Clinical trials: sponsored by University Hospital, Angers
Chronic Hepatitis C
Use or Non-use of Epoetin Beta in Patients Infected by Chronic Hepatitis C
The purpose is to demonstrate a correction of anemia in hepatitis C virus treatment with peginterferon plus ribavirin.
- Trial name
- NCT00262379
- Testing
- epoetin beta (NeoRecormon®)
- Where
- 37 sites in France
- Volunteers
- 229 people
- Sponsor
- University Hospital, Angers
Liver Fibrosis
Screening of Fibrosing and/or Viral Chronic Hepatopathies in Jail
The prevalence of chronic hepatopathies is high in jail. However, the medical care of these hepatopathies is few developed. This study is an observational, an epidemiologic (screening and prevalence of fibrosing hepatopathies)…
- Trial name
- SNIFF11 (NCT00453869)
- Testing
- liver fibrosis evaluation
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Angers
Neuroregulation of Breathing
Effects of Abnormal Respiratory Mechanics and Assisted Mechanical Ventilation on Neuro-regulation of Respiration
Due to recent technological improvements, it is now possible to record the electrical activity of the diaphragm (Eadi), a direct expression of the central nervous system respiratory center activity.
- Trial name
- RegAIN (NCT01818219)
- Testing
- Records of EADI derived parameters
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Septic Shock, Adult Respiratory Distress Syndrome
Hyperoxia and Hypertonic Saline in Septic Shock
Assessment of the effect of hyperoxia and hypertonic saline on survival in patients with septic shock Hyperoxia and hypertonic saline may have beneficial effects on organ perfusion and oxygenation and may reduce the organ failure…
- Trial name
- Hyper2S (NCT01722422)
- Testing
- oxygen and saline
- Where
- France
- Volunteers
- 441 people
- Sponsor
- University Hospital, Angers
Oxygen Inhalation Therapy
Trial Aiming at Assessing the Effect of Humidification on the Comfort of the Patient Receiving an Oxygen Therapy
In France, the most used humidifying system during oxygen therapy is a non heated device with weak efficiency and non-proven clinical benefits.
- Trial name
- OXYREA (NCT01300845)
- Testing
- Humidification, No Humidification
- Where
- France
- Volunteers
- 356 people
- Sponsor
- University Hospital, Angers
Safe Volunteers, Kidney Transplant Recipients
Study of the Renal Perfusion in Healthy Volunteers and Renal Transplant Recipients During an Orthostatic Stress
Autonomic nervous system contributes to the regulation of renal blood flow, affected by upright posture. Kidney transplantation implies sympathetic denervation.
- Trial name
- ortho_rein (NCT02179411)
- Testing
- tilt test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Leber Hereditary Optic Neuropathy
Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy
The Leber Hereditary Optic Neuropathy is a genetic disorder caused by maternal transmission of mitochondrial DesoxiroboNucleid Acid mutations.
- Trial name
- CICLO-NOHL (NCT02176733)
- Testing
- cyclosporine
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Angers
to Elaborate a New Simple Clinical Tool for the Risk of Falls Among Older Inpatients.
Prediction of Falls in Older Inpatients Hospitalized at Angers University Hospital
The primary objective of this study is to elaborate a new simple clinical tool for the risk of falls among older inpatients.
- Trial name
- EPRIC (NCT02120209)
- Where
- France
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Angers
Acute Myelogenous Leukemia
Study to Assess Dasatinib in Patients With Core Binding Factors Acute Myelogenous Leukemia
In patients with Core Binding Factors Acute Myelogenous Leukemia, the level of Minimal Residual Disease after chemotherapy is predictive of relapse.
- Trial name
- DasaCBF (NCT02113319)
- Testing
- dasatinib
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Angers
Huntington's Disease
Multicentric Trial of the Treatment of Huntington's Disease by Cysteamine (RP103)
The purpose of this study is to evaluate the effect of cysteamine in patients with symptomatic Huntington's disease by comparing two groups of patients (cysteamine vs placebo) on the results of the Unified Huntington's Disease…
- Trial name
- NCT02101957
- Testing
- RP103
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Angers
Non-small Cell Lung Cancer
Identification by Microarrays of the Risks of Metastatic Relapse, Toxicity and Resistance to Adjuvant Chemotherapy in Completely Resected Non-small Cell Lung Cancer
Description of new transcriptional profiles associated with risk of relapse and identification of specific sites of relapse in non-small cell lung cancer, toxicity and resistance to adjuvant chemotherapy in completely resected…
- Trial name
- SITRR (NCT02075957)
- Where
- France
- Volunteers
- 192 people
- Sponsor
- University Hospital, Angers
Non-small Cell Lung Cancer Metastatic or Non-small Cell Lung Cancer Recurrent, No EGFR Activating Mutation
Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patient
In France, lung cancer is the leading cause of death induced by cancer. Therapeutic advances have been made in therapy of unresectable non-small cell lung cancer (NSCLC) with tyrosine kinase receptor inhibitors blocking the…
- Trial name
- FLT-THERA (NCT02069418)
- Testing
- 18F-FLT-TEP, 18F-FDG-TEP
- Where
- 8 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Angers
Chronic Low Back Pain
Effect of Three Therapeutics Strategies on Patients With a Chronic Back Pain (PLURICLEF).
Effect of three therapeutics strategies on the restriction of the participation of patients with a chronic back pain : multidisciplinary is it the key component ?
- Trial name
- PLURICLEF (NCT02030171)
- Testing
- functionnal reeducation
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Angers
Obstructive Sleep Apnea
Impact of Polyphenols on Endothelial Function in Obstructive Sleep Apnea
Severe obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity and mortality. Endothelial dysfunction, an early marker of vascular disease has been demonstrated in OSA.
- Trial name
- PolySAS (NCT01977924)
- Testing
- one month polyphenols supplementation (600mg)
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Obliterating Arteriopathy of the Lower Limbs
Protection of Arteritic Patients by Remote Preconditioning
Prospective, monocentric, randomised, double-blind study with 20 patients enrolled to be explored twice through a Cross-over strategy to determine whether remote preconditioning improves arteritic patients' ability to walk.
- Trial name
- PARADIS (NCT01971879)
- Testing
- Remote ischemic preconditioning, Control
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Myocardial Infarction
Remote Ischemic Preconditioning Combined to Local Ischemic Postconditioning in Acute Myocardial Infarction
RIRE-1 is a randomized, open-label with blinded end-point study that will test the hypothesis that remote ischemic preconditioning initiated at the time of the admission in the cathlab reduces infarct size in ST-segment elevation…
- Trial name
- RIRE-1 (NCT01390142)
- Testing
- Control, RIPer, RIPer + IPost
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Anxiety
Reassessment of Premedication in Surgery
The purpose of this study is to test the level of anxiety in patients, the day before surgery (late afternoon) and immediately prior to surgery in 3 parallel groups of patients.
- Trial name
- PREMED (NCT01549691)
- Testing
- Zopiclone, Alprazolam
- Where
- 8 sites in France
- Volunteers
- 455 people
- Sponsor
- University Hospital, Angers
Claudication
Intra-arterial Measurement of pO2 in Walking Induced Transient Hack Profiles
Confirm with invasive measurement the presence of a Walking-Induced Transient Hack (WITH) profile
- Trial name
- Initial-VHS (NCT01022606)
- Testing
- Arterial sampling
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
Feasibility of Home-based Measurement of Walking Capacity Using Global Positioning System in Peripheral Artery Disease
The purpose of this study is to assess the feasibility of home-based measurement of walking capacity in peripheral arterial disease (PAD) patients, uing the Global Positioning System (GPS).
- Trial name
- POST-GPS (NCT01141361)
- Testing
- GPS recording(s) of walking capacity in PAD patients
- Where
- France
- Volunteers
- 251 people
- Sponsor
- University Hospital, Angers
Peripheral Artery Disease
Arterial Inflow and Muscle Ischemia During Calf Stimulation With the Veinoplus Device
Stimulation of arterial inflow to the lower limb is important to obtain functional improvement in peripheral artery diseased (PAD) patients with claudication.
- Trial name
- NCT01592812
- Testing
- electrical muscle stimulation
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers