in lower limb amputees.
- Trial name
- PROPRIO-FOOT (NCT02501408)
- Testing
- propriofoot prosthesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Pain, Postoperative
Evaluation of Efficacy of Lumbar Plexus Bloc After Hip Surgery
Compare lumbar plexus block with ropivacaine 0.475%, 0.4 ml/kg to saline. Each group randomized, includes 30 patients. block performed preoperatively Surgery under general anesthesia.
- Trial name
- NCT00150865
- Testing
- ropivacaine
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers